PDB: 200 件ウェブページステータス検索Chemie searchBIRD

---

5T9G	Crystal structure of BuGH2Cwt in complex with Galactoisofagomine 分子名称: 1,2-ETHANEDIOL, D-galacto-isofagomine, Glycoside Hydrolase 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-09-09 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
5T9A	Crystal structure of BuGH2Cwt 分子名称: 1,2-ETHANEDIOL, Glycoside Hydrolase, SULFATE ION 著者 Pluvinage, B, Boraston, A.B, Abbott, W.D. 登録日 2016-09-09 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
6MVF	Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 分子名称: Beta-galactosidase/beta-glucuronidase, FLAVIN MONONUCLEOTIDE 著者 Pellock, S.J, Redinbo, M.R. 登録日 2018-10-25 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome. J. Mol. Biol., 431, 2019
6NZG	Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine 分子名称: (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, Beta-galactosidase, CALCIUM ION, ... 著者 Pellock, S.J, Jariwala, P.B, Redinbo, M.R. 登録日 2019-02-13 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. Acs Chem.Biol., 15, 2020
5Z19	The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine 分子名称: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Beta-glucuronidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
5Z1A	The crystal structure of Bacteroides fragilis beta-glucuronidase in complex with uronic isofagomine 分子名称: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, Putative beta-galactosidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
6NCY	Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans 分子名称: Beta-glucuronidase, GLYCEROL, NICKEL (II) ION, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-12-12 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
4JKM	Crystal Structure of Clostridium perfringens beta-glucuronidase 分子名称: Beta-glucuronidase, Maltose-binding periplasmic protein 著者 Wallace, B.D, Redinbo, M.R. 登録日 2013-03-09 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.263 Å) 主引用文献 Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015
6NCZ	Crystal structure of hybrid beta-glucuronidase/beta-galacturonidase from Fusicatenibacter saccharivorans bound to phenyl-thio-beta-D-glucuronide 分子名称: Beta-glucuronidase, GLYCEROL, phenyl 1-thio-beta-D-glucopyranosiduronic acid 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-12-12 公開日 2019-02-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome. Biochemistry, 58, 2019
5Z18	The crystal structure of Ruminococcus gnavus beta-glucuronidase 分子名称: Beta-glucuronidase 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
5Z1B	Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide 分子名称: 3-HYDROXY-2H-CHROMEN-2-ONE, Glycosyl hydrolase family 2, TIM barrel domain protein, ... 著者 Dashnyam, P, Lin, H.Y, Lin, C.H. 登録日 2017-12-25 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity To Be Published
4JKK	Crystal Structure of Streptococcus agalactiae beta-glucuronidase in space group I222 分子名称: Beta-glucuronidase, MAGNESIUM ION 著者 Wallace, B.D, Redinbo, M.R. 登録日 2013-03-09 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015
4JHZ	Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide 分子名称: 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide, Beta-glucuronidase 著者 Roberts, A.B, Wallace, B.D, Redinbo, M.R. 登録日 2013-03-05 公開日 2013-08-28 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.831 Å) 主引用文献 Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity. Mol.Pharmacol., 84, 2013
4JKL	Crystal Structure of Streptococcus agalactiae beta-glucuronidase in space group P21212 分子名称: Beta-glucuronidase, MAGNESIUM ION 著者 Wallace, B.D, Redinbo, M.R. 登録日 2013-03-09 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.288 Å) 主引用文献 Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015
6D6W	Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate 分子名称: Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-23 公開日 2018-10-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
6D8G	D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 分子名称: Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION 著者 Walton, W.G, Pellock, S.J, Redinbo, M.R. 登録日 2018-04-26 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
5C70	The structure of Aspergillus oryzae beta-glucuronidase 分子名称: Glucuronidase 著者 Sun, H.L, Lv, B, Huang, S, Sun, Q.F, Li, C, Jiang, T. 登録日 2015-06-24 公開日 2016-06-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Enhancing the Thermostability of beta-Glucuronidase by Rationally Redesigning the Catalytic Domain Based on Sequence Alignment Strategy Ind Eng Chem Res, 55, 2016
5C71	The structure of Aspergillus oryzae a-glucuronidase complexed with glycyrrhetinic acid monoglucuronide 分子名称: (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, Glucuronidase, alpha-D-glucopyranuronic acid 著者 Sun, H.L, Lv, B, Huang, S, Li, C, Jiang, T. 登録日 2015-06-24 公開日 2016-06-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure-guided engineering of the substrate specificity of a fungal beta-glucuronidase toward triterpenoid saponins. J.Biol.Chem., 293, 2018
6ED2	Faecalibacterium prausnitzii beta-glucuronidase 分子名称: FORMIC ACID, GLYCEROL, Glycosyl hydrolase family 2, ... 著者 Pellock, S.J, Biernat, K.A, Redinbo, M.R. 登録日 2018-08-08 公開日 2019-02-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6ECA	Lactobacillus rhamnosus Beta-glucuronidase 分子名称: Beta-glucuronidase, CHLORIDE ION, GLYCEROL 著者 Biernat, K.A, Pellock, S.J, Bhatt, A.P, Bivins, M.M, Walton, W.G, Tran, B.N.T, Wei, L, Snider, M.C, Cesmat, A.P, Tripathy, A, Erie, D.A, Redinbo, M.R.R. 登録日 2018-08-07 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.853 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6ED1	Bacteroides dorei Beta-glucuronidase 分子名称: Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION 著者 Biernat, K.A, Redinbo, M.R. 登録日 2018-08-08 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
6TTE	Beta-galactosidase in complex with PETG 分子名称: 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-27 公開日 2020-01-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
5CZK	Structure of E. coli beta-glucuronidase bound with a novel, potent inhibitor 1-((6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea 分子名称: 1-[(6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea, Beta-glucuronidase 著者 Roberts, A.R, Wallace, B.R, Redinbo, M.R. 登録日 2015-07-31 公開日 2015-10-14 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015
6SD0	Structure of beta-galactosidase from Thermotoga maritima. 分子名称: Beta-galactosidase, MAGNESIUM ION 著者 Jimenez-Ortega, E, Ramirez-Escudero, M, Sanz-Aparicio, J. 登録日 2019-07-26 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering. Acs Chem.Biol., 15, 2020
6TSH	Beta-galactosidase in complex with deoxygalacto-nojirimycin 分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-20 公開日 2020-01-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020

<12345678>