PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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3K9Y	Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5 分子名称: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... 著者 Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D. 登録日 2009-10-16 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. J.Mol.Biol., 396, 2010
6KZT	Crystal structure of cytochrome P450mel 107F1 with biaryl coupling reactivity 分子名称: Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE 著者 Hou, X.D, Rao, Y.J, Icyishaka, P, Li, C.X, Lou, J.L. 登録日 2019-09-25 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystallization and X-ray analysis of cytochrome P450mel 107F1 with biaryl coupling reactivity To Be Published
5L90	The crystal structure of substrate-free CYP109E1 from Bacillus megaterium at 2.55 Angstrom resolution 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
6L3A	Cytochrome P450 107G1 (RapN) with everolimus 分子名称: Cytochrome P450, Everolimus, PROTOPORPHYRIN IX CONTAINING FE 著者 Km, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
5L1T	X-ray Structure of M77S mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.082 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
6L8I	Crystal structure of CYP97A3 mutant S290D/W300L/S304V 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
6L39	Cytochrome P450 107G1 (RapN) 分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Kim, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. 登録日 2019-10-10 公開日 2020-09-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus. Arch.Biochem.Biophys., 692, 2020
6L8H	Crystal structure of CYP97C1 分子名称: Carotene epsilon-monooxygenase, chloroplastic, GLYCEROL, ... 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
5JL7	HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1): ANDROSTENEDIONE COMPLEX #3 分子名称: 4-ANDROSTENE-3-17-DIONE, Aromatase, PROTOPORPHYRIN IX CONTAINING FE 著者 Ghosh, D, Lo, J, Egbuta, C. 登録日 2016-04-26 公開日 2017-04-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Testosterone complex and non-steroidal ligands of human aromatase. J. Steroid Biochem. Mol. Biol., 2018
3MDT	Voriconazole complex of Cytochrome P450 46A1 分子名称: Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole 著者 Mast, N, Charvet, C, Pikuleva, I, Stout, C.D. 登録日 2010-03-30 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J.Biol.Chem., 285, 2010
6LDL	Crystal structure of CYP116B46-N(20-445) from Tepidiphilus thermophilus in complex with HEME 分子名称: BICINE, Cytochrome P450, GLYCEROL, ... 著者 Zhang, L.L, Xie, Z.Z, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2019-11-21 公開日 2020-10-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase. Nat Commun, 11, 2020
6L1B	Crystal Structure of P450BM3 with N-(3-cyclopentylpropanoyl)-L-pipecolyl-L-phenylalanine 分子名称: (2S)-2-[[(2S)-1-(3-cyclopentylpropanoyl)piperidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ... 著者 Shoji, O, Yonemura, K. 登録日 2019-09-28 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Systematic Evolution of Decoy Molecules for the Highly Efficient Hydroxylation of Benzene and Small Alkanes Catalyzed by Wild-Type Cytochrome P450BM3 Acs Catalysis, 10, 2020
6L8J	Crystal structure of CYP97A3 mutant S290D/W300L/S304V in complex with retinal 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic, ... 著者 Niu, G, Guo, Q, Liu, L. 登録日 2019-11-06 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
5LIE	Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with imidazole 分子名称: IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 126 著者 Levy, C, Munro, A.W, Leys, D. 登録日 2016-07-14 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J. Biol. Chem., 292, 2017
3JUS	Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with econazole 分子名称: 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), ... 著者 Strushkevich, N, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Usanov, S.A, Park, H, Structural Genomics Consortium (SGC) 登録日 2009-09-15 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of human CYP51 inhibition by antifungal azoles. J. Mol. Biol., 397, 2010
6L69	Crystal structure of CYP154C2 from Streptomyces avermitilis 分子名称: Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.H, Fushinobu, S. 登録日 2019-10-28 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis. Biochem.Biophys.Res.Commun., 522, 2020
5LI7	Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with 1-(3-(1H-imidazol-1-yl)propyl)-3-((3s,5s,7s)-adamantan-1-yl)urea 分子名称: 1-(1-adamantyl)-3-(3-imidazol-1-ylpropyl)urea, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 126 著者 Levy, C, Munro, A.W, Leys, D. 登録日 2016-07-14 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J. Biol. Chem., 292, 2017
3QZ1	Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21) 分子名称: (9beta)-17-hydroxypregn-4-ene-3,20-dione, PROTOPORPHYRIN IX CONTAINING FE, Steroid 21-hydroxylase 著者 Zhao, B, Waterman, M.R. 登録日 2011-03-04 公開日 2012-01-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21) To be Published
5JKV	HUMAN PLACENTAL AROMATASE CYTOCHROME P450 (CYP19A1) AT 2.75 ANGSTROM WITH BOUND POLYETHYLENE GLYCOL 分子名称: 4-ANDROSTENE-3-17-DIONE, Aromatase, PENTAETHYLENE GLYCOL, ... 著者 Ghosh, D, Lo, J, Egbuta, C. 登録日 2016-04-26 公開日 2017-04-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Testosterone complex and non-steroidal ligands of human aromatase. J. Steroid Biochem. Mol. Biol., 2018
5JQV	Crystal structure of Cytochrome P450 BM3 heme domain T269V/L272W/L322I/A406S (WIVS) variant with iron(III) deuteroporphyrin IX bound 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, FE(III) DEUTEROPORPHYRIN IX 著者 Reynolds, E.W, McHenry, M.W, Cannac, F, Gober, J.G, Snow, C.D, Brustad, E.M. 登録日 2016-05-05 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 An Evolved Orthogonal Enzyme/Cofactor Pair. J.Am.Chem.Soc., 138, 2016
3P6X	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C8-Dans 分子名称: Camphor 5-monooxygenase, N-[8-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)octyl]-3-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]propanamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-10-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C8-Dans To be Published
5JTD	Crystal structure of the Ru(bpy)2PhenA functionalized P450 BM3 L407C heme domain mutant in complex with DMSO. 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Kloos, M. 登録日 2016-05-09 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies. Biochim.Biophys.Acta, 1864, 2016
3P6U	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C6-Dans 分子名称: Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-10-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-C6-Dans To be Published
3P6V	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog 3Et-AdaC1-Etg-Boc 分子名称: Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-10-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog 3Et-AdaC1-Etg-Boc To be Published
6M4S	Crystal Structure Analysis of the cytochrome P450 CYP-Sb21 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cytochrome P450 hydroxylase sb21, ... 著者 Li, F.W, Li, S.Y. 登録日 2020-03-09 公開日 2021-02-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana . Synth Syst Biotechnol, 5, 2020

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