PDB: 266 件ウェブページステータス検索Chemie searchBIRD

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4B9V	Structure of the high fidelity DNA polymerase I with extending from an oxidative formamidopyrimidine-dG DNA lesion -dA basepair. 分子名称: 5'-D(*CP*AP*TP*FOXP*AP*GP*AP*GP*TP*CP*AP*GP*GP*CP*TP)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*TP*AP*AP)-3', DNA POLYMERASE, ... 著者 Gehrke, T.H, Lischke, U, Arnold, S, Schneider, S, Carell, T. 登録日 2012-09-06 公開日 2013-04-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Unexpected Non-Hoogsteen-Based Mutagenicity Mechanism of Fapy-DNA Lesions. Nat.Chem.Biol., 9, 2013
4B9S	Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion outside of the pre-insertion site. 分子名称: 5'-D(*AP*CP*CP*TP*GP*AP*CP*TP*CP*TP)-3', 5'-D(*CP*AP*TP*FOXP*AP*GP*AP*GP*TP*CP*AP*GP*GP*TP*TP)-3', DNA POLYMERASE, ... 著者 Gehrke, T.H, Lischke, U, Arnold, S, Schneider, S, Carell, T. 登録日 2012-09-06 公開日 2013-04-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Unexpected Non-Hoogsteen-Based Mutagenicity Mechanism of Fapy-DNA Lesions. Nat.Chem.Biol., 9, 2013
4BDP	CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 11 BASE PAIRS OF DUPLEX DNA AFTER ADDITION OF TWO DATP RESIDUES 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*AP*TP*GP*CP*AP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*GP*CP*AP*TP*GP*AP*TP*GP*C)-3'), MAGNESIUM ION, ... 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1997-11-17 公開日 1999-01-13 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
4XVM	Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain rotated out 分子名称: DNA (5'-D(*CP*TP*AP*GP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*G)-3'), DNA polymerase nu 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XVI	Binary complex of human polymerase nu and DNA with the finger domain ajar 分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XIU	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant with DNA containing TTT overhang 分子名称: DNA polymerase I, thermostable, MAGNESIUM ION, ... 著者 Wu, E.Y. 登録日 2015-01-07 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
4XVK	Binary complex of human polymerase nu and DNA with the finger domain closed 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XVL	Binary complex of human polymerase nu and DNA with the finger domain open 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... 著者 Lee, Y.-S, Yang, W. 登録日 2015-01-27 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4YFU	Crystal structure of open Bacillus fragment DNA polymerase bound to DNA and dTTP 分子名称: DNA polymerase, Primer DNA, SULFATE ION, ... 著者 Wu, E.Y. 登録日 2015-02-25 公開日 2015-07-22 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Closing Mechanism of DNA Polymerase I at Atomic Resolution. Structure, 23, 2015
1QSS	DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ... 著者 Li, Y, Mitaxov, V, Waksman, G. 登録日 1999-06-23 公開日 1999-08-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
2XY7	Crystal structure of a salicylic aldehyde base in the pre-insertion site of fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*GP)-3', 5'-D(*SAYP*CP*GP*AP*GP*TP*CP*AP*GP*GP*CP)-3', DNA POLYMERASE I, ... 著者 Kaul, C, Mueller, M, Wagner, M, Schneider, S, Carell, T. 登録日 2010-11-15 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Reversible Bond Formation Enables the Replication and Amplification of a Crosslinking Salen Complex as an Orthogonal Base Pair. Nature Chem., 3, 2011
3KTQ	CRYSTAL STRUCTURE OF AN ACTIVE TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'), ... 著者 Li, Y, Waksman, G. 登録日 1998-07-28 公開日 1999-01-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J., 17, 1998
2XY6	Crystal structure of a salicylic aldehyde basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*GP*GP*GP*AP*SAYP*GP*GP*TP*CP)-3', ... 著者 Kaul, C, Mueller, M, Wagner, M, Schneider, S, Carell, T. 登録日 2010-11-15 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Reversible Bond Formation Enables the Replication and Amplification of a Crosslinking Salen Complex as an Orthogonal Base Pair. Nature Chem., 3, 2011
