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3E42
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BU of 3e42 by Molmil
Q138F HincII bound to GTCGAC and Ca2+ (cocrystallized)
分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DCP*DGP*DAP*DCP*DCP*DGP*DGP*DC)-3', CALCIUM ION, SODIUM ION, ...
著者Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M.
登録日2008-08-08
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献DNA distortion and specificity in a sequence-specific endonuclease.
J.Mol.Biol., 383, 2008
4P3K
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BU of 4p3k by Molmil
Structure of ancestral PyrR protein (PLUMPyrR)
分子名称: Ancestral PyrR protein (Plum), PENTAETHYLENE GLYCOL, SODIUM ION, ...
著者Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A.
登録日2014-03-08
公開日2014-12-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of oligomeric state through allosteric pathways that mimic ligand binding.
Science, 346, 2014
3FYH
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BU of 3fyh by Molmil
Recombinase in complex with ADP and metatungstate
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ...
著者Li, Y, He, Y, Luo, Y.
登録日2009-01-22
公開日2009-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor.
Biochemistry, 48, 2009
2W1S
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BU of 2w1s by Molmil
Unique ligand binding specificity of a family 32 Carbohydrate-Binding Module from the Mu toxin produced by Clostridium perfringens
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, HYALURONOGLUCOSAMINIDASE, ...
著者Ficko-Blean, E, Boraston, A.B.
登録日2008-10-20
公開日2009-05-05
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh.
J.Mol.Biol., 390, 2009
3G1N
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BU of 3g1n by Molmil
Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1
分子名称: E3 ubiquitin-protein ligase HUWE1, SODIUM ION
著者Walker, J.R, Qiu, L, Li, Y, Davis, T, Tempel, W, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-01-30
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Hect Domain of Human HUWE1/MULE
To be Published
4OQ4
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BU of 4oq4 by Molmil
Crystal Structure of E18A Human DJ-1
分子名称: Protein DJ-1, SODIUM ION
著者Prahlad, J, Hauser, D.N, Milkovic, N.M, Cookson, M.R, Wilson, M.A.
登録日2014-02-07
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers.
J Neurochem, 130, 2014
3FZQ
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BU of 3fzq by Molmil
Crystal structure of putative haloacid dehalogenase-like hydrolase (YP_001086940.1) from Clostridium difficile 630 at 2.10 A resolution
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Putative hydrolase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-01-26
公開日2009-02-10
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of putative haloacid dehalogenase-like hydrolase (YP_001086940.1) from Clostridium difficile 630 at 2.10 A resolution
To be published
4OWE
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BU of 4owe by Molmil
PtCl6 binding to HEWL
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者Tanley, S.W.M, Starkey, V.L, Lamplough, L, Kaenket, S, Helliwell, J.R.
登録日2014-01-31
公開日2014-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15.
Acta Crystallogr.,Sect.F, 70, 2014
3CYM
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BU of 3cym by Molmil
Crystal structure of protein BAD_0989 from Bifidobacterium adolescentis
分子名称: GLYCEROL, SODIUM ION, Uncharacterized protein BAD_0989
著者Patskovsky, Y, Ozyurt, S, Freeman, J, Chang, S, Bain, K, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-04-25
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of protein BAD_0989 from Bifidobacterium adolescentis.
To be Published
4PIG
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BU of 4pig by Molmil
Crystal structure of the ubiquitin K11S mutant
分子名称: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Loll, P.J, Xu, P.J, Schmidt, J, Melideo, S.L.
登録日2014-05-08
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Enhancing ubiquitin crystallization through surface-entropy reduction.
Acta Crystallogr.,Sect.F, 70, 2014
4PO9
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BU of 4po9 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BR
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4POD
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BU of 4pod by Molmil
Structure of Triosephosphate Isomerase I170V mutant human enzyme.
分子名称: BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ...
著者Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P.
登録日2014-02-25
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
2X7R
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BU of 2x7r by Molmil
Crystal structure of a late fusion intermediate of HIV-1 gp41
分子名称: CHLORIDE ION, SODIUM ION, TRANSMEMBRANE PROTEIN GP41
著者Natrajan, G, Buzon, V, Weissenhorn, W.
