PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

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6DWY	Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+ 分子名称: CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ... 著者 Dyda, F, Hickman, A.B. 登録日 2018-06-28 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018
1V6U	Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 2(2)-alpha-L-arabinofuranosyl-xylobiose 分子名称: alpha-D-xylopyranose, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ... 著者 Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. 登録日 2003-12-04 公開日 2004-04-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86 J.Biol.Chem., 279, 2004
6DU7	Glutathione reductase from Streptococcus pneumoniae 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, THIOCYANATE ION 著者 Maher, M.J, Sikanyika, M. 登録日 2018-06-19 公開日 2019-01-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 The structure and activity of the glutathione reductase from Streptococcus pneumoniae. Acta Crystallogr F Struct Biol Commun, 75, 2019
2DAR	Solution structure of first LIM domain of Enigma-like PDZ and LIM domains protein 分子名称: PDZ and LIM domain protein 5, ZINC ION 著者 Niraula, T.N, Muto, Y, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-12-14 公開日 2006-12-12 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of first LIM domain of Enigma-like PDZ and LIM domains protein To be Published
1XZ9	Structure of AF-6 PDZ domain 分子名称: Afadin 著者 Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H. 登録日 2004-11-12 公開日 2005-11-15 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
5EYP	TUBULIN-DARPIN COMPLEX 分子名称: DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Ahmad, S, Knossow, M, Gigant, B. 登録日 2015-11-25 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep, 6, 2016
1UML	Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624 分子名称: 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION 著者 Kinoshita, T. 登録日 2003-10-03 公開日 2004-09-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47, 2004
5GHW	Crystal structure of broad neutralizing antibody 10E8 with long epitope bound 分子名称: Endogenous retrovirus group K member 8 Env polyprotein, FAB 10E8 HEAVY CHAIN, FAB 10E8 LIGHT CHAIN, ... 著者 Caaveiro, J.M.M, Rujas, E, Morante, K, Nieva, J.L, Tsumoto, K. 登録日 2016-06-21 公開日 2016-11-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface Sci Rep, 6, 2016
1Y6B	Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor 分子名称: N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE, Vascular endothelial growth factor receptor 2 著者 Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A. 登録日 2004-12-05 公開日 2005-06-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J.Med.Chem., 48, 2005
6E1A	Menin bound to M-89 分子名称: (1S,2R)-2-[(4S)-2-methyl-4-{1-[(1-{4-[(pyridin-4-yl)sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}-1,2,3,4-tetrahydroisoquinolin-4-yl]cyclopentyl methylcarbamate, Menin, praseodymium triacetate 著者 Stuckey, J.A. 登録日 2018-07-09 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction. J.Med.Chem., 62, 2019
1SVH	Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8 分子名称: (3R,4S)-N-(4-{TRANS-2-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-PHENYL]-VINYL}-AZEPAN-3-YL)-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... 著者 Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. 登録日 2004-03-29 公開日 2005-03-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
2E5C	Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase 著者 Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. 登録日 2006-12-20 公開日 2007-12-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
4DG3	Crystal structure of R336A mutant of cAMP-dependent protein kinase with unphosphorylated turn motif. 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Steichen, J.M, Yang, J, Taylor, S.S. 登録日 2012-01-24 公開日 2013-02-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Turn motif phosphorylation regulates processing of cAMP-dependent protein kinase To be Published
4DH5	Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ADP, Phosphate, and IP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
5CPT	Disproportionating enzyme 1 from Arabidopsis - beta cyclodextrin soak 分子名称: 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ... 著者 O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M. 登録日 2015-07-21 公開日 2015-11-04 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). J.Biol.Chem., 290, 2015
1Z68	Crystal Structure Of Human Fibroblast Activation Protein alpha 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Aertgeerts, K, Levin, I, Shi, L, Prasad, G.S, Zhang, Y, Kraus, M.L, Salakian, S, Snell, G.P, Sridhar, V, Wijnands, R, Tennant, M.G. 登録日 2005-03-21 公開日 2005-04-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha. J.Biol.Chem., 280, 2005
1ZBD	STRUCTURAL BASIS OF RAB EFFECTOR SPECIFICITY: CRYSTAL STRUCTURE OF THE SMALL G PROTEIN RAB3A COMPLEXED WITH THE EFFECTOR DOMAIN OF RABPHILIN-3A 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RABPHILIN-3A, ... 著者 Ostermeier, C, Brunger, A.T. 登録日 1998-11-06 公開日 1999-04-02 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. Cell(Cambridge,Mass.), 96, 1999
4ASH	Crystal structure of the NS6 protease from murine norovirus 1 分子名称: NS6 PROTEASE 著者 Leen, E.N, Baeza, G, Curry, S. 登録日 2012-05-01 公開日 2012-05-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.578 Å) 主引用文献 Structure of a Murine Norovirus Ns6 Protease-Product Complex Revealed by Adventitious Crystallisation. Plos One, 7, 2012
6E29	Crystal structure of Myceliophteria_thermophila Cps50 (Swd1) beta-propeller domain 分子名称: SWD1-like protein 著者 Joshi, M, Yang, Y, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-10 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.818 Å) 主引用文献 Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex. Cell, 174, 2018
2AOQ	Crystal structure of MutH-unmethylated DNA complex 分子名称: 5'-D(*GP*CP*AP*TP*GP*AP*TP*CP*AP*TP*GP*C)-3', CALCIUM ION, DNA mismatch repair protein mutH 著者 Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. 登録日 2005-08-13 公開日 2005-10-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
5ISM	Human DPP4 in complex with a novel 5,5,6-tricyclic pyrrolidine inhibitor 分子名称: (2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-a]pyrimidin-8(9H)-yl)oxan-3-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G. 登録日 2016-03-15 公開日 2016-05-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
5C0X	Structure of a 12-subunit nuclear exosome complex bound to structured RNA 分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... 著者 Makino, D.L, Conti, E. 登録日 2015-06-12 公開日 2015-08-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.812 Å) 主引用文献 RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
2B2D	RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid 分子名称: 5'-R(*AP*UP*GP*CP*AP*UP*GP*UP*CP*UP*AP*AP*GP*AP*CP*AP*GP*CP*AP*U)-3', Coat protein 著者 Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G. 登録日 2005-09-19 公開日 2006-05-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2 Structure, 14, 2006
5C6P	protein C 分子名称: (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D 著者 Lu, M. 登録日 2015-06-23 公開日 2015-09-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
3J4Q	Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy 分子名称: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit 著者 Reichow, S.L, Gonen, T. 登録日 2013-09-25 公開日 2013-11-13 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife, 2, 2013

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