1ZFA
| GGA Duplex A-DNA | 分子名称: | 5'-D(*CP*CP*TP*CP*CP*GP*GP*AP*GP*G)-3', CALCIUM ION, SODIUM ION | 著者 | Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. | 登録日 | 2005-04-20 | 公開日 | 2005-05-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ZHM
| Crystal Structure of the Catalytic Domain of the Coagulation Factor XIa in Complex with Benzamidine (S434A-T475A-K437 Mutant) | 分子名称: | BENZAMIDINE, GLUTATHIONE, coagulation factor XI | 著者 | Jin, L, Pandey, P, Babine, R.E, Weaver, D.T, Abdel-Meguid, S.S, Strickler, J.E. | 登録日 | 2005-04-26 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors. Acta Crystallogr.,Sect.D, 61, 2005
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4N16
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4I71
| Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with a trypanocidal compound | 分子名称: | (2R,3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-2-(hydroxymethyl)pyrrolidine-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Giannese, F, Degano, M. | 登録日 | 2012-11-30 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor Acta Crystallogr.,Sect.D, 69, 2013
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1YYM
| crystal structure of F23, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), ... | 著者 | Huang, C.C, Stricher, F, Martin, L, Decker, J.M, Majeed, S, Barthe, P, Hendrickson, W.A, Robinson, J, Roumestand, C, Sodroski, J, Wyatt, R, Shaw, G.M, Vita, C, Kwong, P.D. | 登録日 | 2005-02-25 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure, 13, 2005
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4N8Z
| In situ lysozyme crystallized on a MiTeGen micromesh with benzamidine ligand | 分子名称: | BENZAMIDINE, CHLORIDE ION, Lysozyme C, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-10-18 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
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3WV3
| Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Collagenase 3, ... | 著者 | Oki, H, Tanaka, Y. | 登録日 | 2014-05-12 | 公開日 | 2014-09-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1′′ binding site. Bioorg.Med.Chem., 22, 2014
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1ZF9
| GGG Duplex A-DNA | 分子名称: | 5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', SODIUM ION | 著者 | Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. | 登録日 | 2005-04-20 | 公開日 | 2005-05-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3W7A
| Crystal Structure of azoreductase AzrC fin complex with sulfone-modified azo dye Acid Red 88 | 分子名称: | 4-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonic acid, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Yu, J, Ogata, D, Ooi, T, Yao, M. | 登録日 | 2013-02-27 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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4LU9
| Crystal structure of E.coli SbcD at 2.5 angstrom resolution | 分子名称: | Exonuclease subunit SbcD, GLYCEROL | 著者 | Liu, S, Tian, L.F, Yan, X.X, Liang, D.C. | 登録日 | 2013-07-25 | 公開日 | 2014-08-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repair. Acta Crystallogr.,Sect.D, 70, 2014
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5QDU
| PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000466a | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, ~{N},~{N},5,6-tetramethylthieno[2,3-d]pyrimidin-4-amine | 著者 | Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. | 登録日 | 2018-08-30 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | 主引用文献 | An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018
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1L4I
| Crystal Structure of the Periplasmic Chaperone SfaE | 分子名称: | SfaE PROTEIN | 著者 | Knight, S.D, Choudhury, D, Hultgren, S, Pinkner, J, Stojanoff, V, Thompson, A. | 登録日 | 2002-03-05 | 公開日 | 2002-06-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the S pilus periplasmic chaperone SfaE at 2.2 A resolution. Acta Crystallogr.,Sect.D, 58, 2002
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1UF5
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine | 分子名称: | 1,2-ETHANEDIOL, 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | 著者 | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | 登録日 | 2003-05-23 | 公開日 | 2004-06-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of C171A/V236A mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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4L19
| Matrix metalloproteinase-13 complexed with selective inhibitor compound Q1 | 分子名称: | 2-[(4-methylbenzyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one, CALCIUM ION, Collagenase 3, ... | 著者 | Minond, D, Spicer, T.P, Jiang, J, Taylor, A.B, Hart, P.J, Roush, W.R, Fields, G.B, Hodder, P.S. | 登録日 | 2013-06-02 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J.Med.Chem., 57, 2014
