PDB: 1334 件ウェブページステータス検索Chemie searchBIRD

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3RYZ	Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the Hydrophobic Wall of Carbonic Anhydrase 分子名称: Carbonic anhydrase 2, N-(2,2,3,3,4,4,4-heptafluorobutyl)-4-sulfamoylbenzamide, ZINC ION 著者 Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.W. 登録日 2011-05-11 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
3RYY	Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the Hydrophobic Wall of Carbonic Anhydrase 分子名称: Carbonic anhydrase 2, N-propyl-4-sulfamoylbenzamide, ZINC ION 著者 Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.W. 登録日 2011-05-11 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
3RYX	Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the Hydrophobic Wall of Carbonic Anhydrase 分子名称: Carbonic anhydrase 2, N-(2,2,3,3,3-pentafluoropropyl)-4-sulfamoylbenzamide, ZINC ION 著者 Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.W. 登録日 2011-05-11 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
3RYV	Carbonic Anhydrase complexed with N-ethyl-4-sulfamoylbenzamide 分子名称: Carbonic anhydrase 2, N-ethyl-4-sulfamoylbenzamide, ZINC ION 著者 Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.W. 登録日 2011-05-11 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
3RYJ	Carbonic Anhydrase complexed with 4-sulfamoyl-N-(2,2,2-trifluoroethyl)benzamide 分子名称: 4-sulfamoyl-N-(2,2,2-trifluoroethyl)benzamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.M. 登録日 2011-05-11 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
3RLD	Crystal structure of the Y7I mutant of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, SULFATE ION, ZINC ION 著者 Avvaru, B.S, Mikulski, R, McKenna, R. 登録日 2011-04-19 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II. Arch.Biochem.Biophys., 506, 2011
3RJ7	Human carbonic anhydrase II complexed with its inhibitor rhenium(I)triscarbonyl-cyclopentadienyl-carboxy-4-aminomethylbenzene-sulfonamide 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, MERCURIBENZOIC ACID, ... 著者 Spingler, B, Can, D, Alberto, R. 登録日 2011-04-15 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 [(Cp-R)M(CO)(3) ] (M=Re or (99m) Tc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX. Angew.Chem.Int.Ed.Engl., 51, 2012
3RGE	Crystal structure of the W5H mutant of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Domsic, J.F, Robbins, A.H, McKenna, R. 登録日 2011-04-08 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
3RG4	Crystal structure of the W5F mutant of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Domsic, J.F, Robbins, A.H, McKenna, R. 登録日 2011-04-07 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
3RG3	Crystal structure of the W5E mutant of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Domsic, J.F, Robbins, A.H, McKenna, R. 登録日 2011-04-07 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
3R17	hCarbonic anhydrase II bound to N-(2-fluoro.4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Biswas, S, McKenna, R. 登録日 2011-03-09 公開日 2011-05-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg.Med.Chem., 19, 2011
3R16	Human CAII bound to N-(4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Biswas, S, McKenna, R, Supuran, C.T. 登録日 2011-03-09 公開日 2011-05-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg.Med.Chem., 19, 2011
3QYK	Human Carbonic Anhydrase II complexed with triple ring benzene sulfonamide inhibitor 分子名称: 4-(7-methylpyrazolo[3',4':4,5]thiopyrano[2,3-b]pyridin-1(4H)-yl)benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Aggarwal, M, McKenna, R. 登録日 2011-03-03 公開日 2012-03-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.469 Å) 主引用文献 Human Carbonic Anhydrase II complexed with triple ring benzene sulfonamide inhibitor To be Published
3Q31	Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carbonic anhydrase, D-MALATE, ... 著者 Cuesta-Seijo, J.A, Borchert, M.S, Navarro-Poulsen, J.C, Schnorr, K.M, Leggio, L.L. 登録日 2010-12-21 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae To be Published
3PYK	Human Carbonic Anhydrase II as Host for Pianostool Complexes Bearing a Sulfonamide Anchor 分子名称: Carbonic anhydrase 2, METHYL MERCURY ION, SULFATE ION, ... 著者 Heinisch, T, Schirmer, T. 登録日 2010-12-13 公開日 2011-07-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Human Carbonic Anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor. Chem.Commun.(Camb.), 47, 2011
3PO6	Crystal structure of human carbonic anhydrase II with 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide 分子名称: (1R)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, (1S)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, ACETATE ION, ... 著者 Mader, P, Brynda, J, Gitto, R, Agnello, S, Ferro, S, De Luca, L, Vullo, D, Supuran, C.T, Chimirri, A. 登録日 2010-11-22 公開日 2011-04-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides. J.Med.Chem., 54, 2011
3PJJ	Synthetic Dimer of Human Carbonic Anhydrase II 分子名称: 1,1'-(oxydimethanediyl)dipyrrolidine-2,5-dione, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Kwant, R.L, Moustakas, D.T, Mack, E.T, Butte, M.J, Whitesides, G.W. 登録日 2010-11-10 公開日 2012-01-18 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 One Interface Stabilizes Linear Chains in All Polymorphs of Crystals of Human Carbonic Anhydrase II To be Published
3P5L	Human Carbonic Anhydrase complexed with sodium 4-cyano-4-phenylpiperidine-1-carbodithioate 分子名称: 4-cyano-4-phenylpiperidine-1-carbodithioic acid, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Aggarwal, M, McKenna, R. 登録日 2010-10-08 公開日 2011-10-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.498 Å) 主引用文献 Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem.Commun.(Camb.), 48, 2012
3P5A	Human Carbonic Anhydrase complexed with Sodium morpholinocarbodithioate 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... 著者 Aggarwal, M, McKenna, R. 登録日 2010-10-08 公開日 2011-10-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo J.Med.Chem., 55, 2012
3P58	Human Carbonic Anhydrase in complex with Benzyl (Methyl) Carbamodithoic Acid 分子名称: Carbonic anhydrase 2, ZINC ION, benzyl(methyl)carbamodithioic acid 著者 Aggarwal, M, McKenna, R. 登録日 2010-10-08 公開日 2011-10-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem.Commun.(Camb.), 48, 2012
3P55	Human carbonic anhydrase II in complex with p-(4-ferrocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-07 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
3P4V	Human carbonic anhydrase II in complex with (+)-Xylariamide A 分子名称: 3-chloro-N-[(2E)-4-methoxy-4-oxobut-2-enoyl]-L-tyrosine, Carbonic anhydrase 2, ZINC ION 著者 Hofmann, A, Nankervis, T, Davis, R. 登録日 2010-10-07 公開日 2011-04-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Natural Product-Based Phenols as Novel Probes for Mycobacterial and Fungal Carbonic Anhydrases. J.Med.Chem., 54, 2011
3P44	Human carbonic anhydrase II in complex with p-(4-ruthenocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-06 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
3P3J	Human carbonic anhydrase II in complex with p-(5-ruthenocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-05 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012
3P3H	Human carbonic anhydrase II in complex with p-(5-ferrocenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... 著者 Salmon, A.J. 登録日 2010-10-04 公開日 2011-09-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein crystal structures with ferrocene and ruthenocene-based enzyme inhibitors. Chem.Commun.(Camb.), 48, 2012

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