5ZM4
 
 | | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AndA with preandiloid C | | 分子名称: | (6aS,8aR,12aS,12bR,13aR)-5,6a,9,9,12a,13a-hexamethyl-7,8,8a,9,12a,12b,13,13a-octahydro-3H-benzo[a]furo[3,4-j]xanthene-3,4,10(1H,6aH)-trione, 2-OXOGLUTARIC ACID, Dioxygenase andA, ... | | 著者 | Nakashima, Y, Senda, T. | | 登録日 | 2018-04-01 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and Computational Bases for Dramatic Skeletal Rearrangement in Anditomin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
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4WX1
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4YBM
 | | Crystal structure of TRIM24 PHD-bromodomain complexed with N-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide (7b) | | 分子名称: | GLYCEROL, N-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-3,4-dimethoxybenzenesulfonamide, SULFATE ION, ... | | 著者 | Poncet-Montange, G, Palmer, W, Jones, P. | | 登録日 | 2015-02-18 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
J.Med.Chem., 59, 2016
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4YB7
 | | Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni in complex with ATP | | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ATP phosphoribosyltransferase, ... | | 著者 | Mittelstaedt, G, Moggre, G.-J, Parker, E.J. | | 登録日 | 2015-02-18 | | 公開日 | 2016-03-09 | | 最終更新日 | 2018-09-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
Protein Sci., 25, 2016
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5YYB
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5Z01
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5YZO
 | | Crystal structure of S9 peptidase mutant (S514A) from Deinococcus radiodurans R1 | | 分子名称: | Acyl-peptide hydrolase, putative, DIMETHYL SULFOXIDE, ... | | 著者 | Yadav, P, Jamdar, S.N, Kumar, A, Ghosh, B, Makde, R.D. | | 登録日 | 2017-12-15 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms.
J.Biol.Chem., 294, 2019
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4YF0
 | | HU38-19bp | | 分子名称: | DNA-binding protein HU-alpha, synthetic DNA strand | | 著者 | Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D. | | 登録日 | 2015-02-24 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
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4YEL
 | | Tailspike protein double mutant D339A/E372A of E. coli bacteriophage HK620 in complex with hexasaccharide | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... | | 著者 | Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. | | 登録日 | 2015-02-24 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
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4YHE
 | | NATIVE BACTEROIDETES-AFFILIATED GH5 CELLULASE LINKED WITH A POLYSACCHARIDE UTILIZATION LOCUS | | 分子名称: | GH5 | | 著者 | Naas, A.E, MacKenzie, A.K, Dalhus, B, Eijsink, V.G.H, Pope, P.B. | | 登録日 | 2015-02-27 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Features of a Bacteroidetes-Affiliated Cellulase Linked with a Polysaccharide Utilization Locus.
Sci Rep, 5, 2015
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4YLE
 | | Crystal structure of an ABC transpoter solute binding protein (IPR025997) from Burkholderia multivorans (Bmul_1631, Target EFI-511115) with an unknown ligand modelled as alpha-D-erythrofuranose | | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, UNKNOWN LIGAND | | 著者 | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2015-03-05 | | 公開日 | 2015-04-15 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of an ABC transporter solute binding protein (IPR025997) from Burkholderia multivorans (Bmul_1631, Target EFI-511115) with an unknown ligand modelled as alpha-D-erythrofuranose
To be published
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4YMG
 | | Crystal structure of SAM-bound Podospora anserina methyltransferase PaMTH1 | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Putative SAM-dependent O-methyltranferase, ... | | 著者 | Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H. | | 登録日 | 2015-03-06 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
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4YIQ
 | | Structure of the CEACAM6-CEACAM8 heterodimer | | 分子名称: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, ... | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2015-03-02 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5ZB8
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5Z5U
 | | The first bromodomain of BRD4 with compound BDF-2254 | | 分子名称: | 2-amino-4-(1H-imidazol-1-yl)quinoline-6,8-diol, Bromodomain-containing protein 4 | | 著者 | Zhang, H, Luo, C. | | 登録日 | 2018-01-20 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | | 主引用文献 | Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.
Oncogenesis, 7, 2018
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5Z6O
 | | Crystal structure of Penicillium cyclopium protease | | 分子名称: | CALCIUM ION, phenylmethanesulfonic acid, protease | | 著者 | Ko, T.-P, Koszelak, S, Ng, J, Day, J, Greenwood, A, McPherson, A. | | 登録日 | 2018-01-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The crystallographic structure of the subtilisin protease from Penicillium cyclopium.
Biochemistry, 36, 1997
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5ZEF
 | | Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A | | 分子名称: | 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... | | 著者 | Malik, A, Dalal, V, Ankri, S, Tomar, S. | | 登録日 | 2018-02-27 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
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5Z98
 | | Crystal Structure of the Primate APOBEC3H Dimer mediated by RNA Duplex | | 分子名称: | Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like protein 3H, RNA (5'-R(*AP*UP*AP*CP*CP*CP*GP*GP*CP*A)-3'), RNA (5'-R(P*CP*UP*GP*CP*CP*GP*GP*GP*UP*A)-3'), ... | | 著者 | Matsuoka, T, Nagae, T, Ode, H, Watanabe, N, Iwatani, Y. | | 登録日 | 2018-02-02 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA.
Nucleic Acids Res., 46, 2018
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5ZA0
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4YSF
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4YNI
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4YON
 | | P-Rex1:Rac1 complex | | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Lucato, C.M, Whisstock, J.C, Ellisdon, A.M. | | 登録日 | 2015-03-11 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
J.Biol.Chem., 290, 2015
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4YX5
 | | SpaO(SPOA1,2) | | 分子名称: | CHLORIDE ION, Surface presentation of antigens protein SpaO | | 著者 | Notti, R.Q, Stebbins, C.E. | | 登録日 | 2015-03-22 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9001 Å) | | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
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5ZOJ
 | | Crystal structure of human SMAD2-MAN1 complex | | 分子名称: | Inner nuclear membrane protein Man1, Mothers against decapentaplegic homolog 2 | | 著者 | Miyazono, K, Ohno, Y, Ito, T, Tanokura, M. | | 登録日 | 2018-04-13 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Structural basis for receptor-regulated SMAD recognition by MAN1
Nucleic Acids Res., 46, 2018
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4YRL
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