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7EGH
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BU of 7egh by Molmil
TFIID lobe C subcomplex
分子名称: DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ...
著者Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG8
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BU of 7eg8 by Molmil
TFIID-based core PIC on PUMA promoter
分子名称: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
登録日2021-03-24
公開日2021-05-05
最終更新日2021-05-19
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGI
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BU of 7egi by Molmil
TFIID in rearranged conformation
分子名称: TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ...
著者Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (9.82 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGD
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BU of 7egd by Molmil
SCP promoter-bound TFIID-TFIIA in initial TBP-loading state
分子名称: DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
著者Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (6.75 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGJ
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BU of 7egj by Molmil
SCP promoter-bound TFIID-TFIIA in post TBP-loading state
分子名称: DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
著者Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (8.64 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGE
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BU of 7ege by Molmil
TFIID in canonical conformation
分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
著者Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
登録日2021-03-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
7FIK
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BU of 7fik by Molmil
The cryo-EM structure of the CR subunit from X. laevis NPC
分子名称: MGC154553 protein, MGC83295 protein, MGC83926 protein, ...
著者Shi, Y, Huang, G, Zhan, X.
登録日2021-07-31
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
5QY3
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BU of 5qy3 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry B03a
分子名称: 2-[(1~{S})-1-azanylpropyl]phenol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY2
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BU of 5qy2 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A12b
分子名称: 3-(propan-2-yl)-1,2,4-oxadiazol-5(4H)-one, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY4
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BU of 5qy4 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry B08a
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY6
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BU of 5qy6 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C05a
分子名称: 2-methoxy-4-[[(4~{S},5~{S})-2,4,5-tris(2-methoxypyridin-4-yl)imidazolidin-1-yl]methyl]pyridine, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY5
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BU of 5qy5 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C02a
分子名称: 2,4,5-tris(fluoranyl)-3-methoxy-benzoic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY1
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BU of 5qy1 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry A07a
分子名称: (2-aminopyridin-3-yl)methanol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY7
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BU of 5qy7 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C08a
分子名称: (1S,3S)-2-methyl-2,3-dihydro-1H-isoindole-1,3-diol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QYB
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BU of 5qyb by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a
分子名称: (3-methoxyphenyl)(pyrrolidin-1-yl)methanone, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QYA
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BU of 5qya by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D02a
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, R-1,2-PROPANEDIOL, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY9
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BU of 5qy9 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C11b
分子名称: A1 cistron-splicing factor AAR2, N-ethyl-N-(thiophene-2-carbonyl)-beta-alanine, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QY8
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BU of 5qy8 by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry C10a
分子名称: 1,3-benzodioxole-5-carbothioamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QYC
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BU of 5qyc by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D07a
分子名称: 2-fluoranyl-~{N}-(furan-2-ylmethyl)benzenesulfonamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QYD
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BU of 5qyd by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E05a
分子名称: 2-(2-methylphenyl)acetamide, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QYE
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BU of 5qye by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E12a
分子名称: (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020

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件を2024-08-14に公開中

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