2Y1J	CRYSTAL STRUCTURE OF A R-DIASTEREOMER ANALOGUE OF THE SPORE PHOTOPRODUCT IN COMPLEX WITH FRAGMENT DNA POLYMERASE I FROM BACILLUS STEAROTHERMOPHILUS 分子名称: 5'-D(*AP*GP*GP*GP*QBTP*THM*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*AP*CP*CP*CP*TP)-3', DNA POLYMERASE I, ... 著者 Heil, K, Schneider, S, Mueller, M, Kneuttinger, A.C, Carell, T. 登録日 2010-12-08 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the Uv-Induced Spore Photoproduct DNA Lesion. Chemistry, 17, 2011
1QTM	DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS 分子名称: 5'-D(*AP*AP*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3', DNA POLYMERASE I, ... 著者 Li, Y, Mitaxov, V, Waksman, G. 登録日 1999-06-28 公開日 1999-08-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
2XO7	Crystal structure of a dA:O-allylhydroxylamine-dC basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: 5'-D(*AP*GP*GP*AP*AP*TP*GP*GP*TP*CP*A)-3', 5'-D(*GP*AP*CP*CP*AP*TP*47C*CP*CP*T)-3', DNA POLYMERASE I, ... 著者 Muenzel, M, Lercher, L, Mueller, M, Carell, T. 登録日 2010-08-10 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Chemical Discrimination between Dc and 5Medc Via Their Hydroxylamine Adducts Nucleic Acids Res., 38, 2010
3LWM	Structure of the large fragment of thermus aquaticus DNA polymerase I in complex with a blunt-ended DNA and ddATP 分子名称: 2',3'-dideoxyadenosine triphosphate, ACETATE ION, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), ... 著者 Marx, A, Diederichs, K, Obeid, S. 登録日 2010-02-24 公開日 2010-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.186 Å) 主引用文献 Replication through an abasic DNA lesion: structural basis for adenine selectivity Embo J., 29, 2010
2XY5	Crystal structure of an artificial salen-copper basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 5'-D(*AP*GP*GP*GP*AP*SAYP*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*SAYP*TP*CP*CP*CP*TP)-3', ... 著者 Kaul, C, Mueller, M, Wagner, M, Schneider, S, Carell, T. 登録日 2010-11-15 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Reversible Bond Formation Enables the Replication and Amplification of a Crosslinking Salen Complex as an Orthogonal Base Pair. Nature Chem., 3, 2011
3HT3	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus V713P mutant bound to G:dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', ... 著者 Wu, E.Y, Beese, L.S. 登録日 2009-06-11 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. J.Biol.Chem., 286, 2011
3HPO	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus Y714S mutant bound to G:T mismatch 分子名称: 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', 5'-D(P*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', DNA polymerase I, ... 著者 Wu, E.Y, Beese, L.S. 登録日 2009-06-04 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. J.Biol.Chem., 286, 2011
3HP6	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus F710Y mutant bound to G:T mismatch 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*CP*CP*GP*TP*GP*AP*TP*CP*G)-3', 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DDG))-3', ... 著者 Wu, E.Y, Beese, L.S. 登録日 2009-06-03 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. J.Biol.Chem., 286, 2011
2Y1I	Crystal structure of a S-diastereomer analogue of the spore photoproduct in complex with fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: 5'-D(*AP*GP*GP*GP*PBTP*THM*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*AP*CP*CP*CP*TP)-3', DNA POLYMERASE I, ... 著者 Heil, K, Schneider, S, Mueller, M, Kneuttinger, A.C, Carell, T. 登録日 2010-12-08 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the Uv-Induced Spore Photoproduct DNA Lesion. Chemistry, 17, 2011
1NK7	GUANINE-ADENINE MISMATCH AT THE POLYMERASE ACTIVE SITE 分子名称: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
1NKE	A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A CYTOSINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP. 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I, DNA PRIMER STRAND, ... 著者 Johnson, S.J, Beese, L.S. 登録日 2003-01-02 公開日 2004-03-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
3LWL	Structure of Klenow fragment of Taq polymerase in complex with an abasic site 分子名称: 2',3'-dideoxyadenosine triphosphate, ACETATE ION, DNA (5'-D(*AP*AP*AP*(3DR)P*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... 著者 Marx, A, Diederichs, K, Obeid, S. 登録日 2010-02-24 公開日 2010-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Replication through an abasic DNA lesion: structural basis for adenine selectivity Embo J., 29, 2010

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