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3P7R
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Radiation damage study of thermolysin - 100K structure C (4.9 MGy)
分子名称: CALCIUM ION, Thermolysin, ZINC ION
著者Juers, D.H, Weik, M.
登録日2010-10-12
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Radiation damage study of thermolysin - 100K structure C (4.9 MGy)
To be Published
2PF4
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BU of 2pf4 by Molmil
Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit
分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION
著者Cho, U, Morrone, S, Xu, W.
登録日2007-04-03
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of PP2A inhibition by small t antigen.
Plos Biol., 5, 2007
2A3Q
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BU of 2a3q by Molmil
X-Ray Structure of Protein from Mus Musculus MM.29898
分子名称: hypothetical protein
著者Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG)
登録日2005-06-25
公開日2005-07-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献X-Ray Structure of Protein from Mus Musculus MM.29898
To be Published
3P8I
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BU of 3p8i by Molmil
Y351F mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule
分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase
著者Toogood, H.S, Scrutton, N.S.
登録日2010-10-14
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins
Catalysis Science and Technology, 2011
2AA2
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BU of 2aa2 by Molmil
Mineralocorticoid Receptor with Bound Aldosterone
分子名称: ALDOSTERONE, GLYCEROL, Mineralocorticoid receptor, ...
著者Bledsoe, R.K, Madauss, K.P, Holt, J.A, Apolito, C.J, Lambert, M.H, Pearce, K.H, Stanley, T.B, Stewart, E.L, Trump, R.P, Willson, T.M, Williams, S.P.
登録日2005-07-13
公開日2005-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor
J.Biol.Chem., 280, 2005
2GU2
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BU of 2gu2 by Molmil
Crystal Structure of an Aspartoacylase from Rattus norvegicus
分子名称: Aspa protein, SULFATE ION, ZINC ION
著者Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-28
公開日2006-06-20
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3P9M
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BU of 3p9m by Molmil
Crystal Structure of H2-Kb in complex with a mutant of the chicken ovalbumin epitope OVA-G4
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J.
登録日2010-10-18
公開日2011-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses
J.Immunol., 187, 2011
3OMU
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BU of 3omu by Molmil
Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative
分子名称: 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, Heat shock protein 83
著者Wernimont, A.K, Hutchinson, A, Sullivan, H, Weadge, J, Cossar, D, Li, Y, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Wyatt, P.G, Fairlamb, A.H, MacKenzie, C, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC)
登録日2010-08-27
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013
3OIV
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BU of 3oiv by Molmil
H-RasG12V with allosteric switch in the "off" state
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
著者Buhrman, G, Mattos, C.
登録日2010-08-20
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.837 Å)
主引用文献Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase.
J.Biol.Chem., 286, 2011
3OKL
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BU of 3okl by Molmil
Crystal structure of S25-39 in complex with Kdo(2.8)Kdo
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ...
著者Blackler, R.J, Evans, S.V.
登録日2010-08-25
公開日2011-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity.
Biochemistry, 50, 2011
3OMP
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Fragment-Based Design of novel Estrogen Receptor Ligands
分子名称: 2-(trifluoroacetyl)-1,2,3,4-tetrahydroisoquinolin-7-ol, Estrogen receptor beta, Nuclear receptor coactivator 1
著者Moecklinghoff, S, van Otterlo, W.A, Rose, R, Fuchs, S, Dominguez Seoane, M, Waldmann, H, Ottmann, C, Brunsveld, L.
登録日2010-08-27
公開日2011-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach.
J.Med.Chem., 54, 2011
3ON6
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BU of 3on6 by Molmil
Crystal structure of an exo-alpha-1,6-mannosidase (bacova_03626) from bacteroides ovatus at 1.70 a resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-08-27
公開日2010-09-15
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a Bacterial protein of unknown function (BACOVA_03626) from Bacteroides ovatus at 1.70 A resolution
To be published
3OV4
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Crystal Structure of Ketosteroid Isomerase P39GV40GS42G from Pseudomonas Testosteroni (tKSI) bound to Equilenin
分子名称: EQUILENIN, SULFATE ION, Steroid Delta-isomerase
著者Gonzalez, A, Tsai, Y, Schwans, J, Sunden, F, Herschlag, D.
