3WUW
 
 | | KIR3DL1 in complex with HLA-B*57:01.I80T | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Vivian, J.P, Rossjohn, J. | | 登録日 | 2014-05-06 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity
J.Immunol., 192, 2014
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4PJH
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7DYN
 | | Phosphorylation of MHC I peptide | | 分子名称: | ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | | 著者 | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J. | | 登録日 | 2021-01-22 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules.
Iscience, 25, 2022
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2NY4
 | | HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | 著者 | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | | 登録日 | 2006-11-20 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
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6J1V
 | | The structure of HLA-A*3003/RT313 | | 分子名称: | Beta-2-microglobulin, HLA-A*3003, RT313 | | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | | 登録日 | 2018-12-29 | | 公開日 | 2019-09-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides.
Front Immunol, 10, 2019
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5SWQ
 | | Crystal Structure of HLA-A*0201 in complex with NA231, an influenza epitope | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | 著者 | Josephs, T.M, Rossjohn, J, Gras, S. | | 登録日 | 2016-08-08 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct alpha beta T Cell Receptor Signatures.
J.Biol.Chem., 291, 2016
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2IPT
 | | PFA1 Fab Fragment | | 分子名称: | ACETAMIDE, IgG2a Fab fragment Heavy Chain, IgG2a Fab fragment Light Chain Kappa | | 著者 | Gardberg, A.S, Dealwis, C. | | 登録日 | 2006-10-12 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
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6MFG
 | | HLA-DQ2-glia-alpha1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... | | 著者 | Petersen, J, Ciacchi, L, Rossjohn, J. | | 登録日 | 2018-09-10 | | 公開日 | 2018-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.
J. Biol. Chem., 294, 2019
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4PV9
 | | Crystal Structure of H2Kb-Q600V complex | | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Twist, K.-A, Rossjohn, J, Gras, S. | | 登録日 | 2014-03-15 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes.
J.Immunol., 192, 2014
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7WBG
 | | BF2*1901/RY8 | | 分子名称: | ARG-ARG-ARG-GLU-GLN-THR-ASP-TYR, Beta-2-microglobulin, MHC class I alpha chain 2 | | 著者 | Liu, W.J. | | 登録日 | 2021-12-16 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek's Disease.
J Immunol., 210, 2023
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4PJ5
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6VB3
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7K81
 | | KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ... | | 著者 | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | | 登録日 | 2020-09-24 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
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2C1P
 | | Fab-fragment of enantioselective antibody complexed with finrozole | | 分子名称: | 4-[(1S,2R)-3-(4-FLUOROPHENYL)-2-HYDROXY-1-(1H-1,2,4-TRIAZOL-1-YL)PROPYL]BENZONITRILE, IGH-4 PROTEIN, IGK-C PROTEIN | | 著者 | Parkkinen, T, Nevanen, T.K, Koivula, A, Rouvinen, J. | | 登録日 | 2005-09-19 | | 公開日 | 2006-01-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of an Enantioselective Fab-Fragment in Free and Complex Forms.
J.Mol.Biol., 357, 2006
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6MJ4
 | | Crystal structure of MCD1D/INKTCR TERNARY COMPLEX bound to glycolipid (XXW) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zajonc, D.M, Bitra, A, Janssens, J. | | 登録日 | 2018-09-20 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
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8RHQ
 | | Crystal structure of HLA-A*11:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984) | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S. | | 登録日 | 2023-12-16 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
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6MP0
 | | Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with the TRP1-M9 peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TRP1-M9 peptide, Beta-2-microglobulin,H-2 class I histocompatibility antigen, ... | | 著者 | Clancy-Thompson, E, Devlin, C.A, Birnbaum, M.E, Dougan, S.K. | | 登録日 | 2018-10-05 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+T Cell-Effector Responses.
Cancer Immunol Res, 6, 2018
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7P3E
 | | MHC I A02 Allele presenting YLQLRTFLL | | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ... | | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | | 登録日 | 2021-07-07 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
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4LNR
 | | The structure of HLA-B*35:01 in complex with the peptide (RPQVPLRPMTY) | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Cheng, H, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2013-07-12 | | 公開日 | 2014-07-23 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.
J.Biol.Chem., 289, 2014
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5D7I
 | | Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR | | 分子名称: | Beta-2-microglobulin, GLYCEROL, M33.64 TCR Alpha Chain, ... | | 著者 | Keller, A.N, Woolley, R.E, Rossjohn, J. | | 登録日 | 2015-08-14 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
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6C99
 | | Crystal structure of FcRn bound to UCB-303 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CITRIC ACID, ... | | 著者 | Fox III, D, Abendroth, J, Porter, J, Deboves, H. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
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2G9H
 | | Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | | 著者 | Fernandez, M.M, Guan, R, Malchiodi, E.L, Mariuzza, R.A. | | 登録日 | 2006-03-06 | | 公開日 | 2006-07-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule.
J.Biol.Chem., 281, 2006
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1D5M
 | | X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE AND SEB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Swain, A.L, Crowther, R, Kammlott, U. | | 登録日 | 1999-10-07 | | 公開日 | 2000-06-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
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1D6V
 | | CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION | | 分子名称: | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), ... | | 著者 | Mundorff, E.C, Hanson, M.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1999-10-15 | | 公開日 | 2000-02-09 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
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6C97
 | | Crystal structure of FcRn at pH3 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, IgG receptor FcRn large subunit p51 | | 著者 | Fox III, D, Fairman, J.W. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
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