PDB: 1446 件ウェブページステータス検索Chemie searchBIRD

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7RIM	RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 分子名称: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
7RIP	RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP 分子名称: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
7RIW	RNA polymerase II elongation complex scaffold 2, without polyamide 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
7RIX	RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 分子名称: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
3QT1	RNA polymerase II variant containing A Chimeric RPB9-C11 subunit 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. 登録日 2011-02-22 公開日 2011-03-23 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Evolution of two modes of intrinsic RNA polymerase transcript cleavage. J.Biol.Chem., 286, 2011
5X51	RNA Polymerase II from Komagataella Pastoris (Type-3 crystal) 分子名称: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... 著者 Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. 登録日 2017-02-14 公開日 2017-05-17 実験手法 X-RAY DIFFRACTION (6.996 Å) 主引用文献 Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
5X50	RNA Polymerase II from Komagataella Pastoris (Type-2 crystal) 分子名称: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... 著者 Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. 登録日 2017-02-14 公開日 2017-05-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.293 Å) 主引用文献 Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
5X4Z	RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) 分子名称: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... 著者 Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. 登録日 2017-02-14 公開日 2017-05-17 実験手法 X-RAY DIFFRACTION (7.8 Å) 主引用文献 Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
4YM7	RNA polymerase I structure with an alternative dimer hinge 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P. 登録日 2015-03-06 公開日 2015-09-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallogr.,Sect.D, 71, 2015
5M64	RNA Polymerase I elongation complex with A49 tandem winged helix domain 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. 登録日 2016-10-24 公開日 2016-12-21 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
5M5W	RNA Polymerase I open complex 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. 登録日 2016-10-23 公開日 2016-12-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
5M5Y	RNA Polymerase I elongation complex 2 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. 登録日 2016-10-23 公開日 2016-12-21 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
5M5X	RNA Polymerase I elongation complex 1 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. 登録日 2016-10-23 公開日 2016-12-21 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
6RQH	RNA Polymerase I Closed Conformation 1 (CC1) 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-15 公開日 2019-12-11 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
3K1F	Crystal structure of RNA Polymerase II in complex with TFIIB 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P. 登録日 2009-09-27 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 RNA polymerase II-TFIIB structure and mechanism of transcription initiation. Nature, 462, 2009
6RRD	RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-17 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RUO	RNA Polymerase I Open Complex conformation 1 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-28 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RQT	RNA Polymerase I-tWH-Rrn3-DNA 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-16 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RUI	RNA Polymerase I Pre-initiation complex DNA opening intermediate 2 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-28 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RQL	RNA Polymerase I Closed Conformation 2 (CC2) 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-05-16 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
6RWE	RNA Polymerase I Open Complex conformation 2 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Mueller, C.W, Sadian, Y, Tafur, L. 登録日 2019-06-04 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
8JH2	RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome 分子名称: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... 著者 Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2023-05-22 公開日 2023-11-29 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
8JH4	RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2023-05-22 公開日 2023-11-29 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
8JH3	RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2023-05-22 公開日 2023-11-29 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
4C2M	Structure of RNA polymerase I at 2.8 A resolution 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Engel, C, Sainsbury, S, Cheung, A.C, Kostrewa, D, Cramer, P. 登録日 2013-08-19 公開日 2013-10-23 最終更新日 2015-08-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RNA Polymerase I Structure and Transcription Regulation. Nature, 502, 2013

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