PDB: 35463 件ウェブページステータス検索Chemie searchBIRD

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9FA4	Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 1) 分子名称: Integrator complex subunit 10, Integrator complex subunit 13, Integrator complex subunit 14, ... 著者 Razew, M, Galej, W.P. 登録日 2024-05-10 公開日 2024-06-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 84, 2024
9FA7	Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 3) 分子名称: Integrator complex subunit 10, Integrator complex subunit 13, Integrator complex subunit 14, ... 著者 Razew, M, Galej, W.P. 登録日 2024-05-10 公開日 2024-06-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 84, 2024
9ICD	CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES 分子名称: ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hurley, J.H, Dean, A.M, Koshland Jr, D.E, Stroud, R.M. 登録日 1991-07-29 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes. Biochemistry, 30, 1991
6PBK	Archaellum periplasmic stator protein complex FlaF and FlaG from Sulfolobus acidocaldarius 分子名称: 1,2-ETHANEDIOL, Conserved flagellar protein F, DI(HYDROXYETHYL)ETHER, ... 著者 Tsai, C.-L, Tainer, J.A. 登録日 2019-06-14 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility. Nat Microbiol, 5, 2020
6PIV	Crystal structure of HCV NS3/4A D168A protease in complex with P4-7 (NR03-77) 分子名称: (1R,3r,5S)-bicyclo[3.1.0]hexan-3-yl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, 1,2-ETHANEDIOL, NS3/4A protease, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2019-06-27 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
6PJ0	Crystal structure of HCV NS3/4A D168A protease in complex with P4-5 (NR01-97) 分子名称: 1,2-ETHANEDIOL, 1-ethylcyclopentyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4 Aprotease, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2019-06-27 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
6PIW	Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67) 分子名称: 1,2-ETHANEDIOL, NS3/A4 protease, ZINC ION, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2019-06-27 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
6PJ1	Crystal structure of HCV NS3/4A D168A protease in complex with P4-4(AJ-74) 分子名称: 1,2-ETHANEDIOL, 1-methylcyclopentyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4A protease, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2019-06-27 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
6P8H	Crystal structure of CDK4 in complex with CyclinD1 and P21 分子名称: Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1, G1/S-specific cyclin-D1 著者 Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. 登録日 2019-06-07 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science, 366, 2019
1WVH	Crystal structure of tensin1 PTB domain 分子名称: Tensin 著者 McCleverty, C.J, Liddington, R.C. 登録日 2004-12-15 公開日 2005-12-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions. Protein Sci., 16, 2007
1WDZ	Crystal structure of RCB domain of IRSp53 分子名称: insulin receptor substrate p53 著者 Murayama, K, Suetsugu, S, Seto, A, Shirouzu, M, Takenawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-21 公開日 2005-06-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Crystal structure of RCB domain of IRSp53 TO BE PUBLISHED
6PIZ	Crystal structure of HCV NS3/4A D168A protease in complex with P4-1 (NR02-24) 分子名称: 1,2-ETHANEDIOL, 1-methylcyclopropyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, GLYCEROL, ... 著者 Zephyr, J, Schiffer, C.A. 登録日 2019-06-27 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
1WY4	Chicken villin subdomain HP-35, K65(NLE), N68H, pH5.1 分子名称: IODIDE ION, SODIUM ION, Villin 著者 Chiu, T.K, Kubelka, J, Herbst-Irmer, R, Eaton, W.A, Hofrichter, J, Davies, D.R. 登録日 2005-02-04 公開日 2005-05-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High-resolution x-ray crystal structures of the villin headpiece subdomain, an ultrafast folding protein. Proc.Natl.Acad.Sci.Usa, 102, 2005
1WY3	Chicken villin subdomain HP-35, K65(NLE), N68H, pH7.0 分子名称: Villin 著者 Chiu, T.K, Kubelka, J, Herbst-Irmer, R, Eaton, W.A, Hofrichter, J, Davies, D.R. 登録日 2005-02-04 公開日 2005-05-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 High-resolution x-ray crystal structures of the villin headpiece subdomain, an ultrafast folding protein. Proc.Natl.Acad.Sci.Usa, 102, 2005
1X5N	Solution structure of the second PDZ domain of harmonin protein 分子名称: Harmonin 著者 Qin, X.R, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-16 公開日 2005-11-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second PDZ domain of harmonin protein To be published
1X9J	Structure of butyrate kinase 2 reveals both open- and citrate-induced closed conformations: implications for substrate-induced fit conformational changes 分子名称: CITRIC ACID, GLYCEROL, PHOSPHATE ION, ... 著者 Diao, J.S, Sanders, D.A, Hasson, M.S. 登録日 2004-08-21 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of butyrate kinase 2 reveals both open and closed conformations of the two domains: implications for substrate-induced changes To be Published
5L9V	HIF prolyl hydroxylase 2 (PHD2-R281C/P317C) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-1) 分子名称: Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-11 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.829 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5LAS	HIF prolyl hydroxylase 2 (PHD2-R281C/P317C/R396T) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-3) 分子名称: Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-14 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
1W3W	The 2.1 Angstroem resolution structure of annexin A8 分子名称: ANNEXIN A8, CALCIUM ION 著者 Rety, S, Sopkova-De Oliveira Santos, J, Renouard, M, Lewit-Bentley, A. 登録日 2004-07-20 公開日 2005-01-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The Crystal Structure of Annexin A8 is Similar to that of Annexin A3 J.Mol.Biol., 345, 2005
5L9B	HIF PROLYL HYDROXYLASE 2 (PHD2/ EGLN1) IN COMPLEX WITH 2-OXOGLUTARATE (2OG) AND HIF-1ALPHA CODD (556-574) 分子名称: 2-OXOGLUTARIC ACID, Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-10 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5LA9	HIF prolyl hydroxylase 2 (PHD2-R281C/V314C) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-2) 分子名称: Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-14 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.813 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
1VMC	STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) 分子名称: Stromal cell-derived factor 1 著者 Gozansky, E.K, Clore, G.M. 登録日 2004-09-20 公開日 2005-03-01 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha. J.Mol.Biol., 345, 2005
1W45	The 2.5 Angstroem structure of the K16A mutant of annexin A8, which has an intact N-terminus. 分子名称: ANNEXIN A8 著者 Rety, S, Sopkova-de Oliveira Santos, J, Raguenes-Nicol, C, Dreyfuss, L, Blondeau, K, Hofbauerova, K, Renouard, M, Russo-Marie, F, Lewit-Bentley, A. 登録日 2004-07-22 公開日 2005-01-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 The Crystal Structure of Annexin A8 is Similar to that of Annexin A3 J.Mol.Biol., 345, 2005
1VOM	COMPLEX BETWEEN DICTYOSTELIUM MYOSIN AND MGADP AND VANADATE AT 1.9A RESOLUTION 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ... 著者 Rayment, I, Smith, C.A. 登録日 1995-11-09 公開日 1996-12-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution. Biochemistry, 35, 1996
1YIB	Crystal Structure of the Human EB1 C-terminal Dimerization Domain 分子名称: Microtubule-associated protein RP/EB family member 1 著者 Slep, K.C, Rogers, S.L, Elliott, S.L, Ohkura, H, Kolodziej, P.A, Vale, R.D. 登録日 2005-01-11 公開日 2005-03-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end J.Cell Biol., 168, 2005

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