5C71
 
 | | The structure of Aspergillus oryzae a-glucuronidase complexed with glycyrrhetinic acid monoglucuronide | | 分子名称: | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, Glucuronidase, alpha-D-glucopyranuronic acid | | 著者 | Sun, H.L, Lv, B, Huang, S, Li, C, Jiang, T. | | 登録日 | 2015-06-24 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure-guided engineering of the substrate specificity of a fungal beta-glucuronidase toward triterpenoid saponins.
J.Biol.Chem., 293, 2018
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5A1A
 | | 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor | | 分子名称: | 2-phenylethyl 1-thio-beta-D-galactopyranoside, BETA-GALACTOSIDASE, MAGNESIUM ION, ... | | 著者 | Bartesaghi, A, Merk, A, Banerjee, S, Matthies, D, Wu, X, Milne, J, Subramaniam, S. | | 登録日 | 2015-04-29 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | 2.2 A Resolution Cryo-Em Structure of Beta-Galactosidase in Complex with a Cell-Permeant Inhibitor
Science, 348, 2015
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8Q51
 | | Beta-galactosidase from Bacillus circulans conformational state 2 | | 分子名称: | beta-galactosidase | | 著者 | Kascakova, B, Hovorkova, M, Petraskova, L, Novacek, J, Pinkas, D, Gardian, Z, Kren, V, Bojarova, P, Kuta Smatanova, I. | | 登録日 | 2023-08-07 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | The variable structural flexibility of the Bacillus circulans beta-galactosidase isoforms determines their unique functionalities.
Structure, 2024
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8Q2H
 | | beta-galactosidase from Bacillus circulans | | 分子名称: | beta-galactosidase | | 著者 | Kascakova, B, Hovorkova, M, Petraskova, L, Novacek, J, Pinkas, D, Gardian, Z, Kren, V, Bojarova, P, Kuta Smatanova, I. | | 登録日 | 2023-08-02 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The variable structural flexibility of the Bacillus circulans beta-galactosidase isoforms determines their unique functionalities.
Structure, 2024
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8Q4Y
 | | Beta-galactosidase from Bacillus circulans conformational state 1 | | 分子名称: | beta-galactosidase | | 著者 | Kascakova, B, Hovorkova, M, Petraskova, L, Novacek, J, Pinkas, D, Gardian, Z, Kren, V, Bojarova, P, Kuta Smatanova, I. | | 登録日 | 2023-08-07 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | The variable structural flexibility of the Bacillus circulans beta-galactosidase isoforms determines their unique functionalities.
Structure, 2024
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4JKK
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5Z19
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5Z1A
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4JKM
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4JHZ
 | | Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide | | 分子名称: | 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide, Beta-glucuronidase | | 著者 | Roberts, A.B, Wallace, B.D, Redinbo, M.R. | | 登録日 | 2013-03-05 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.831 Å) | | 主引用文献 | Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity.
Mol.Pharmacol., 84, 2013
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4JKL
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5Z18
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5Z1B
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5CZK
 | | Structure of E. coli beta-glucuronidase bound with a novel, potent inhibitor 1-((6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea | | 分子名称: | 1-[(6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea, Beta-glucuronidase | | 著者 | Roberts, A.R, Wallace, B.R, Redinbo, M.R. | | 登録日 | 2015-07-31 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
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6QUB
 | | Truncated beta-galactosidase III from Bifidobacterium bifidum in complex with galactose | | 分子名称: | Beta-galactosidase, CALCIUM ION, beta-D-galactopyranose | | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | | 登録日 | 2019-02-27 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
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6QUC
 | | Truncated beta-galactosidase III from Bifidobacterium bifidum | | 分子名称: | Beta-galactosidase, CALCIUM ION, IMIDAZOLE | | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | | 登録日 | 2019-02-27 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
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6TTE
 | | Beta-galactosidase in complex with PETG | | 分子名称: | 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION | | 著者 | Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. | | 登録日 | 2019-12-27 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
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6QUD
 | | 2-deoxy-galactose reaction intermediate of a Truncated beta-galactosidase III from Bifidobacterium bifidum | | 分子名称: | 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, CALCIUM ION | | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | | 登録日 | 2019-02-27 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum
To Be Published
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6TSH
 | | Beta-galactosidase in complex with deoxygalacto-nojirimycin | | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION | | 著者 | Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. | | 登録日 | 2019-12-20 | | 公開日 | 2020-01-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
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6U7J
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6S6Z
 | | Structure of beta-Galactosidase from Thermotoga maritima | | 分子名称: | Beta-galactosidase, MAGNESIUM ION | | 著者 | Miguez-Amil, S, Jimenez-Ortega, E, Ramirez Escudero, M, Sanz-Aparicio, J, Fernandez-Leiro, R. | | 登録日 | 2019-07-04 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering.
Acs Chem.Biol., 15, 2020
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5T99
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5T9A
 | | Crystal structure of BuGH2Cwt | | 分子名称: | 1,2-ETHANEDIOL, Glycoside Hydrolase, SULFATE ION | | 著者 | Pluvinage, B, Boraston, A.B, Abbott, W.D. | | 登録日 | 2016-09-09 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
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6B6L
 | | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ... | | 著者 | Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2017-10-02 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838
To Be Published
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5T98
 | | Crystal structure of BuGH2Awt | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside Hydrolase | | 著者 | Pluvinage, B, Boraston, A.B. | | 登録日 | 2016-09-09 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
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