2ZIL
 
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2ZK9
 | | Crystal Structure of Protein-glutaminase | | 分子名称: | GLYCEROL, Protein-glutaminase, SODIUM ION | | 著者 | Hashizume, R. | | 登録日 | 2008-03-13 | | 公開日 | 2009-03-17 | | 最終更新日 | 2012-08-29 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex
J.Biol.Chem., 286, 2011
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3D1Y
 | | Crystal structure of HIV-1 mutant I54V and inhibitor SAQUINA | | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, HIV-1 Protease, ... | | 著者 | Liu, F, Weber, I.T. | | 登録日 | 2008-05-06 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir.
J.Mol.Biol., 381, 2008
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3CKU
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3AZ6
 | | Crystal structure of Co/T-HEWL | | 分子名称: | CHLORIDE ION, COBALT (II) ION, GLYCEROL, ... | | 著者 | Abe, S, Tsujimoto, M, Yoneda, K, Ohba, M, Hikage, T, Takano, M, Kitagawa, S, Ueno, T. | | 登録日 | 2011-05-20 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Porous protein crystals as reaction vessels for controlling magnetic properties of nanoparticles
Small, 8, 2012
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3B9G
 | | Crystal structure of loop deletion mutant of Trypanosoma vivax nucleoside hydrolase (3GTvNH) in complex with ImmH | | 分子名称: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase, ... | | 著者 | Vandemeulebroucke, A, De Vos, S, Van Holsbeke, E, Steyaert, J, Versees, W. | | 登録日 | 2007-11-05 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Flexible Loop as a Functional Element in the Catalytic Mechanism of Nucleoside Hydrolase from Trypanosoma vivax.
J.Biol.Chem., 283, 2008
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3AZ7
 | | Crystal structure of Pt/T-HEWL | | 分子名称: | Lysozyme C, PLATINUM (II) ION, SODIUM ION | | 著者 | Abe, S, Tsujimoto, M, Yoneda, K, Ohba, M, Hikage, T, Takano, M, Kitagawa, S, Ueno, T. | | 登録日 | 2011-05-20 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Porous protein crystals as reaction vessels for controlling magnetic properties of nanoparticles
Small, 8, 2012
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3CPE
 | | Crystal Structure of T4 gp17 | | 分子名称: | DNA packaging protein Gp17, PHOSPHATE ION, SODIUM ION | | 著者 | Sun, S, Rossmann, M.G. | | 登録日 | 2008-03-31 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structure of the phage T4 DNA packaging motor suggests a mechanism dependent on electrostatic forces
Cell(Cambridge,Mass.), 135, 2008
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3D76
 | | Crystal structure of a pheromone binding protein mutant D35N, from Apis mellifera, soaked at pH 7.0 | | 分子名称: | 1,2-ETHANEDIOL, N-BUTYL-BENZENESULFONAMIDE, Pheromone-binding protein ASP1, ... | | 著者 | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | | 登録日 | 2008-05-20 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release
J.Mol.Biol., 390, 2009
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1EZ1
 | | STRUCTURE OF ESCHERICHIA COLI PURT-ENCODED GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE COMPLEXED WITH MG, AMPPNP, AND GAR | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ACETATE ION, GLYCINAMIDE RIBONUCLEOTIDE, ... | | 著者 | Thoden, J.B, Firestine, S, Nixon, A, Benkovic, S.J, Holden, H.M. | | 登録日 | 2000-05-09 | | 公開日 | 2000-08-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular structure of Escherichia coli PurT-encoded glycinamide ribonucleotide transformylase.
Biochemistry, 39, 2000
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1HZY
 | | HIGH RESOLUTION STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA | | 分子名称: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, FORMIC ACID, ... | | 著者 | Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. | | 登録日 | 2001-01-26 | | 公開日 | 2001-04-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta.
Biochemistry, 40, 2001
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3D32
 | | Complex of GABA(A) receptor-associated protein (GABARAP) with a synthetic peptide | | 分子名称: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, K1 peptide, ... | | 著者 | Weiergraeber, O.H, Stangler, T, Willbold, D. | | 登録日 | 2008-05-09 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Ligand Binding Mode of GABA(A) Receptor-Associated Protein.
