PDB: 200 件ウェブページステータス検索Chemie searchBIRD

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6TTE	Beta-galactosidase in complex with PETG 分子名称: 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-27 公開日 2020-01-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
6SD0	Structure of beta-galactosidase from Thermotoga maritima. 分子名称: Beta-galactosidase, MAGNESIUM ION 著者 Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J. 登録日 2019-07-26 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering. Acs Chem.Biol., 15, 2020
6TSH	Beta-galactosidase in complex with deoxygalacto-nojirimycin 分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-20 公開日 2020-01-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
6TSK	Beta-galactosidase in complex with L-ribose 分子名称: Beta-galactosidase, MAGNESIUM ION, beta-L-ribopyranose 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-20 公開日 2020-01-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
6NZG	Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine 分子名称: (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, Beta-galactosidase, CALCIUM ION, ... 著者 Pellock, S.J, Jariwala, P.B, Redinbo, M.R. 登録日 2019-02-13 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. Acs Chem.Biol., 15, 2020
6U7I	Faecalibacterium prausnitzii Beta-glucuronidase 分子名称: Beta-glucuronidase 著者 Ervin, S.M, Redinbo, M.R. 登録日 2019-09-03 公開日 2019-10-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Gut microbial beta-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens. J.Biol.Chem., 294, 2019
6U7J	Uncultured Clostridium sp. Beta-glucuronidase 分子名称: Beta-glucuronidase, CALCIUM ION 著者 Ervin, S.M, Redinbo, M.R. 登録日 2019-09-03 公開日 2019-10-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Gut microbial beta-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens. J.Biol.Chem., 294, 2019
6HPD	The structure of a beta-glucuronidase from glycoside hydrolase family 2 分子名称: BROMIDE ION, Beta-galactosidase (GH2), MAGNESIUM ION 著者 Robb, C.S, Gerlach, N, Reisky, L, Bornshoeru, U, Hehemann, J.H. 登録日 2018-09-20 公開日 2019-07-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan. Nat.Chem.Biol., 15, 2019
6D7J	The Crystal Structure of Parabacteroides merdae Beta-Glucuronidase (GUS) with Glycerol in Active-Site 分子名称: Beta-Glucuronidase, GLYCEROL, POTASSIUM ION, ... 著者 Little, M.S, Redinbo, M.R. 登録日 2018-04-24 公開日 2019-05-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Active site flexibility revealed in crystal structures of Parabacteroides merdae beta-glucuronidase from the human gut microbiome. Protein Sci., 27, 2018
6CXS	Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine 分子名称: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein 著者 Wallace, B.D, Redinbo, M.R. 登録日 2018-04-04 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy. Proc.Natl.Acad.Sci.USA, 2020
6NCY	Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans 分子名称: Beta-glucuronidase, GLYCEROL, NICKEL (II) ION, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-12-12 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
6NCZ	Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans bound to phenyl-thio-beta-D-glucuronide 分子名称: Beta-glucuronidase, GLYCEROL, phenyl 1-thio-beta-D-glucopyranosiduronic acid 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-12-12 公開日 2019-02-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
6EC6	Ruminococcus gnavus Beta-glucuronidase 分子名称: Beta-glucuronidase, CHLORIDE ION, GLYCEROL 著者 Biernat, K.A, Redinbo, M.R. 登録日 2018-08-07 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6ED2	Faecalibacterium prausnitzii beta-glucuronidase 分子名称: FORMIC ACID, GLYCEROL, Glycosyl hydrolase family 2, ... 著者 Pellock, S.J, Biernat, K.A, Redinbo, M.R. 登録日 2018-08-08 公開日 2019-02-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6ECA	Lactobacillus rhamnosus Beta-glucuronidase 分子名称: Beta-glucuronidase, CHLORIDE ION, GLYCEROL 著者 Biernat, K.A, Pellock, S.J, Bhatt, A.P, Bivins, M.M, Walton, W.G, Tran, B.N.T, Wei, L, Snider, M.C, Cesmat, A.P, Tripathy, A, Erie, D.A, Redinbo, M.R.R. 登録日 2018-08-07 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.853 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6ED1	Bacteroides dorei Beta-glucuronidase 分子名称: Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION 著者 Biernat, K.A, Redinbo, M.R. 登録日 2018-08-08 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6MVF	Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 分子名称: Beta-galactosidase/beta-glucuronidase, FLAVIN MONONUCLEOTIDE 著者 Pellock, S.J, Redinbo, M.R. 登録日 2018-10-25 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome. J. Mol. Biol., 431, 2019
5Z19	The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine 分子名称: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Beta-glucuronidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
5Z1A	The crystal structure of Bacteroides fragilis beta-glucuronidase in complex with uronic isofagomine 分子名称: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Putative beta-galactosidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
5Z18	The crystal structure of Ruminococcus gnavus beta-glucuronidase 分子名称: Beta-glucuronidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
5Z1B	Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide 分子名称: 3-HYDROXY-2H-CHROMEN-2-ONE, Glycosyl hydrolase family 2, TIM barrel domain protein, ... 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
6D6W	Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate 分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-23 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
6D8G	D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 分子名称: Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-26 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
6D1N	Apo structure of Bacteroides uniformis Beta-glucuronidase 1 分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-12 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
6D41	Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone 分子名称: (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-17 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018

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