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8PQX
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p97 (VCP) mutant - F539A state III
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
登録日2023-07-12
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献p97 (VCP) mutant - F539A state III
To Be Published
4KO8
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BU of 4ko8 by Molmil
Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
7VCU
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BU of 7vcu by Molmil
Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCT
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Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCX
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Human p97 single hexamer conformer II with ATPgammaS bound
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCS
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BU of 7vcs by Molmil
Human p97 double hexamer conformer II with ATPgammaS bound
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-03
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
7VCV
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BU of 7vcv by Molmil
Human p97 single hexamer conformer I with ATPgammaS bound
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Gao, H, Li, F, Shi, Z, Li, Y, Yu, H.
登録日2021-09-04
公開日2022-03-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
4KOD
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BU of 4kod by Molmil
Structure of p97 N-D1 R155H mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
4KDI
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BU of 4kdi by Molmil
Crystal structure of p97/VCP N in complex with OTU1 UBXL
分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1
著者Kim, S.J, Kim, E.E.
登録日2013-04-25
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
5C19
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BU of 5c19 by Molmil
p97 variant 2 in the apo state
分子名称: SULFATE ION, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C1B
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BU of 5c1b by Molmil
p97-delta709-728 in complex with a UFD1-SHP peptide
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions.
Structure, 24, 2016
5C1A
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BU of 5c1a by Molmil
p97-N750D/R753D/M757D/Q760D in complex with ATP-gamma-S
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
8DAW
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BU of 8daw by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uD)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAU
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BU of 8dau by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAR
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BU of 8dar by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAT
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BU of 8dat by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intB)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAS
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BU of 8das by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAV
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BU of 8dav by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uC)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Lee, H.G, Lima, C.D.
登録日2022-06-14
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
5DYI
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BU of 5dyi by Molmil
Structure of p97 N-D1 wild-type in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Tang, W.K, Xia, D.
登録日2015-09-24
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain.
Sci Rep, 6, 2016
5DYG
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BU of 5dyg by Molmil
Structure of p97 N-D1 L198W mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Tang, W.K, Xia, D.
登録日2015-09-24
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain.
Sci Rep, 6, 2016
5EPP
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BU of 5epp by Molmil
Structural Insights into the Interaction of p97 N-terminus Domain and VBM Motif in Rhomboid Protease, RHBDL4
分子名称: Rhomboid-related protein 4, Transitional endoplasmic reticulum ATPase
著者Lim, J.J, Lee, Y, Ly, T.T, Kang, J.Y, Lee, J.-G, An, J.Y, Youn, H.-S, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H.
登録日2015-11-12
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4.
Biochem.J., 473, 2016
8FCR
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BU of 8fcr by Molmil
Cryo-EM structure of p97:UBXD1 H4-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6
著者Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R.
登録日2022-12-01
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.
Nat.Struct.Mol.Biol., 30, 2023
8FCT
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Cryo-EM structure of p97:UBXD1 lariat mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6
著者Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R.
登録日2022-12-01
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.
Nat.Struct.Mol.Biol., 30, 2023
8FCQ
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BU of 8fcq by Molmil
Cryo-EM structure of p97:UBXD1 PUB-in state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6
著者Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R.
登録日2022-12-01
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.
Nat.Struct.Mol.Biol., 30, 2023
8FCM
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BU of 8fcm by Molmil
Cryo-EM structure of p97:UBXD1 open state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6
著者Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R.
登録日2022-12-01
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-08-07に公開中

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