J.Mol.Biol., 381, 2008
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1J8G
 | | X-ray Analysis of a RNA Tetraplex r(uggggu)4 at Ultra-High Resolution | | 分子名称: | 5'-R(*UP*GP*GP*GP*GP*U)-3', CALCIUM ION, SODIUM ION, ... | | 著者 | Deng, J, Xiong, Y, Sundaralingam, M. | | 登録日 | 2001-05-21 | | 公開日 | 2001-11-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (0.61 Å) | | 主引用文献 | X-ray analysis of an RNA tetraplex (UGGGGU)(4) with divalent Sr(2+) ions at subatomic resolution (0.61 A).
Proc.Natl.Acad.Sci.USA, 98, 2001
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1IUE
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8P1T
 | | Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor Z237451470 | | 分子名称: | 1,2-ETHANEDIOL, 6-cyclopropyl-~{N}-(1~{H}-indazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxamide, CHLORIDE ION, ... | | 著者 | Thomsen, M, Thieulin-Pardo, G, Neumann, L. | | 登録日 | 2023-05-12 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.442 Å) | | 主引用文献 | Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening.
Bioorg.Med.Chem.Lett., 94, 2023
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8SV0
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5IJQ
 | | Crystal structure of autotaxin (ENPP2) re-refined | | 分子名称: | 7alpha-hydroxycholesterol, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... | | 著者 | Hausmann, J, Joosten, R.P, Perrakis, A. | | 登録日 | 2016-03-02 | | 公開日 | 2016-06-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin.
J.Struct.Biol., 195, 2016
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5ICM
 | | 17beta-hydroxysteroid dehydrogenase type 14 in complex with a non-steroidal inhibitor | | 分子名称: | 17-beta-hydroxysteroid dehydrogenase 14, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | | 著者 | Bertoletti, N, Braun, F, Marchais-Oberwinkler, S, Heine, A, Klebe, G. | | 登録日 | 2016-02-23 | | 公開日 | 2016-07-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.
J.Med.Chem., 59, 2016
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7ZHM
 | | Salmonella enterica Rhs1 C-terminal toxin TreTu complex with TriTu immunity protein | | 分子名称: | Immunity protein TriTu, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Rhs1 protein, ... | | 著者 | Jurenas, D, Rey, M, Chamot-Rooke, J, Terradot, L, Cascales, E. | | 登録日 | 2022-04-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Salmonella antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of EF-Tu P-loop.
Nucleic Acids Res., 50, 2022
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8SLX
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7PG6
 | | Crystal Structure of PI3Kalpha in complex with the inhibitor NVP-BYL719 | | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | | 著者 | Gong, G, Pinotsis, N, Williams, R.L, Vanhaesebroeck, B. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.49943733 Å) | | 主引用文献 | A small-molecule PI3K alpha activator for cardioprotection and neuroregeneration.
Nature, 618, 2023
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8SLY
 | | Rat TRPV2 bound with 2 CBD ligands in nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... | | 著者 | Tan, X, Swartz, K.J. | | 登録日 | 2023-04-24 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
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7PFL
 | | The SARS-CoV2 major protease (Mpro) apo structure to 1.8 A resolution | | 分子名称: | Replicase polyprotein 1ab, SODIUM ION | | 著者 | Moche, M, Moodie, L, Strandback, E, Nyman, T, Akaberi, D, Lennerstrand, J. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The SARS-CoV2 major protease (Mpro) in complex with a non-covalent inhibitory ligand at 2 A resolution
To Be Published
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5II0
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7ZKO
 | | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form delta | | 分子名称: | 3-[13-methyl-5,7,12,14-tetrakis(oxidanylidene)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]propyl 3-[5,7,12,14-tetrakis(oxidanylidene)-13-(3-oxidanylpropyl)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1,3,8(16),9,11(15)-pentaen-6-yl]propyl hydrogen phosphate, 3-[5-[3-bis(oxidanyl)phosphanyloxypropoxy]naphthalen-1-yl]oxypropyl 3-(5-oxidanylnaphthalen-1-yl)oxypropyl hydrogen phosphate, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | 著者 | Troisi, R, Sica, F. | | 登録日 | 2022-04-13 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers.
Mol Ther Nucleic Acids, 30, 2022
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