3BND
 
 | | Lipoxygenase-1 (Soybean), I553V Mutant | | 分子名称: | FE (III) ION, Seed lipoxygenase-1 | | 著者 | Tomchick, D.R. | | 登録日 | 2007-12-14 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3DY5
 | | Allene oxide synthase 8R-lipoxygenase from Plexaura homomalla | | 分子名称: | Allene oxide synthase-lipoxygenase protein, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Gilbert, N.C, Niebuhr, M, Tsuruta, H, Newcomer, M.E. | | 登録日 | 2008-07-25 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | | 主引用文献 | A covalent linker allows for membrane targeting of an oxylipin biosynthetic complex.
Biochemistry, 47, 2008
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1LOX
 | | RABBIT RETICULOCYTE 15-LIPOXYGENASE | | 分子名称: | (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID, 15-LIPOXYGENASE, FE (II) ION | | 著者 | Gillmor, S.A, Villasenor, A, Fletterick, R.J, Sigal, E, Browner, M.F. | | 登録日 | 1997-10-06 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat.Struct.Biol., 4, 1997
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3BNE
 | | Lipoxygenase-1 (Soybean) I553A Mutant | | 分子名称: | FE (III) ION, Seed lipoxygenase-1 | | 著者 | Tomchick, D.R. | | 登録日 | 2007-12-14 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3FG3
 | | Crystal structure of Delta413-417:GS I805W LOX | | 分子名称: | ACETIC ACID, Allene oxide synthase-lipoxygenase protein, CALCIUM ION, ... | | 著者 | Neau, D.B, Newcomer, M.E. | | 登録日 | 2008-12-04 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.
Biochemistry, 48, 2009
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3BNB
 | | Lipoxygenase-1 (Soybean) I553L Mutant | | 分子名称: | FE (III) ION, Seed lipoxygenase-1 | | 著者 | Tomchick, D.R. | | 登録日 | 2007-12-14 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1JNQ
 | | LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH EPIGALLOCATHECHIN (EGC) | | 分子名称: | 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL, FE (II) ION, lipoxygenase-3 | | 著者 | Zhou, K, Skrzypczak-Jankun, E, Jankun, J. | | 登録日 | 2001-07-24 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibition of lipoxygenase by (-)-epigallocatechin gallate: X-ray analysis at 2.1 A reveals degradation of EGCG
and shows soybean LOX-3 complex with EGC instead.
INT.J.MOL.MED., 12, 2003
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1RRH
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1ROV
 | | Lipoxygenase-3 Treated with Cumene Hydroperoxide | | 分子名称: | FE (III) ION, Seed lipoxygenase-3 | | 著者 | Vahedi-Faridi, A, Brault, P.A, Shah, P, Kim, Y.W, Dunham, W.R, Funk, M.O. | | 登録日 | 2003-12-02 | | 公開日 | 2004-03-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition
J.Am.Chem.Soc., 126, 2004
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3BNC
 | | Lipoxygenase-1 (Soybean) I553G Mutant | | 分子名称: | ACETIC ACID, FE (III) ION, Seed lipoxygenase-1 | | 著者 | Tomchick, D.R. | | 登録日 | 2007-12-14 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1N8Q
 | | LIPOXYGENASE IN COMPLEX WITH PROTOCATECHUIC ACID | | 分子名称: | 3,4-DIHYDROXYBENZOIC ACID, FE (II) ION, lipoxygenase-3 | | 著者 | Borbulevych, O.Y, Jankun, J, Selman, S.H, Skrzypczak-Jankun, E. | | 登録日 | 2002-11-21 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 A resolution.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
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3V99
 | | S663D Stable-5-LOX in complex with Arachidonic Acid | | 分子名称: | ARACHIDONIC ACID, Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E. | | 登録日 | 2011-12-23 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | | 主引用文献 | Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
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1RRL
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7SOJ
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7SOI
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5T5V
 | | LIPOXYGENASE-1 (SOYBEAN) AT 293K | | 分子名称: | FE (III) ION, Seed linoleate 13S-lipoxygenase-1 | | 著者 | Poss, E.M, Fraser, J.S. | | 登録日 | 2016-08-31 | | 公開日 | 2017-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.
ACS Cent Sci, 3, 2017
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7TTJ
 | | Stable-5-LOX elongated Ha2 | | 分子名称: | Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Gilbert, N.C, Newcomer, M.E. | | 登録日 | 2022-02-01 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Helical remodeling augments 5-lipoxygenase activity in the synthesis of proinflammatory mediators.
J.Biol.Chem., 298, 2022
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7TTL
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5TQN
 | | Lipoxygenase-1 (soybean) L546A mutant at 293K | | 分子名称: | FE (II) ION, Seed linoleate 13S-lipoxygenase-1 | | 著者 | Poss, E.M, Fraser, J.S, Gee, C. | | 登録日 | 2016-10-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
J.Am.Chem.Soc., 141, 2019
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7TTK
 | | Stable-5-LOX | | 分子名称: | Arachidonate 5-lipoxygenase, FE (II) ION | | 著者 | Gilbert, N.C, Newcomer, M.E. | | 登録日 | 2022-02-01 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Stable-5-LOX "closed"
To Be Published
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5TQO
 | | Lipoxygenase-1 (soybean) L546A/L754A mutant at 300K | | 分子名称: | FE (III) ION, Seed linoleate 13S-lipoxygenase-1 | | 著者 | Poss, E.M, Fraser, J.S, Gee, C. | | 登録日 | 2016-10-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
J.Am.Chem.Soc., 141, 2019
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5TR0
 | | Lipoxygenase-1 (soybean) L754A mutant at 293K | | 分子名称: | FE (II) ION, Seed linoleate 13S-lipoxygenase-1 | | 著者 | Poss, E.M, Fraser, J.S. | | 登録日 | 2016-10-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
J.Am.Chem.Soc., 141, 2019
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5TQP
 | | LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT AT 300K | | 分子名称: | FE (III) ION, Seed linoleate 13S-lipoxygenase-1 | | 著者 | Poss, E.M, Fraser, J.S. | | 登録日 | 2016-10-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.
ACS Cent Sci, 3, 2017
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1FGT
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1F8N
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