PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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6RH4	Human Carbonic Anhydrase II in complex with 4-Nitrobenzenesulfonamide. 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-nitrobenzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-04-18 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.948 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
8OE6	Structure of hyperstable haloalkane dehalogenase variant DhaA231 分子名称: CHLORIDE ION, MAGNESIUM ION, Structure of hyperstable haloalkane dehalogenase variant DhaA231 著者 Marek, M. 登録日 2023-03-10 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning. Acs Catalysis, 13, 2023
1R9D	Glycerol bound form of the B12-independent glycerol dehydratase from Clostridium butyricum 分子名称: GLYCEROL, glycerol dehydratase 著者 Lanzilotta, W.N, O'Brien, J.R, Raynaud, C, Soucaille, P. 登録日 2003-10-28 公開日 2004-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization. Biochemistry, 43, 2004
8OE2	Structure of hyperstable haloalkane dehalogenase variant DhaA223 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... 著者 Marek, M. 登録日 2023-03-10 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning. Acs Catalysis, 13, 2023
1R8W	Native structure of the B12-independent glycerol dehydratase from clostridium butyricum 分子名称: glycerol dehydratase 著者 Lanzilotta, W.N, Soucaille, P, O'Brien, J.R, Raynaud, C. 登録日 2003-10-28 公開日 2004-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization. Biochemistry, 43, 2004
8K5T	The structure of EntE with2-methyl-3-chloro-benzoic acid sulfamoyl adenosine 分子名称: Enterobactin synthase component E, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-(3-chloranyl-2-methyl-phenyl)carbonylsulfamate 著者 Miyanaga, A, Ishikawa, F. 登録日 2023-07-24 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Reprogrammed aryl acid adenylation domain with an enlarged substrate binding pocket To be published
8K5S	The structure of EntE with 3-(prop-2-yn-1-yloxy)benzoic acid sulfamoyl adenosine 分子名称: Enterobactin synthase component E, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-(3-prop-2-ynoxyphenyl)carbonylsulfamate 著者 Miyanaga, A, Ishikawa, F. 登録日 2023-07-24 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Reprogrammed aryl acid adenylation domain with an enlarged substrate binding pocket To be published
1P18	Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, K68R mutant, ternary substrates complex 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, MAGNESIUM ION, ... 著者 Canyuk, B, Eakin, A.E, Craig III, S.P. 登録日 2003-04-11 公開日 2004-05-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase J.Mol.Biol., 335, 2004
5I4Q	Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) 分子名称: CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... 著者 Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) 登録日 2016-02-12 公開日 2017-06-28 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
1RF8	Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ... 著者 Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G. 登録日 2003-11-07 公開日 2003-12-23 最終更新日 2024-03-06 実験手法 SOLUTION NMR 主引用文献 Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell(Cambridge,Mass.), 115, 2003
3RSZ	Maltodextran bound basal state conformation of yeast glycogen synthase isoform 2 分子名称: Glycogen [starch] synthase isoform 2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Baskaran, S, Hurley, T.D. 登録日 2011-05-02 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.009 Å) 主引用文献 Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen. J.Biol.Chem., 286, 2011
4GS7	Structure of the Interleukin-15 quaternary complex 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ring, A.M, Ozkan, E, Feng, D, Garcia, K.C. 登録日 2012-08-27 公開日 2012-11-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15. Nat.Immunol., 13, 2012
6MB5	AAC-IIIb binary with NEOMYCIN 分子名称: Aac(3)-IIIb protein, NEOMYCIN 著者 Cuneo, M.J, Kumar, P. 登録日 2018-08-29 公開日 2018-11-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase. J. Med. Chem., 61, 2018
1MXH	Crystal Structure of Substrate Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi 分子名称: DIHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 著者 Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. 登録日 2002-10-02 公開日 2003-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
1FJ0	STRUCTURE DETERMINATION OF THE FERRICYTOCHROME C2 FROM RHODOPSEUDOMONAS PALUSTRIS 分子名称: CYTOCHROME C2, GLYCEROL, HEME C, ... 著者 Geremia, S. 登録日 2000-08-07 公開日 2002-01-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cleavage of the iron-methionine bond in c-type cytochromes: Crystal structure of oxidized and reduced cytochrome c(2) from Rhodopseudomonas palustris and its ammonia complex. Protein Sci., 11, 2002
6SD7	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide and its dimer 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 2,3,4,5,6-pentafluoro-N-(2,3,5,6-tetrafluoro-4-sulfamoylphenyl)benzenesulfonamide, 2,3,4,5,6-pentafluorobenzenesulfonamide, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-07-26 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
6SCH	NADH-dependent variant of CBADH 分子名称: MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Selles Vidal, L, Murray, J.W, Heap, J.T. 登録日 2019-07-24 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Versatile selective evolutionary pressure using synthetic defect in universal metabolism. Nat Commun, 12, 2021
4E3T	Round 18 Arylesterase Variant of Phosphotriesterase with Bound Transition State Analog 分子名称: Phosphotriesterase, ZINC ION, hexyl(naphthalen-2-yloxy)phosphinic acid 著者 Tokuriki, N, Jackson, C.J, Tawfik, D.S. 登録日 2012-03-10 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3, 2012
6K4K	Crystal structure of SidJ-CaM binary complex at 2.71 A 分子名称: CALCIUM ION, Calmodulin-1, SidJ 著者 Ouyang, S.Y. 登録日 2019-05-24 公開日 2019-07-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.715 Å) 主引用文献 Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase. Nature, 572, 2019
6K4R	Crystal structure of SidJ-CaM-AMP ternary complex at 3.11 A 分子名称: ADENOSINE MONOPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... 著者 Ouyang, S.Y. 登録日 2019-05-26 公開日 2019-07-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.109 Å) 主引用文献 Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase. Nature, 572, 2019
3TEH	Crystal structure of Thermus thermophilus Phenylalanyl-tRNA synthetase complexed with L-dopa 分子名称: 3,4-DIHYDROXYPHENYLALANINE, Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain 著者 Safro, M, Klipcan, L, Moor, N. 登録日 2011-08-14 公開日 2011-11-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8524 Å) 主引用文献 Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNA(Phe) with 3,4-Dihydroxy-L-Phenylalanine. Chem.Biol., 18, 2011
5TOV	Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in binary complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Adenosylhomocysteinase, CHLORIDE ION 著者 Czyrko, J, Brzezinski, K. 登録日 2016-10-19 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies. Int. J. Biol. Macromol., 104, 2017
3GST	STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE 分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION 著者 Ji, X, Ammon, H.L, Armstrong, R.N, Gilliland, G.L. 登録日 1993-06-07 公開日 1993-10-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry, 33, 1994
6M7W	Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins 分子名称: Phosphorelay intermediate protein YPD1 著者 Menon, S.K, Soni, K.S, West, A.H. 登録日 2018-08-21 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins. BMC Biochem., 20, 2019
5G1N	Aspartate transcarbamoylase domain of human CAD bound to PALA 分子名称: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID 著者 Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S. 登録日 2016-03-29 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala. Structure, 24, 2016

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