PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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7KEF	RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state 分子名称: (1S)-1,4-anhydro-1-(3-methoxynaphthalen-2-yl)-5-O-phosphono-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Wang, D. 登録日 2020-10-10 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.89 Å) 主引用文献 Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
7KEE	RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site 分子名称: (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Wang, D. 登録日 2020-10-10 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
5U2O	Crystal structure of Zn-binding triple mutant of GH family 9 endoglucanase J30 分子名称: CITRATE ANION, GLYCEROL, J30 CCH, ... 著者 Ellinghaus, T.L, Pereira, J.H, McAndrew, R.P, Welner, D.H, Adams, P.D. 登録日 2016-11-30 公開日 2018-05-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Engineering glycoside hydrolase stability by the introduction of zinc binding. Acta Crystallogr D Struct Biol, 74, 2018
2WZF	Legionella pneumophila glucosyltransferase crystal structure 分子名称: GLUCOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... 著者 Hurtado-Guerrero, R, Zusman, T, Pathak, S, Ibrahim, A.F.M, Shepherd, S, Prescott, A, Segal, G, van Aalten, D.M.F. 登録日 2009-11-29 公開日 2009-12-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular Mechanism of Elongation Factor 1A Inhibition by a Legionella Pneumophila Glycosyltransferase. Biochem.J., 426, 2010
1PNF	PNGASE F COMPLEX WITH DI-N-ACETYLCHITOBIOSE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F, SULFATE ION 著者 Van Roey, P, Kuhn, P. 登録日 1995-10-11 公開日 1996-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F. J.Biol.Chem., 270, 1995
4PYQ	Humanized rat apo-COMT in complex with a ureido-benzamidine 分子名称: 4-({[3-(aminomethyl)phenyl]carbamoyl}amino)benzenecarboximidamide, ACETATE ION, CHLORIDE ION, ... 著者 Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2014-03-27 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70, 2014
4PW2	Crystal structure of D-glucuronyl C5 epimerase 分子名称: CITRIC ACID, D-glucuronyl C5 epimerase B 著者 Ke, J, Qin, Y, Gu, X, Brunzelle, J.S, Xu, H.E, Ding, K. 登録日 2014-03-18 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290, 2015
3VQ7	HIV-1 IN core domain in complex with 4-(1H-pyrrol-1-yl)aniline 分子名称: 4-(1H-pyrrol-1-yl)aniline, CADMIUM ION, POL polyprotein, ... 著者 Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. 登録日 2012-03-20 公開日 2013-01-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
7KRI	FR6-bound SARS-CoV-2 Nsp9 RNA-replicase 分子名称: 1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione, MALONATE ION, Non-structural protein 9, ... 著者 Littler, D.R, Gully, B.S, Rossjohn, J. 登録日 2020-11-20 公開日 2021-07-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9. J.Biol.Chem., 297, 2021
3VQA	HIV-1 IN core domain in complex with 1-benzothiophen-6-amine 1,1-dioxide 分子名称: 1-benzothiophen-6-amine 1,1-dioxide, CADMIUM ION, POL polyprotein, ... 著者 Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. 登録日 2012-03-20 公開日 2013-01-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
4HIZ	Phage phi92 endosialidase 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Schwarzer, D, Browning, C, Leiman, P.G. 登録日 2012-10-12 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Crystal Structure of Endosialidase from Phage phi92 that cleaves alpha2,8- and alpha2,9-linked polysialic acid To be Published
6TQF	The structure of ABC transporter Rv1819c in AMP-PNP bound state 分子名称: ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... 著者 Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. 登録日 2019-12-16 公開日 2020-04-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds. Nature, 580, 2020
3IJ9	Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase 分子名称: (2R,3S,4R,5R,6R)-2,6-difluoro-2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, CALCIUM ION, CHLORIDE ION, ... 著者 Li, C, Zhang, R, Withers, S.G, Brayer, G.D. 登録日 2009-08-04 公開日 2009-10-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase Biochemistry, 48, 2009
4PYJ	human apo-COMT, single domain swap 分子名称: CHLORIDE ION, Catechol O-methyltransferase, MAGNESIUM ION, ... 著者 Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2014-03-27 公開日 2014-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70, 2014
4PYO	Humanized rat COMT bound to SAH, semi-holo form 分子名称: Catechol O-methyltransferase, MAGNESIUM ION, POTASSIUM ION, ... 著者 Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2014-03-27 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70, 2014
3VSZ	Crystal structure of Ct1,3Gal43A in complex with galactan 分子名称: GLYCEROL, Ricin B lectin, beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, ... 著者 Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. 登録日 2012-05-18 公開日 2012-12-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.893 Å) 主引用文献 Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
4QLM	ydao riboswitch binding to c-di-AMP 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, RNA (108-MER), ... 著者 Ren, A.M, Patel, D.J. 登録日 2014-06-12 公開日 2014-08-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.721 Å) 主引用文献 c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nat.Chem.Biol., 10, 2014
2UUI	Crystal structure of Human Leukotriene C4 Synthase 分子名称: DODECYL-BETA-D-MALTOSIDE, LEUKOTRIENE C4 SYNTHASE, NICKEL (II) ION, ... 著者 Martinez Molina, D, Wetterholm, A, Kohl, A, McCarthy, A.A, Niegowski, D, Ohlson, E, Hammarberg, T, Eshaghi, S, Haeggstrom, J.Z, Nordlund, P. 登録日 2007-03-02 公開日 2007-07-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase. Nature, 448, 2007
7BNU	VDR complex with BXL-62 分子名称: 1,25-Dihydroxy-16-ene-20-cyclopropyl-vitamin D3, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N, Belorusova, A.Y. 登録日 2021-01-22 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants. Int J Mol Sci, 23, 2022
7BNS	VDR complex with BXL-62 分子名称: 1,25-Dihydroxy-16-ene-20-cyclopropyl-vitamin D3, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N, Belorusova, A.Y. 登録日 2021-01-22 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants. Int J Mol Sci, 23, 2022
7L2X	cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state c 分子名称: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, 1-deoxy-1-(methylamino)-D-allitol, Transient receptor potential cation channel subfamily V member 1, ... 著者 Zhang, K, Julius, D, Cheng, Y. 登録日 2020-12-17 公開日 2021-09-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184, 2021
6JG2	Crystal structure of barley exohydrolaseI wildtype in complex with 4'-nitrophenyl thiolaminaribioside 分子名称: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-nitrophenoxy)-3,5-bis(oxidanyl)oxan-4-yl]sulfanyl-oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Barley exohydrolase I, ... 著者 Luang, S, Streltsov, V.A, Hrmova, M. 登録日 2019-02-13 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
3OBV	Autoinhibited Formin mDia1 Structure 分子名称: Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose 著者 Tomchick, D.R, Rosen, M.K, Otomo, T. 登録日 2010-08-09 公開日 2010-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One, 5, 2010
4D6D	Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the blood group A-trisaccharide (X02 mutant) 分子名称: 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose 著者 Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. 登録日 2014-11-11 公開日 2014-11-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
2ZML	Crystal structure of basic winged bean lectin in complex with Gal-ALPHA 1,4 Gal 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Basic agglutinin, CALCIUM ION, ... 著者 Kulkarni, K.A, Katiyar, S, Surolia, A, Vijayan, M, Suguna, K. 登録日 2008-04-19 公開日 2008-07-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure and sugar-specificity of basic winged-bean lectin: structures of new disaccharide complexes and a comparative study with other known disaccharide complexes of the lectin. Acta Crystallogr.,Sect.D, 64, 2008

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