5I01
 
 | | Structure of phosphoheptose isomerase GmhA from Neisseria gonorrhoeae | | 分子名称: | Phosphoheptose isomerase, ZINC ION | | 著者 | Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V. | | 登録日 | 2016-02-03 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Functional and structural studies on the Neisseria gonorrhoeae GmhA, the first enzyme in the glycero-manno-heptose biosynthesis pathways, demonstrate a critical role in lipooligosaccharide synthesis and gonococcal viability.
Microbiologyopen, 6, 2017
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1AVT
 | | SUBTILISIN CARLSBERG D-PARA-CHLOROPHENYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | | 分子名称: | SODIUM ION, SUBTILISIN CARLSBERG, TYPE VIII | | 著者 | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | | 登録日 | 1997-09-19 | | 公開日 | 1998-03-25 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
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3VP0
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3VP2
 | | Crystal structure of human glutaminase in complex with inhibitor 2 | | 分子名称: | 5,5'-(sulfanediyldiethane-2,1-diyl)bis(1,3,4-thiadiazol-2-amine), Glutaminase kidney isoform, mitochondrial, ... | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6S6T
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3VT1
 | | Crystal structure of Ct1,3Gal43A in complex with galactose | | 分子名称: | Ricin B lectin, beta-D-galactopyranose | | 著者 | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | | 登録日 | 2012-05-18 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.187 Å) | | 主引用文献 | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum
J.Struct.Biol., 180, 2012
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3VOZ
 | | Crystal structure of human glutaminase in complex with BPTES | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide), ... | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7RU6
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3VOY
 | | Crystal structure of human glutaminase in apo form | | 分子名称: | Glutaminase kidney isoform, mitochondrial, SULFATE ION | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7RUG
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4NZF
 | | Crystal structure of Abp-D197A (a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus), in complex with arabinose | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-12 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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4NX0
 | | Crystal structure of Abp-WT, a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-08 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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4NXK
 | | Crystal structure of Abp-D197A, a catalytic mutant of a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-09 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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6S6S
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6S6X
 | | Structure of Azospirillum brasilense Glutamate Synthase in a6b6 oligomeric state. | | 分子名称: | FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Chaves-Sanjuan, A, Camilloni, C, Bolognesi, M. | | 登録日 | 2019-07-03 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM Structures of Azospirillum brasilense Glutamate Synthase in Its Oligomeric Assemblies.
J.Mol.Biol., 431, 2019
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8XBE
 | | Human GPR34 -Gi complex bound to S3E-LysoPS | | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[(~{Z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34.
Nat Commun, 15, 2024
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8XBG
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8XBI
 | | Human GPR34 -Gi complex bound to M1, receptor focused | | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Probable G-protein coupled receptor 34 | | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-06 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34.
Nat Commun, 15, 2024
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8XBH
 | | Human GPR34 -Gi complex bound to M1 | | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-06 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34.
Nat Commun, 15, 2024
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7D2L
 | | Crystal structure of the Cas12i1 R-loop complex before target DNA cleavage | | 分子名称: | 12i1-D647A, CITRIC ACID, DNA (26-MER), ... | | 著者 | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | 登録日 | 2020-09-16 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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7D8C
 | | Crystal structure of the Cas12i1-crRNA binary complex | | 分子名称: | 12i1, CITRIC ACID, RNA (3-MER), ... | | 著者 | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | 登録日 | 2020-10-07 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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7D3J
 | | Crystal structure of the Cas12i1 R-loop complex after target DNA cleavage | | 分子名称: | 12i1-WT, CITRIC ACID, DNA (23-MER), ... | | 著者 | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | 登録日 | 2020-09-19 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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7DJI
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8QEF
 | | A carbohydrate esterase family 15 (CE15) glucuronoyl esterase from Phocaeicola ATCC 8482 bound to novel ligand. | | 分子名称: | 1,2-ETHANEDIOL, Putative acetyl xylan esterase, beta-D-galactopyranuronic acid | | 著者 | Banerjee, S, Poulsen, J.N, Mazurkewich, S, Seveso, A, Larsbrink, J, Lo Leggio, L. | | 登録日 | 2023-08-31 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds.
Appl.Environ.Microbiol., 90, 2024
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8QCL
 | | A carbohydrate esterase family 15 (CE15) glucuronoyl esterase from Phocaeicola vulgatus ATCC 8482 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Banerjee, S, Poulsen, J.N, Mazurkewich, S, Seveso, A, Larsbrink, J, Lo Leggio, L. | | 登録日 | 2023-08-27 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds.
Appl.Environ.Microbiol., 90, 2024
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