5AX3
 
 | | Crystal structure of ERK2 complexed with allosteric and ATP-competitive inhibitors. | | 分子名称: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Mitogen-activated protein kinase 1, allosteric and ATP-competitive inhibitor | | 著者 | Kinoshita, T, Sugiyama, H, Mori, Y, Takahashi, N, Tomonaga, A. | | 登録日 | 2015-07-14 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.984 Å) | | 主引用文献 | Identification of allosteric ERK2 inhibitors through in silico biased screening and competitive binding assay
Bioorg.Med.Chem.Lett., 26, 2016
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1X0F
 | | Complex structure of the C-terminal RNA-binding domain of hnRNP D(AUF1) with telomeric DNA | | 分子名称: | 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0 | | 著者 | Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M. | | 登録日 | 2005-03-22 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.
J.Biol.Chem., 280, 2005
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5AUZ
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1X2Q
 | | Solution structure of the SH3 domain of the Signal transducing adaptor molecule 2 | | 分子名称: | Signal transducing adapter molecule 2 | | 著者 | Chikayama, E, Kigawa, T, Sato, M, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-26 | | 公開日 | 2005-10-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH3 domain of the Signal transducing adaptor molecule 2
To be Published
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1X4A
 | | Solution structure of RRM domain in splicing factor SF2 | | 分子名称: | splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) variant | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-14 | | 公開日 | 2005-11-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RRM domain in splicing factor SF2
To be Published
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1X2K
 | | Solution Structure of the SH3 Domain of Human osteoclast stimulating factor 1 (OSTF1) | | 分子名称: | Osteoclast stimulating factor 1 | | 著者 | Kamatari, Y.O, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-25 | | 公開日 | 2005-10-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the SH3 Domain of Human osteoclast stimulating factor 1 (OSTF1)
To be Published
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1X5J
 | | The solution structure of the fifth fibronectin type III domain of human Neogenin | | 分子名称: | Neogenin | | 著者 | Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-15 | | 公開日 | 2005-11-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the fifth fibronectin type III domain of human Neogenin
To be Published
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1X5W
 | | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2 | | 分子名称: | ZINC ION, Zinc finger protein 64, isoforms 1 | | 著者 | Yoneyama, M, Koshiba, S, Tochio, N, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2
To be Published
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1X47
 | | Solution structure of DSRM domain in DGCR8 protein | | 分子名称: | DGCR8 protein | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-14 | | 公開日 | 2005-11-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of DSRM domain in DGCR8 protein
To be Published
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1WHY
 | | Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180 | | 分子名称: | hypothetical protein RIKEN cDNA 1810017N16 | | 著者 | Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-28 | | 公開日 | 2004-11-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180
To be Published
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1X5Z
 | | Solution structure of the fibronectin type-III domain of human protein tyrosine phosphatase, receptor type, D isoform 4 variant | | 分子名称: | Receptor-type tyrosine-protein phosphatase delta | | 著者 | Yoneyama, M, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-17 | | 公開日 | 2005-11-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the fibronectin type-III domain of human protein tyrosine phosphatase, receptor type, D isoform 4 variant
To be Published
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1X1R
 | | Crystal structure of M-Ras in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras | | 著者 | Ye, M, Shima, F, Muraoka, S, Liao, J, Okamoto, H, Yamamoto, M, Tamura, A, Yagi, N, Ueki, T, Kataoka, T. | | 登録日 | 2005-04-12 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
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1X2T
 | | Crystal Structure of Habu IX-bp at pH 6.5 | | 分子名称: | CALCIUM ION, Coagulation factor IX/X-binding protein A chain, Coagulation factor IX/factor X-binding protein B chain, ... | | 著者 | Suzuki, N, Fujimoto, Z, Morita, T, Fukamizu, A, Mizuno, H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-10-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | pH-Dependent Structural Changes at Ca(2+)-binding sites of Coagulation Factor IX-binding Protein
J.Mol.Biol., 353, 2005
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3UNK
 | | CDK2 in complex with inhibitor YL5-083 | | 分子名称: | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Cyclin-dependent kinase 2, PHOSPHATE ION | | 著者 | Zhu, J.-Y, Martin, M.P, Alam, R, Schonbrunn, E. | | 登録日 | 2011-11-15 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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1X5S
 | | Solution structure of RRM domain in A18 hnRNP | | 分子名称: | Cold-inducible RNA-binding protein | | 著者 | Sato, A, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-16 | | 公開日 | 2005-11-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RRM domain in A18 hnRNP
To be Published
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1WQO
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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3UNZ
 | | Aurora A in Complex with RPM1679 | | 分子名称: | 1,2-ETHANEDIOL, 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2011-11-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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1WQP
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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1WQM
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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1WQN
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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1WQQ
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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1WQR
 | | CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | | 登録日 | 1998-02-09 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry, 37, 1998
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3UOH
 | | Aurora A in complex with RPM1722 | | 分子名称: | 1,2-ETHANEDIOL, 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2011-11-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8002 Å) | | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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3UOK
 | | Aurora A in complex with YL5-81-1 | | 分子名称: | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid, Aurora kinase A | | 著者 | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | | 登録日 | 2011-11-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9506 Å) | | 主引用文献 | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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1WFC
 | | STRUCTURE OF APO, UNPHOSPHORYLATED, P38 MITOGEN ACTIVATED PROTEIN KINASE P38 (P38 MAP KINASE) THE MAMMALIAN HOMOLOGUE OF THE YEAST HOG1 PROTEIN | | 分子名称: | MITOGEN-ACTIVATED PROTEIN KINASE P38 | | 著者 | Wilson, K.P, Fitzgibbon, M.J, Caron, P.R, Griffith, J.P, Chen, W, Mccaffrey, P.G, Chambers, S.P, Su, M.S.-S. | | 登録日 | 1996-09-13 | | 公開日 | 1997-09-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of p38 mitogen-activated protein kinase.
J.Biol.Chem., 271, 1996
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