PDB: 250 件ウェブページステータス検索Chemie searchBIRD

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8TUF	Crystal structure of human norovirus RNA-dependent RNA-polymerase 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, RNA-dependent RNA-polymerase 著者 Prasad, B.V.V, Kaundal, S, Sankaran, B. 登録日 2023-08-16 公開日 2024-12-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal structure of human norovirus RNA-dependent RNA-polymerase To Be Published
9JKD	Crystal structure of Aspergillus fumigatus polymycovirus 1 ploymerase elongation complex 分子名称: GLYCEROL, RNA (30-MER), RNA (5'-R(P*GP*GP*AP*UP*AP*UP*AP*AP*U)-3'), ... 著者 Jia, H, Gong, P. 登録日 2024-09-15 公開日 2025-03-26 最終更新日 2025-04-30 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element. Sci Adv, 11, 2025
9JKC	Crystal structure of Aspergillus fumigatus polymycovirus 1 ploymerase (residues 85-763) in its apo state 分子名称: RNA dependent RNA polymerase 著者 Jia, H, Cao, S, Gong, P. 登録日 2024-09-15 公開日 2025-03-26 最終更新日 2025-04-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element. Sci Adv, 11, 2025
6LSF	Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form) 分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... 著者 Wang, M, Shu, B, Jing, X, Gong, P. 登録日 2020-01-17 公開日 2020-04-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
2D7S	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein 分子名称: RNA-dependent RNA polymerase, VPg1 protein 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-11-29 公開日 2006-03-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
2EC0	RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-02-09 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
7W9S	Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form) 分子名称: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... 著者 Wang, M, Gong, P. 登録日 2021-12-10 公開日 2022-11-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis. Nucleic Acids Res., 50, 2022
1HHS	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2000-12-28 公開日 2001-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
1HHT	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template 分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2000-12-28 公開日 2001-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
1HI1	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2001-01-01 公開日 2001-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
6LSH	Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form) 分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... 著者 Li, R, Wang, M, Jing, X, Gong, P. 登録日 2020-01-17 公開日 2020-04-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.231 Å) 主引用文献 Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
6LSG	Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form) 分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... 著者 Li, R, Wang, M, Jing, X, Gong, P. 登録日 2020-01-17 公開日 2020-04-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
2F8E	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein 分子名称: MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-12-02 公開日 2006-03-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
1HI0	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex 分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2000-12-31 公開日 2001-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
1HI8	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 分子名称: MAGNESIUM ION, P2 PROTEIN 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2001-01-03 公開日 2001-03-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
2E9Z	Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP 分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-01-29 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
1KHV	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ 分子名称: LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE 著者 Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. 登録日 2001-12-01 公開日 2002-01-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
2E9T	Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-01-26 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9R	Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin 分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-01-26 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
3OL9	Poliovirus polymerase elongation complex with 3'-deoxy-CTP 分子名称: ISOPROPYL ALCOHOL, PYROPHOSPHATE 2-, Polymerase, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL7	Poliovirus polymerase elongation complex with CTP 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL8	Poliovirus polymerase elongation complex with CTP-Mn 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OL6	Poliovirus polymerase elongation complex 分子名称: ISOPROPYL ALCOHOL, Polymerase, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*CP*GP*GP*AP*AP*A)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3OLA	Poliovirus polymerase elongation complex with 2'-deoxy-CTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
2JLF	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-08 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008

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