PDB: 13488 件ウェブページステータス検索Chemie searchBIRD

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7PC8	The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC7	The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC9	The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: CALCIUM ION, Protein Tax-1, Synaptojanin-2-binding protein,Annexin A2 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC3	The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: CALCIUM ION, Disks large homolog 1,Annexin A2, GLYCEROL, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
6MZC	Human TFIID BC core 分子名称: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
7QQN	The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2022-01-10 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7QQM	The PDZ domain of LRRC7 fused with ANXA2 分子名称: CALCIUM ION, GLYCEROL, Leucine-rich repeat-containing protein 7,Annexin A2 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2022-01-10 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
5LQ0	Crystal structure of Tyr24 phosphorylated Annexin A2 at 2.9 A resolution 分子名称: Annexin A2, CALCIUM ION 著者 Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. 登録日 2016-08-15 公開日 2017-07-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. Structure, 25, 2017
6YOV	OCT4-SOX2-bound nucleosome - SHL+6 分子名称: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... 著者 Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. 登録日 2020-04-15 公開日 2020-05-06 最終更新日 2020-07-08 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
7OH9	Nucleosome with TBP and TFIIA bound at SHL -6 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Wang, H, Cramer, P. 登録日 2021-05-09 公開日 2021-07-28 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
5N7G	MAGI-1 complexed with a synthetic pRSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
9ATK	BIFUNCTIONAL INHIBITION OF NEUTROPHIL ELASTASE AND CATHEPSIN G by Eap4 of S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin-G, ... 著者 Mishra, N.B, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2024-02-27 公開日 2024-06-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Bifunctional Inhibition of Neutrophil Elastase and Cathepsin-G by Eap4 from S. aureus To Be Published
8ZWH	Heparin bound E46K alpha-synuclein fibril 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Liu, C, Li, D. 登録日 2024-06-13 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Heparin bound E46K alpha-synuclein fibril To Be Published
8ZWI	Chondroitin sulfate bound alpha-synuclein fibril 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Liu, C, Li, D. 登録日 2024-06-13 公開日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Chondroitin sulfate bound alpha-synuclein fibril To Be Published
9IJP	Polyphosphate bound alpha-synuclein fibril 分子名称: Alpha-synuclein, Tetraphosphate 著者 Tao, Y.Q, Liu, C, Li, D. 登録日 2024-06-25 公開日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Polyphosphate bound alpha-synuclein fibril To Be Published
4WUL	Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 26bp DNA 分子名称: DNA (26-MER), Response regulator receiver domain protein 著者 Davlieva, M, Shamoo, Y. 登録日 2014-11-02 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin. Nucleic Acids Res., 43, 2015
9BAQ	CryoEM structure of DIM2-HP1-H3K9me3-DNA complex 分子名称: DNA (5'-D(*AP*CP*TP*AP*CP*T)-R(P*(PYO))-D(P*CP*TP*CP*CP*TP*CP*CP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*TP*AP*GP*T)-3'), DNA (cytosine-5-)-methyltransferase, ... 著者 Song, J, Shao, Z. 登録日 2024-04-04 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 CryoEM structure of DIM2-HP1-H3K9me3-DNA complex To Be Published
9CK3	Cryo-EM structure of in-vitro alpha-synuclein fibril 分子名称: Alpha-synuclein 著者 Sanchez, J.C, Borcik, C.G, Tonelli, M, Sibert, B, Rienstra, C.M, Wright, E.R. 登録日 2024-07-08 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.04 Å) 主引用文献 Multimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils To Be Published
9EUU	Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo 分子名称: Alpha-synuclein 著者 Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F. 登録日 2024-03-28 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (1.93 Å) 主引用文献 Multiple System Atrophy: Insights from aSyn Fibril Structure To Be Published
3T0M	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: (2-{2-[(2,5-dimethoxyphenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Thiel, P, Ottmann, C. 登録日 2011-07-20 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3SQQ	CDK2 in complex with inhibitor RC-3-96 分子名称: 1,2-ETHANEDIOL, 4-{[4-amino-5-(2-methylbenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-07-06 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
4DHP	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3SW4	Crystal Structure of the CDK2 in complex with thiazolylpyrimidine inhibitor 分子名称: ACETATE ION, Cyclin-dependent kinase 2, N'-[4-(2-amino-4-methyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N,N-dimethylbenzene-1,4-diamine 著者 Kang, Y.N, Stuckey, J.A. 登録日 2011-07-13 公開日 2012-08-01 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the CDK2 in complex with a thiazolylpyrimidine inhibitor To be Published
4WU4	Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 22bp DNA 分子名称: DNA (5'-D(P*AP*AP*AP*TP*CP*GP*TP*TP*CP*TP*TP*AP*AP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*TP*AP*AP*GP*AP*AP*CP*GP*AP*TP*TP*T)-3'), GLYCEROL, ... 著者 Davlieva, M, Shamoo, Y. 登録日 2014-10-31 公開日 2015-05-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin. Nucleic Acids Res., 43, 2015
4WVP	Crystal structure of an activity-based probe HNE complex 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BTN-3V3-NLB-OMT-OIC-3V2, ... 著者 Lechtenberg, B.C, Kasperkiewicz, P, Robinson, H.R, Drag, M, Riedl, S.J. 登録日 2014-11-06 公開日 2015-02-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 The Elastase-PK101 Structure: Mechanism of an Ultrasensitive Activity-based Probe Revealed. Acs Chem.Biol., 10, 2015

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