PDB: 23413 件ウェブページステータス検索Chemie searchBIRD

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8P63	S. cerevisiae consensus-sCMGE on ssDNA after DNA replication initiation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... 著者 Henrikus, S.S, Willhoft, O. 登録日 2023-05-25 公開日 2024-05-29 最終更新日 2024-08-28 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Unwinding of a eukaryotic origin of replication visualized by cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
8P62	S. cerevisiae ssDNA-sCMGE after DNA replication initiation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... 著者 Henrikus, S.S, Willhoft, O. 登録日 2023-05-25 公開日 2024-05-29 最終更新日 2024-08-28 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Unwinding of a eukaryotic origin of replication visualized by cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
3UF8	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with a G95A surface mutation from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-10-31 公開日 2011-11-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4NHM	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: GLYCEROL, MANGANESE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ... 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
5GAS	Thermus thermophilus V/A-ATPase, conformation 2 分子名称: Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... 著者 Schep, D.G, Zhao, J, Rubinstein, J.L. 登録日 2016-02-05 公開日 2016-03-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (9.5 Å) 主引用文献 Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance. Proc.Natl.Acad.Sci.USA, 113, 2016
3UQA	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-19 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
5HJZ	Structure of M. tuberculosis MazF-mt1 (Rv2801c) in complex with RNA 分子名称: Endoribonuclease MazF9, RNA (5'-R(*CP*AP*UP*C)-D(P*U)-R(P*AP*CP*CP*UP*GP*A)-3') 著者 Yen, T.J, Brennan, R.G. 登録日 2016-01-13 公開日 2017-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.976 Å) 主引用文献 Structure of M. tuberculosis MazF-mt1 (Rv2801c) in complex with RNA To Be Published
5HK3	Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA 分子名称: DNA (5'-D(*AP*GP*UP*CP*UP*CP*CP*UP*UP*UP*C)-3'), Endoribonuclease MazF6 著者 Yen, T.J, Brennan, R.G. 登録日 2016-01-13 公開日 2017-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA To Be Published
5HKC	Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA 分子名称: Endoribonuclease MazF6, RNA (5'-R(*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*A)-3') 著者 Yen, T.J, Brennan, R.G. 登録日 2016-01-14 公開日 2017-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA To Be Published
8QEB	S. cerevisia Niemann-Pick type C protein NCR1 in GDN at pH 7.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ERGOSTEROL, ... 著者 Frain, K.M, Dedic, E, Nel, L, Olesen, E, Stokes, D, Panyella Pedersen, B. 登録日 2023-08-31 公開日 2023-10-18 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation. Proc.Natl.Acad.Sci.USA, 121, 2024
4NZU	Crystal structure of the primary monoclonal antibody 13PL Fab' from a multiple myeloma patient 分子名称: 13PL heavy chain, 13PL light chain, ACETATE ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2013-12-12 公開日 2014-02-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science, 343, 2014
8QED	S. cerevisia Niemann-Pick type C protein NCR1 in LMNG at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ERGOSTEROL, NPC intracellular sterol transporter 1-related protein 1, ... 著者 Frain, K.M, Nel, L, Dedic, E, Olesen, E, Stokes, D, Panyella Pedersen, B. 登録日 2023-08-31 公開日 2023-10-18 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation. Proc.Natl.Acad.Sci.USA, 121, 2024
8QEE	S. cerevisia Niemann-Pick type C protein NCR1 in Peptidisc at pH 7.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... 著者 Frain, K.M, Dedic, E, Nel, L, Olesen, E, Stokes, D, Panyella Pedersen, B. 登録日 2023-08-31 公開日 2023-10-18 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (2.43 Å) 主引用文献 Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation. Proc.Natl.Acad.Sci.USA, 121, 2024
8QEC	S. cerevisia Niemann-Pick type C protein NCR1 in GDN at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, CHOLESTEROL HEMISUCCINATE, ... 著者 Frain, K.M, Dedic, E, Nel, L, Olesen, E, Stokes, D, Panyella Pedersen, B. 登録日 2023-08-31 公開日 2023-10-18 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation. Proc.Natl.Acad.Sci.USA, 121, 2024
4O1L	Human Adenosine Kinase in complex with inhibitor 分子名称: 5-ethynyl-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Adenosine kinase, MAGNESIUM ION 著者 Brynda, J, Dostal, J, Pichova, I, Hodcek, M. 登録日 2013-12-16 公開日 2014-11-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides J.Med.Chem., 57, 2014
5Y63	Crystal structure of Enterococcus faecalis AhpC 分子名称: Alkyl hydroperoxide reductase, C subunit 著者 Pan, A, Balakrishna, A.M, Grueber, G. 登録日 2017-08-10 公開日 2017-12-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Atomic structure and enzymatic insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C Free Radic. Biol. Med., 115, 2017
5GAR	Thermus thermophilus V/A-ATPase, conformation 1 分子名称: Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... 著者 Schep, D.G, Zhao, J, Rubinstein, J.L. 登録日 2016-02-05 公開日 2016-03-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance. Proc.Natl.Acad.Sci.USA, 113, 2016
2LJL	NMR structure of Hsp12 in the presence of DPC 分子名称: 12 kDa heat shock protein 著者 Singarapu, K, Markley, J, Center for Eukaryotic Structural Genomics (CESG) 登録日 2011-09-20 公開日 2011-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally alpha-helical. J.Biol.Chem., 286, 2011
5HK0	Crystal structure of M. tuberculosis MazF-mt3 (Rv1991c) in complex with RNA 分子名称: Endoribonuclease MazF6, RNA (5'-R(*AP*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*UP*UP*C)-3') 著者 Yen, T.J, Brennan, R.G. 登録日 2016-01-13 公開日 2017-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of M. tuberculosis MazF-mt3 (Rv1991c) in complex with RNA To Be Published
5TGM	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... 著者 Melnikov, S, Mailliot, J, Yusupov, M. 登録日 2016-09-28 公開日 2017-01-18 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5MTQ	Crystal structure of M. tuberculosis InhA inhibited by PT511 分子名称: 2-[4-[(4-cyclohexyl-1,2,3-triazol-1-yl)methyl]-2-oxidanyl-phenoxy]benzenecarbonitrile, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. 登録日 2017-01-10 公開日 2017-02-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017
5UAQ	Escherichia coli RNA polymerase RpoB H526Y mutant 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. 登録日 2016-12-19 公開日 2017-01-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
6F9H	Crystal structure of Barley Beta-Amylase complexed with 4-S-alpha-D-glucopyranosyl-(1,4-dideoxy-4-thio-nojirimycin) 分子名称: 1,4-dideoxy-4-thio-nojirimycin, Beta-amylase, CHLORIDE ION, ... 著者 Moncayo, M.A, Rodrigues, L.L, Stevenson, C.E.M, Ruzanski, C, Rejzek, M, Lawson, D.M, Angulo, J, Field, R.A. 登録日 2017-12-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Synthesis, biological and structural analysis of prospective glycosyl-iminosugar prodrugs: impact on germination To be published
5UAJ	Escherichia coli RNA polymerase RpoB S531L mutant 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. 登録日 2016-12-19 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.915 Å) 主引用文献 Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
8CLV	Zearalenone lactonase of Rhodococcus erythropolis in complex with hydrolyzed zearalenone 分子名称: 2,4-dihydroxy-6-[(1E,10S)-10-hydroxy-6-oxoundec-1-en-1-yl]benzoic acid, Zearalenone lactonase 著者 Puehringer, D. 登録日 2023-02-17 公開日 2024-02-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone. Acs Catalysis, 14, 2024

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