登録日2010-09-15
公開日2011-10-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal Structure of Ketosteroid Isomerase P39GV40GS42G from Pseudomonas Testosteroni (tKSI)
To be Published
3OVL
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BU of 3ovl by Molmil
Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, ACETIC ACID, Microtubule-associated protein, ...
著者Landau, M, Eisenberg, D.
登録日2010-09-16
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
1Y82
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BU of 1y82 by Molmil
Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
分子名称: UNKNOWN ATOM OR ION, hypothetical protein
著者Horanyi, P, Tempel, W, Habel, J, Chen, L, Lee, D, Nguyen, D, Chang, S.-H, Florence, Q, Zhou, W, Lin, D, Zhang, H, Praissman, J, Jenney Jr, F.E, Adams, M.W.W, Liu, Z.-J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-10
公開日2005-01-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
To be published
2OQQ
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BU of 2oqq by Molmil
Crystal structure of HY5 leucine zipper homodimer from Arabidopsis thaliana
分子名称: Transcription factor HY5
著者Yoon, M.-K, Kim, H.M, Choi, G, Lee, J.-O, Choi, B.-S.
登録日2007-02-01
公開日2007-03-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the conformational integrity of the Arabidopsis thaliana HY5 leucine zipper homodimer.
J.Biol.Chem., 282, 2007
3OW8
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BU of 3ow8 by Molmil
Crystal Structure of the WD repeat-containing protein 61
分子名称: UNKNOWN ATOM OR ION, WD repeat-containing protein 61
著者Tempel, W, Li, Z, Chao, X, Lam, R, Wernimont, A.K, He, H, Seitova, A, Pan, P.W, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-09-17
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
2HBJ
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BU of 2hbj by Molmil
Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain
分子名称: Exosome complex exonuclease RRP6
著者Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E.
登録日2006-06-14
公開日2006-07-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3OZ6
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BU of 3oz6 by Molmil
Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
分子名称: GLYCEROL, Mitogen-activated protein kinase 1, serine/threonine protein kinase
著者Wernimont, A.K, Lew, J, Lin, Y.H, Sullivan, H, Hassanali, A, Kozieradzki, I, Cossar, D, Arrowsmith, C.H, Bochkarev, A, Bountra, C, Edwards, A.M, Weigelt, J, Hui, R, Neculai, A.M, Hutchinson, A, Structural Genomics Consortium (SGC)
登録日2010-09-24
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
To be Published
3OZC
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Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase in complex with pCl-phenylthioDADMeImmA
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, PHOSPHATE ION, S-methyl-5'-thioadenosine phosphorylase
著者Ho, M, Guan, R, Almo, S.C, Schramm, V.L.
登録日2010-09-24
公開日2011-09-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase
to be published
3P1D
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BU of 3p1d by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with N-Methyl-2-pyrrolidone (NMP)
分子名称: 1-methylpyrrolidin-2-one, CREB-binding protein, POTASSIUM ION, ...
著者Filippakopoulos, P, Picaud, S, Feletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2010-09-30
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3P20
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Crystal structure of vanadate bound subunit A of the A1AO ATP synthase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ...
著者Manimekalai, M.S.S, Kumar, A, Jeyakanthan, J, Gruber, G.
登録日2010-10-01
公開日2011-03-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The transition-like state and Pi entrance into the catalytic a subunit of the biological engine A-ATP synthase.
J.Mol.Biol., 408, 2011
3LKN
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Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LKY
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BU of 3lky by Molmil
Monomeric Griffithsin with a Single Gly-Ser Insertion
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
3LL2
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Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010

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