8IUH
 
 | | RNA polymerase III pre-initiation complex open complex 1 | | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | | 登録日 | 2023-03-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
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2E9R
 | | Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin | | 分子名称: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | | 著者 | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | | 登録日 | 2007-01-26 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
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1HHT
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2000-12-28 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HI0
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2000-12-31 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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2N3Q
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5IP9
 | | Structure of RNA Polymerase II-TFIIF complex | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | | 登録日 | 2016-03-09 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Transcription initiation complex structures elucidate DNA opening.
Nature, 533, 2016
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5IP7
 | | Structure of RNA Polymerase II-Tfg1 peptide complex | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | | 登録日 | 2016-03-09 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | Transcription initiation complex structures elucidate DNA opening.
Nature, 533, 2016
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8HYJ
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8ITY
 | | human RNA polymerase III pre-initiation complex closed DNA 1 | | 分子名称: | DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | | 登録日 | 2023-03-23 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
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6QCS
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6QCT
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8OKI
 | | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 | | 分子名称: | DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... | | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-24 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
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9ER2
 | | PolII-TCR-STK19 structure. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ... | | 著者 | Kokic, G. | | 登録日 | 2024-03-22 | | 公開日 | 2024-12-04 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair.
Cell, 187, 2024
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7FJI
 | | human Pol III elongation complex | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Hou, H, Xu, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
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7FJJ
 | | human Pol III pre-termination complex | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Hou, H, Xu, Y. | | 登録日 | 2021-08-04 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
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5M3J
 | | Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | | 分子名称: | DNA-directed RNA polymerase subunit, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Lukarska, M, Pflug, A, Cusack, S. | | 登録日 | 2016-10-14 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
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5M3H
 | | Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | | 分子名称: | PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Lukarska, M, Pflug, A, Cusack, S. | | 登録日 | 2016-10-14 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
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2WCX
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8CRO
 | | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex | | 分子名称: | DNA Non-Template Strand, DNA Template Strand, DNA-directed RNA polymerase subunit Rpo10, ... | | 著者 | Tarau, D.M, Grunberger, F, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | | 登録日 | 2023-03-08 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
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4WYL
 | | Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus | | 分子名称: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. | | 登録日 | 2014-11-17 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
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1DZF
 | | RPB5 from S.cerevisiae | | 分子名称: | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 | | 著者 | Todone, F, Weinzierl, R.O.J, Brick, P, Onesti, S. | | 登録日 | 2000-02-25 | | 公開日 | 2000-06-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Transcription Factor Interaction Target
Proc.Natl.Acad.Sci.USA, 97, 2000
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8HKC
 | | Cryo-EM structure of E. coli RNAP sigma32 complex | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Wu, S, Ma, L.X. | | 登録日 | 2022-11-25 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | | 主引用文献 | Structural Insight into the Mechanism of sigma 32-Mediated Transcription Initiation of Bacterial RNA Polymerase.
Biomolecules, 13, 2023
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8AC2
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4Y3C
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7SZK
 | | Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex | | 分子名称: | (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Shin, Y, Murakami, K.S. | | 登録日 | 2021-11-28 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis.
Acs Infect Dis., 8, 2022
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