PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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2OEW	Structure of ALIX/AIP1 Bro1 Domain 分子名称: Programmed cell death 6-interacting protein 著者 Fisher, R.D, Zhai, Q, Robinson, H, Hill, C.P. 登録日 2007-01-01 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding Cell(Cambridge,Mass.), 128, 2007
3TAV	Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus 分子名称: (2S)-2-hydroxybutanedioic acid, CHLORIDE ION, D-MALATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-08-04 公開日 2011-08-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4E2H	Crystal structure of the periplasmic domain of Shigella flexneri WzzB 分子名称: Chain length determinant protein 著者 Kalynych, S, Yao, D, Magee, J.D, Cygler, M. 登録日 2012-03-08 公開日 2012-03-28 最終更新日 2012-06-20 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators. J.Biol.Chem., 287, 2012
4E3L	Crystal structure of AmpC beta-lactamase in complex with a 3-chloro-4-tetrazolyl benzene sulfonamide boronic acid inhibitor 分子名称: Beta-lactamase, PHOSPHATE ION, [({[3-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid 著者 Eidam, O, Shoichet, B.K. 登録日 2012-03-09 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E2S	Crystal structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana in complex with its substrate, (S)-Ureidoglycine 分子名称: (2S)-amino(carbamoylamino)ethanoic acid, MANGANESE (II) ION, Ureidoglycine aminohydrolase 著者 Shin, I, Rhee, S. 登録日 2012-03-09 公開日 2012-04-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana J.Biol.Chem., 287, 2012
3TCR	Crystal structure of a molybdopterin biosynthesis protein from Mycobacterium abscessus 分子名称: Molybdopterin biosynthesis protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-08-09 公開日 2011-08-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4DX5	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop 分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ... 著者 Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. 登録日 2012-02-27 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
2NSC	Structures of and interactions between domains of trigger factor from Themotoga maritima 分子名称: Trigger factor 著者 Martinez-Hackert, E, Hendrickson, W.A. 登録日 2006-11-03 公開日 2007-03-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of and interactions between domains of trigger factor from Thermotoga maritima. Acta Crystallogr.,Sect.D, 63, 2007
3G20	Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ... 著者 Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J. 登録日 2009-01-30 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Calcium is essential for the major pseudopilin in the type 2 secretion system. J.Biol.Chem., 284, 2009
3G2O	Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-methionine (SAM) 分子名称: PCZA361.24, S-ADENOSYLMETHIONINE 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-01-31 公開日 2009-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chem.Biol., 16, 2009
2H3R	Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. 分子名称: Hypothetical protein BQLF2 著者 Benach, J, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Ho, C.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2006-05-23 公開日 2006-08-15 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published
3RM3	Crystal structure of monoacylglycerol lipase from Bacillus sp. H257 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Thermostable monoacylglycerol lipase 著者 Rengachari, S, Bezerra, G.A, Gruber, K, Oberer, M. 登録日 2011-04-20 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes. Biochim.Biophys.Acta, 1821, 2012
4ILK	Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MANGANESE (II) ION, Starvation sensing protein rspB, ... 著者 Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. 登録日 2012-12-31 公開日 2013-01-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH To be Published
2OIP	Crystal Structure of the S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis 分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Chain A, ... 著者 Martucci, W.E, Vargo, M.A. 登録日 2007-01-11 公開日 2007-07-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis Biochemistry, 46, 2007
2NVH	Determination of Solvent Content in Cavities in Interleukin-1 Using Experimentally-Phased Electron Density 分子名称: Interleukin-1 beta, SULFATE ION 著者 Quillin, M.L, Matthews, B.W. 登録日 2006-11-12 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Determination of solvent content in cavities in IL-1beta using experimentally phased electron density Proc.Natl.Acad.Sci.Usa, 103, 2006
3RQI	Crystal structure of a response regulator protein from Burkholderia pseudomallei with a phosphorylated aspartic acid, calcium ion and citrate 分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-04-28 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a response regulator protein from Burkholderia pseudomallei with a phosphorylated aspartic acid, calcium ion and citrate To be Published
3R9J	4.3A resolution structure of a MinD-MinE(I24N) protein complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division topological specificity factor, Septum site-determining protein minD 著者 Lovell, S, Battaile, K.P, Park, K.-T, Wu, W, Holyoak, T, Lutkenhaus, J. 登録日 2011-03-25 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 The Min Oscillator Uses MinD-Dependent Conformational Changes in MinE to Spatially Regulate Cytokinesis. Cell(Cambridge,Mass.), 146, 2011
4IBT	Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Diskin-Posner, Y, Eldar, A, Rozenberg, H, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IE4	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with 5-carboxy-8-hydroxyquinoline (IOX1) 分子名称: 8-hydroxyquinoline-5-carboxylic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, ... 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5048 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
3RSI	The structure of a putative enoyl-CoA hydratase/isomerase from Mycobacterium abscessus ATCC 19977 / DSM 44196 分子名称: GLYCEROL, IODIDE ION, Putative enoyl-CoA hydratase/isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-05-02 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2O02	Phosphorylation independent interactions between 14-3-3 and Exoenzyme S: from structure to pathogenesis 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, ExoS (416-430) peptide 著者 Ottmann, C, Yasmin, L, Weyand, M, Hauser, A.R, Wittinghofer, A, Hallberg, B. 登録日 2006-11-27 公開日 2007-11-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis Embo J., 26, 2007
2NZ8	N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1 分子名称: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein 著者 Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J. 登録日 2006-11-22 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation J.Mol.Biol., 368, 2007
4EBU	Crystal structure of a sugar kinase (Target EFI-502312) from Oceanicola granulosus, with bound AMP/ADP crystal form I 分子名称: 2-dehydro-3-deoxygluconokinase, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-03-24 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a sugar kinase (Target EFI-502312) from Oceanicola granulosus, with bound AMP/ADP crystal form I TO BE PUBLISHED
3RCD	HER2 Kinase Domain Complexed with TAK-285 分子名称: N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide, Receptor tyrosine-protein kinase erbB-2 著者 Aertgeerts, K, Skene, R, Sogabe, S. 登録日 2011-03-30 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold. J.Med.Chem., 54, 2011
3DMU	Crystal structure of Staphylococcal nuclease variant PHS T62K at cryogenic temperature 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease 著者 Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B, Benning, M, Isom, D. 登録日 2008-07-01 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant PHS T62K at cryogenic temperature To be Published

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