PDB: 2013 件ウェブページステータス検索Chemie searchBIRD

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6I7P	Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) 分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. 登録日 2018-11-16 公開日 2019-04-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.975 Å) 主引用文献 Supramolecular arrangement of the full-length Zika virus NS5. Plos Pathog., 15, 2019
2J7W	Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP 分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ... 著者 Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. 登録日 2006-10-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution. J.Virol., 81, 2007
5JJR	Dengue 3 NS5 protein with compound 29 分子名称: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ... 著者 Lescar, J, El Sahili, A. 登録日 2016-04-25 公開日 2016-07-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Plos Pathog., 12, 2016
5JJS	Dengue 3 NS5 protein with compound 27 分子名称: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-{[(1R,3R)-3-methoxycyclohexyl]sulfonyl}benzamide, DI(HYDROXYETHYL)ETHER, ... 著者 Lescar, J, El Sahili, A. 登録日 2016-04-25 公開日 2016-07-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Plos Pathog., 12, 2016
3AGP	Structure of viral polymerase form I 分子名称: CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... 著者 Takeshita, D, Tomita, K. 登録日 2010-04-06 公開日 2010-09-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts Proc.Natl.Acad.Sci.USA, 107, 2010
2P1D	Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine 分子名称: GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... 著者 Egloff, M.P, Benarooch, D, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2007-03-05 公開日 2007-03-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization EMBO J., 21, 2002
3AGQ	Structure of viral polymerase form II 分子名称: Elongation factor Ts, Elongation factor Tu 1, LINKER, ... 著者 Takeshita, D, Tomita, K. 登録日 2010-04-06 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts Proc.Natl.Acad.Sci.USA, 107, 2010
3AVX	Structure of viral RNA polymerase complex 5 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.406 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVV	Structure of viral RNA polymerase complex 3 分子名称: CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.119 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVY	Structure of viral RNA polymerase complex 6 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.616 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVT	Structure of viral RNA polymerase complex 1 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.607 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVU	Structure of viral RNA polymerase complex 2 分子名称: CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.907 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
3AVW	Structure of viral RNA polymerase complex 4 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... 著者 Takeshita, D, Tomita, K. 登録日 2011-03-08 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
6LKX	The structure of PRRSV helicase 分子名称: CITRIC ACID, GLYCEROL, RNA-dependent RNA polymerase, ... 著者 Shi, Y.J, Tong, X.H, Peng, G.Q. 登録日 2019-12-20 公開日 2020-05-27 最終更新日 2021-06-09 実験手法 X-RAY DIFFRACTION (2.998 Å) 主引用文献 Structural Characterization of the Helicase nsp10 Encoded by Porcine Reproductive and Respiratory Syndrome Virus. J.Virol., 94, 2020
6QW5	Structure and function of the toscana virus cap snatching endonuclease 分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... 著者 Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. 登録日 2019-03-05 公開日 2019-09-25 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (1.988 Å) 主引用文献 Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
6QVV	Structure and function of phenuiviridae cap snatching endonucleases 分子名称: GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... 著者 Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. 登録日 2019-03-05 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
6QW0	Structure and function of toscana virus cap snatching endonucleases 分子名称: GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... 著者 Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. 登録日 2019-03-05 公開日 2019-09-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
5K5M	Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ... 著者 Arora, R, Benson, T.E. 登録日 2016-05-23 公開日 2016-08-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling. Plos Pathog., 12, 2016
2J7U	Dengue virus NS5 RNA dependent RNA polymerase domain 分子名称: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ... 著者 Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. 登録日 2006-10-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution. J.Virol., 81, 2007
6OAR	Structure of the Kupe virus OTU bound to the C-terminal domain of sheep ISG15 分子名称: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine 著者 Dzimianski, J.V, Williams, I.L, Pegan, S.D. 登録日 2019-03-18 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.063 Å) 主引用文献 Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases. Plos One, 14, 2019
6OAT	Structure of the Ganjam virus OTU bound to sheep ISG15 分子名称: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine 著者 Dzimianski, J.V, Williams, I.L, Pegan, S.D. 登録日 2019-03-18 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases. Plos One, 14, 2019
7DFH	Structure of COVID-19 RNA-dependent RNA polymerase bound to ribavirin 分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... 著者 Li, Z, Zhou, Z, Yu, X. 登録日 2020-11-08 公開日 2021-11-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural basis for repurpose and design of nucleotide drugs for treating COVID-19 To Be Published
5EHG	DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF341 分子名称: 4-[3-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]phenyl]sulfonyloxybenzoic acid, RNA-directed RNA polymerase NS5, S-ADENOSYLMETHIONINE 著者 Barral, K, Bricogne, G, Sharff, A. 登録日 2015-10-28 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design. Eur.J.Med.Chem., 125, 2016
5TMH	Structure of Zika virus NS5 分子名称: GLYCEROL, Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Wang, B, Tan, X, Song, J. 登録日 2016-10-12 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.278 Å) 主引用文献 The structure of Zika virus NS5 reveals a conserved domain conformation. Nat Commun, 8, 2017
2WZL	The Structure of the N-RNA Binding Domain of the Mokola virus Phosphoprotein 分子名称: GLYCEROL, PHOSPHOPROTEIN 著者 Assenberg, R, Delmas, O, Ren, J, Vidalain, P, Verma, A, Larrous, F, Graham, S, Tangy, F, Grimes, J, Bourhy, H. 登録日 2009-11-30 公開日 2009-12-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structure of the N-RNA Binding Domain of the Mokola Virus Phosphoprotein J.Virol., 84, 2010

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