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1KZA
| Complex of MBP-C and Man-a13-Man | 分子名称: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-02-06 | 公開日 | 2002-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
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3OPF
| Crystal structure of TTHA0988 in space group P212121 | 分子名称: | GLYCEROL, Putative uncharacterized protein TTHA0988, SULFATE ION | 著者 | Jacques, D.A, Kuramitsu, S, Yokoyama, S, Trewhella, J, Guss, J.M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-09-01 | 公開日 | 2011-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase Acta Crystallogr.,Sect.D, 67, 2011
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2JCQ
| The hyaluronan binding domain of murine CD44 in a Type A complex with an HA 8-mer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD44 ANTIGEN, GLYCEROL | 著者 | Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G. | 登録日 | 2007-01-03 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction. Nat.Struct.Mol.Biol., 14, 2008
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1G0W
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3F64
| F17a-G lectin domain with bound GlcNAc(beta1-O)paranitrophenyl ligand | 分子名称: | 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, F17a-G | 著者 | Buts, L, De Boer, A, Olsson, J.D.M, Jonckheere, W, De Kerpel, M, De Genst, E, Guerardel, Y, Willaert, R, Wyns, L, Wuhrer, M, Oscarson, S, De Greve, H, Bouckaert, J. | 登録日 | 2008-11-05 | 公開日 | 2009-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli. Biology (Basel), 2, 2013
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1Y8J
| Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor | 分子名称: | 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Sahli, S, Frank, B, Schweizer, W.B, Diederich, F, Blum-Kaelin, D, Aebi, J.D, Bohm, H.J, Oefner, C, Dale, G.E. | 登録日 | 2004-12-13 | 公開日 | 2005-06-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-ray Crystal Structure Analysis HELV.CHIM.ACTA, 88, 2005
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3FBA
| Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with ligand | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, GERANYL DIPHOSPHATE, GLYCEROL, ... | 著者 | Hunter, W.N, Ramsden, N.L. | 登録日 | 2008-11-19 | 公開日 | 2009-08-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy J.Med.Chem., 52, 2009
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4IYR
| Crystal structure of full-length caspase-6 zymogen | 分子名称: | Caspase-6 | 著者 | Cao, Q, Wang, X.-J, Li, L.-F, Su, X.-D. | 登録日 | 2013-01-29 | 公開日 | 2014-01-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays. Acta Crystallogr.,Sect.D, 70, 2014
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1L6J
| Crystal structure of human matrix metalloproteinase MMP9 (gelatinase B). | 分子名称: | CALCIUM ION, Matrix metalloproteinase-9, ZINC ION | 著者 | Elkins, P.A, Ho, Y.S, Smith, W.W, Janson, C.A, D'Alessio, K.J, McQueney, M.S, Cummings, M.D, Romanic, A.M. | 登録日 | 2002-03-11 | 公開日 | 2002-07-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the C-terminally truncated human ProMMP9, a gelatin-binding matrix metalloproteinase. Acta Crystallogr.,Sect.D, 58, 2002
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1CS2
| NMR STRUCTURES OF B-DNA D(CTACTGCTTTAG).D(CTAAAGCAGTAG) | 分子名称: | 5'-d(*CP*TP*AP*AP*AP*GP*CP*AP*GP*TP*AP*G)-3', 5'-d(*CP*TP*AP*CP*TP*GP*CP*TP*TP*TP*AP*G)-3' | 著者 | Leporc, S, Mauffret, O, Tevanian, G, Lescot, E, Monnot, M, Fermandjian, S. | 登録日 | 1999-08-16 | 公開日 | 1999-08-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | An NMR and molecular modelling analysis of d(CTACTGCTTTAG). d(CTAAAGCAGTAG) reveals that the particular behaviour of TpA steps is related to edge-to-edge contacts of their base-pairs in the major groove Nucleic Acids Res., 27, 1999
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1UHY
| Crystal structure of d(GCGATAGC): the base-intercalated duplex | 分子名称: | 5'-D(*GP*(CBR)P*GP*AP*TP*AP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ... | 著者 | Kondo, J, Umeda, S.I, Fujita, K, Sunami, T, Takenaka, A. | 登録日 | 2003-07-13 | 公開日 | 2004-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | X-ray analyses of d(GCGAXAGC) containing G and T at X: the base-intercalated duplex is still stable even in point mutants at the fifth residue. J.Synchrotron Radiat., 11, 2004
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