PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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8HOQ	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Phe(4CF3)-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Phe(4CF3)-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOP	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Nap-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Nap-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOU	Crystal structure of the P450 BM3 heme domain mutant F87A-T268V in complex with Im-N-C4-Phe-Phe 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-N-C4-Phe-Phe, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOT	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with NH2-C7-Phe-Phe 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, NH2-C7-Phe-Phe, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A in complex with NH2-C7-Phe-Phe To Be Published
8HON	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Tyr-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Tyr-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOS	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Phe(4NO2)-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Phe(4NO2)-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOO	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Tyr-Nap 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Tyr-Nap, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Tyr-Nap To Be Published
8HNZ	Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 6FCWP 分子名称: (3~{S},8~{a}~{S})-3-[(5-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, Cytochrome P450-F5053, ... 著者 Ma, B.D, Tian, W, Qu, X, Kong, X.D. 登録日 2022-12-09 公開日 2023-04-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines. Angew.Chem.Int.Ed.Engl., 62, 2023
8HO1	Crystal structure of cytochrome P450 NasF5053 mutant F387G 分子名称: CALCIUM ION, Cytochrome P450-F5053, PROTOPORPHYRIN IX CONTAINING FE 著者 Ma, B.D, Tian, W, Qu, X, Kong, X.D. 登録日 2022-12-09 公開日 2023-04-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines. Angew.Chem.Int.Ed.Engl., 62, 2023
8HO0	Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 8FCWP 分子名称: (3~{S},8~{a}~{S})-3-[(7-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, Cytochrome P450-F5053, ... 著者 Ma, B.D, Tian, W, Qu, X, Kong, X.D. 登録日 2022-12-09 公開日 2023-04-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines. Angew.Chem.Int.Ed.Engl., 62, 2023
8HNY	Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 5FCWP 分子名称: (3~{S},8~{a}~{S})-3-[(4-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cytochrome P450-F5053, PROTOPORPHYRIN IX CONTAINING FE 著者 Ma, B.D, Tian, W, Qu, X, Kong, X.D. 登録日 2022-12-09 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines. Angew.Chem.Int.Ed.Engl., 62, 2023
8FDA	Human Cytochrome P450 17A1 in complex with steroidal isonitrile inhibitor 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase, [(1~{R})-1-[(3~{S},5~{S},8~{R},9~{S},10~{S},13~{S},17~{R})-3-methanoyloxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,13,14,15,16,17-hexadecahydrocyclopenta[a]phenanthren-17-yl]ethyl]-methylidyne-azanium 著者 Richard, A.M, Scott, E.E. 登録日 2022-12-02 公開日 2023-08-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selective steroidogenic cytochrome P450 haem iron ligation by steroid-derived isonitriles. Commun Chem, 6, 2023
8FBC	Crystal structure of P450T2 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Pereira, J.H, Huang, J, Keasling, J, Adams, P.D. 登録日 2022-11-29 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Complete integration of carbene-transfer chemistry into biosynthesis. Nature, 617, 2023
8HKJ	Crystal structure of the CYP102A5 haem Domain isolated from Bacillus cereus 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE 著者 Stanfield, J.K, Onoda, H, Sugimoto, H, Shoji, O. 登録日 2022-11-27 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily. J.Inorg.Biochem., 245, 2023
8HKD	Crystal structure of P450BSbeta-L78G/Q85F/F173S/G290I variant in complex with palmitoleic acid 分子名称: DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, PALMITOLEIC ACID, ... 著者 He, C, Wang, X, Li, F. 登録日 2022-11-25 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Biocatalytic enantioselective gamma-C-H lactonization of aliphatic carboxylic acids Nat Synth, 2023
8F91	OxyB, a cytochrome P450 involved in keratinimicin biosynthesis 分子名称: OxyB, PROTOPORPHYRIN IX CONTAINING FE 著者 Ireland, K.A, Davis, K.M. 登録日 2022-11-22 公開日 2023-07-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Robust Chemoenzymatic Synthesis of Keratinimicin Aglycone Analogues Facilitated by the Structure and Selectivity of OxyB. Acs Chem.Biol., 18, 2023
8HGT	Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Tian, X, Cong, Z. 登録日 2022-11-15 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Enabling Peroxygenase Activity in Cytochrome P450 Monooxygenases by Engineering Hydrogen Peroxide Tunnels. J.Am.Chem.Soc., 145, 2023
8HGB	Crystal structure of the CYP199A4 mutant F182G in complex with 3-hydroxy-4-methoxybenzoic acid 分子名称: 4-methoxy-3-oxidanyl-benzoic acid, Cytochrome P450, GLYCEROL, ... 著者 Jiang, Y, Cong, Z. 登録日 2022-11-14 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of the CYP199A4 mutant F182G in complex with 3-hydroxy-4-methoxybenzoic acid To Be Published
8HGD	Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei 分子名称: Cytochrome P450, GLYCEROL, METHANOL, ... 著者 Jiang, Y, Cong, Z. 登録日 2022-11-14 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei To Be Published
8HGE	Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei in complex with 12-hydroxydodecanoic acid 分子名称: 12-HYDROXYDODECANOIC ACID, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Cong, Z. 登録日 2022-11-14 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei in complex with 12-hydroxydodecanoic acid To Be Published
8HG9	Cytochrome P450 steroid hydroxylase (BaCYP106A6) from Bacillus species 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 steroid hydroxylase 著者 Do, H, Lee, J.H. 登録日 2022-11-14 公開日 2023-07-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase ( Ba CYP106A6) from Bacillus Species. J Microbiol Biotechnol., 33, 2023
8HGC	Crystal structure of the CYP199A4 mutant F182T in complex with 4-methoxybenzoic acid 分子名称: 4-METHOXYBENZOIC ACID, ACETATE ION, Cytochrome P450, ... 著者 Jiang, Y, Cong, Z. 登録日 2022-11-14 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Enabling Peroxygenase Activity in Cytochrome P450 Monooxygenases by Engineering Hydrogen Peroxide Tunnels. J.Am.Chem.Soc., 145, 2023
8EXB	Crystal structure of CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, {N-[([2,2'-bipyridin]-5-yl-kappa~2~N~1~,N~1'~)methyl]-3-(pyridin-3-yl)propanamide}bis[2-(quinolin-2-yl-kappaN)-1-benzothiophen-3-yl-kappaC~3~]iridium(1+) 著者 Sevrioukova, I.F. 登録日 2022-10-25 公開日 2023-02-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4. Inorg.Chem., 62, 2023
8EWP	Crystal structure of CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, {N-[([2,2'-bipyridin]-5-yl-kappa~2~N~1~,N~1'~)methyl]-3-(pyridin-4-yl)propanamide}bis[2-(quinolin-2-yl-kappaN)-1-benzothiophen-3-yl-kappaC~3~]iridium(1+) 著者 Sevrioukova, I.F. 登録日 2022-10-24 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4. Inorg.Chem., 62, 2023
8EWR	Crystal structure of CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, {tert-butyl [1-{[([2,2'-bipyridin]-5-yl-kappa~2~N~1~,N~1'~)methyl]amino}-1-oxo-3-(pyridin-4-yl)propan-2-yl]carbamate}bis[2-(quinolin-2-yl-kappaN)phenyl-kappaC~1~]iridium(1+) 著者 Sevrioukova, I.F. 登録日 2022-10-24 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4. Inorg.Chem., 62, 2023

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