登録日2010-03-03
公開日2010-05-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of HIV-1 Gp41 Including Both Fusion Peptide and Membrane Proximal External Regions.
Plos Pathog., 6, 2010
4PUV
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BU of 4puv by Molmil
URATE OXIDASE DI-AZIDE complex
分子名称: AZIDE ION, SODIUM ION, Uricase
著者Colloc'h, N, Prange, T.
登録日2014-03-14
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Azide inhibition of urate oxidase.
Acta Crystallogr.,Sect.F, 70, 2014
1B7R
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BU of 1b7r by Molmil
VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES
分子名称: PROTEIN (LYSOZYME), SODIUM ION
著者Takano, K, Ota, M, Ogasahara, K, Yamagata, Y, Nishikawa, K, Yutani, K.
登録日1999-01-25
公開日1999-02-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Experimental verification of the 'stability profile of mutant protein' (SPMP) data using mutant human lysozymes.
Protein Eng., 12, 1999
4PIU
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BU of 4piu by Molmil
CRYSTAL STRUCTURE OF BANANA LECTIN H84T MUTANT
分子名称: GLYCEROL, Ripening-associated protein, SODIUM ION
著者Meagher, J.L, Stuckey, J.A.
登録日2014-05-09
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity.
Cell, 163, 2015
4PJ8
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BU of 4pj8 by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT TRBV20 TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-05-12
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
3GED
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BU of 3ged by Molmil
Fingerprint and Structural Analysis of a Apo SCOR enzyme from Clostridium thermocellum
分子名称: GLYCEROL, SODIUM ION, Short-chain dehydrogenase/reductase SDR, ...
著者Huether, R, Liu, Z.J, Xu, H, Wang, B.C, Pletnev, V, Mao, Q, Umland, T, Duax, W.
登録日2009-02-25
公開日2009-03-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Sequence fingerprint and structural analysis of the SCOR enzyme A3DFK9 from Clostridium thermocellum.
Proteins, 78, 2010
4TTT
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BU of 4ttt by Molmil
Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form - oxidized state 3
分子名称: CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ...
著者Schmidt, A, Kalms, J, Scheerer, P.
登録日2014-06-23
公開日2015-01-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Tracking the route of molecular oxygen in O2-tolerant membrane-bound [NiFe] hydrogenase
Proc.Natl.Acad.Sci.Usa, 2018
4TR8
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BU of 4tr8 by Molmil
Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa
分子名称: DNA polymerase III subunit beta, SODIUM ION
著者Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
登録日2014-06-15
公開日2014-09-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
3FVU
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BU of 3fvu by Molmil
Crystal Structure of Human Kynurenine Aminotransferase I in Complex with Indole-3-acetic Acid
分子名称: 1H-INDOL-3-YLACETIC ACID, GLYCEROL, Kynurenine--oxoglutarate transaminase 1, ...
著者Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J.
登録日2009-01-16
公開日2009-05-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K
J.Med.Chem., 52, 2009
2WD0
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BU of 2wd0 by Molmil
CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2
分子名称: CADHERIN-23, CALCIUM ION, CHLORIDE ION, ...
著者Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P.
登録日2009-03-18
公開日2010-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
3G3K
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BU of 3g3k by Molmil
Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K E757Q mutant with glutamate and NaCl at 1.24 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
著者Chaudhry, C, Mayer, M.L.
登録日2009-02-02
公開日2009-06-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
1B5X
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BU of 1b5x by Molmil
Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and x-ray analysis of six ser->ala mutants
分子名称: PROTEIN (LYSOZYME), SODIUM ION
著者Takano, K, Yamagata, Y, Kubota, M, Funahashi, J, Fujii, S, Yutani, K.
登録日1999-01-11
公開日1999-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six Ser --> Ala mutants.
Biochemistry, 38, 1999
2VWM
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BU of 2vwm by Molmil
Aminopyrrolidine Factor Xa inhibitor
分子名称: (4R)-4-{[(5-chlorothiophen-2-yl)carbonyl]amino}-N-(cyclopropylmethyl)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-L-prolinamide, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN, ...
著者Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W.
登録日2008-06-26
公開日2009-07-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
Eur.J.Med.Chem., 44, 2009

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