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2Y1J	CRYSTAL STRUCTURE OF A R-DIASTEREOMER ANALOGUE OF THE SPORE PHOTOPRODUCT IN COMPLEX WITH FRAGMENT DNA POLYMERASE I FROM BACILLUS STEAROTHERMOPHILUS 分子名称: 5'-D(*AP*GP*GP*GP*QBTP*THM*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*AP*CP*CP*CP*TP)-3', DNA POLYMERASE I, ... 著者 Heil, K, Schneider, S, Mueller, M, Kneuttinger, A.C, Carell, T. 登録日 2010-12-08 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the Uv-Induced Spore Photoproduct DNA Lesion. Chemistry, 17, 2011
2Y1I	Crystal structure of a S-diastereomer analogue of the spore photoproduct in complex with fragment DNA polymerase I from Bacillus stearothermophilus 分子名称: 5'-D(*AP*GP*GP*GP*PBTP*THM*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*AP*CP*CP*CP*TP)-3', DNA POLYMERASE I, ... 著者 Heil, K, Schneider, S, Mueller, M, Kneuttinger, A.C, Carell, T. 登録日 2010-12-08 公開日 2011-07-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the Uv-Induced Spore Photoproduct DNA Lesion. Chemistry, 17, 2011
6UR2	DNA polymerase I Large Fragment from Bacillus stearothermophilus with DNA template and primer containing an N3'-> P5' linkage 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*(C42)P*G)-3'), DNA (5'-D(P*AP*CP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I 著者 Zhang, W, Lelyveld, V.S, Szostak, J.W. 登録日 2019-10-21 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proc.Natl.Acad.Sci.USA, 117, 2020
7K5U	Bst DNA polymerase I time-resolved structure, 48 hr post dATP and dCTP addition 分子名称: DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
7K5P	Bst DNA polymerase I time-resolved structure, 4 min post dATP addition 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
7K5S	Bst DNA polymerase I time-resolved structure, 4 hr post dATP and dCTP addition 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
7K5O	Bst DNA polymerase I time-resolved structure, 1 min post dATP addition 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
7K5R	Bst DNA polymerase I time-resolved structure, 120 min post dATP addition 分子名称: DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
7K5Q	Bst DNA polymerase I time-resolved structure, 8 min post dATP addition 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*G*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... 著者 Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. 登録日 2020-09-17 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
3BDP	DNA POLYMERASE I/DNA COMPLEX 分子名称: DNA (5'-D(*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*CP*2DT)-3'), PROTEIN (DNA POLYMERASE I), ... 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1997-11-17 公開日 1999-01-13 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
1L3S	Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA. 分子名称: 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3', DNA Polymerase I, ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-03-01 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
1L3U	Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue. 分子名称: 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', DNA Polymerase I, ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-03-01 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
1L5U	Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue. 分子名称: 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3', DNA Polymerase I, ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-03-08 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
1L3V	Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 15 base pairs of duplex DNA following addition of dTTP, dATP, dCTP, and dGTP residues. 分子名称: 5'-D(*GP*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*CP*GP*TP*C)-3', DNA Polymerase I, ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-03-01 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
1L3T	Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 10 base pairs of duplex DNA following addition of a single dTTP residue 分子名称: 5'-D(*GP*AP*CP*G*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3', DNA Polymerase I, ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-03-01 公開日 2003-03-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
1LV5	Crystal Structure of the Closed Conformation of Bacillus DNA Polymerase I Fragment Bound to DNA and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*TP*CP*GP*CP*TP*GP*AP*TP*CP*CP*G)-3', 5'-D(*GP*GP*AP*TP*CP*AP*GP*CP*GP*A)-3', ... 著者 Johnson, S.J, Taylor, J.S, Beese, L.S. 登録日 2002-05-24 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
8SCN	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h (Product State) 分子名称: CALCIUM ION, DIPHOSPHATE, DNA polymerase I, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCJ	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCS	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCU	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State) 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCI	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCM	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCR	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCK	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCL	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 6h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023

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