9G5H
 
 | | p53-Y220C Core Domain Covalently Bound to 2-chloro-5-cyanopyrazine Soaked at 5 mM | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-chloranylpyrazine-2-carbonitrile, ... | | 著者 | Stahlecker, J, Klett, T, Stehle, T, Boeckler, F.M. | | 登録日 | 2024-07-17 | | 公開日 | 2025-06-11 | | 最終更新日 | 2025-07-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | S N Ar Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes.
Drug Des Devel Ther, 19, 2025
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1MQR
 | | THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE (E386Q) FROM BACILLUS STEAROTHERMOPHILUS T-6 | | 分子名称: | ALPHA-D-GLUCURONIDASE, GLYCEROL | | 著者 | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | | 登録日 | 2002-09-17 | | 公開日 | 2003-09-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS.
J.Biol.Chem., 279, 2004
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9G6U
 | | p53-Y220C Core Domain Covalently Bound to 3,5-Dichloro-6-Ethylpyrazine-2-carbonitirle Soaked at 5 mM | | 分子名称: | 1,2-ETHANEDIOL, 3,5-bis(chloranyl)-6-ethyl-pyrazine-2-carbonitrile, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Stahlecker, J, Klett, T, Stehle, T, Boeckler, F.M. | | 登録日 | 2024-07-19 | | 公開日 | 2025-06-11 | | 最終更新日 | 2025-07-16 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | S N Ar Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes.
Drug Des Devel Ther, 19, 2025
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1LV0
 | | Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide | | 分子名称: | GERAN-8-YL GERAN, RAB GDP disossociation inhibitor alpha, SULFATE ION | | 著者 | An, Y, Shao, Y, Alory, C, Matteson, J, Sakisaka, T, Chen, W, Gibbs, R.A, Wilson, I.A, Balch, W.E. | | 登録日 | 2002-05-23 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Geranylgeranyl switching regulates GDI-Rab GTPase recycling.
Structure, 11, 2003
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9GD8
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1MM9
 | | Streptavidin Mutant with Insertion of Fibronectin Hexapeptide, including RGD | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Streptavidin | | 著者 | Le Trong, I, McDevitt, T.C, Nelson, K.E, Stayton, P.S, Stenkamp, R.E. | | 登録日 | 2002-09-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin.
Acta Crystallogr.,Sect.D, 59, 2003
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7RKB
 | | Crystal Structure of Putative Pterin Binding Protein (PruR) from Klebsiella pneumoniae in Complex with Neopterin | | 分子名称: | CHLORIDE ION, L-NEOPTERIN, Pterin Binding Protein, ... | | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-07-22 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Putative Pterin Binding Protein (PruR) from Klebsiella pneumoniae in Complex with Neopterin.
To Be Published
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9G27
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site, pre-translocation state | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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1MMC
 | | 1H NMR STUDY OF THE SOLUTION STRUCTURE OF AC-AMP2 | | 分子名称: | ANTIMICROBIAL PEPTIDE 2 | | 著者 | Martins, J.C, Maes, D, Loris, R, Pepermans, H.A.M, Wyns, L, Willem, R, Verheyden, P. | | 登録日 | 1995-10-25 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus.
J.Mol.Biol., 258, 1996
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9G1X
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site, 11-subunit | | 分子名称: | DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, DNA-directed RNA polymerase I subunit RPA190, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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2PEH
 | | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | | 分子名称: | Splicing factor 3B subunit 1, Splicing factor 45 | | 著者 | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
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1MMW
 | | Rat neuronal NOS heme domain with vinyl-L-NIO bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N5-(1-IMINO-3-BUTENYL)-L-ORNITHINE, ... | | 著者 | Bretscher, L.E, Li, H, Poulos, T.L, Griffith, O.W. | | 登録日 | 2002-09-04 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines
J.Biol.Chem., 278, 2003
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9G2B
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site, 12-subunit | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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9G23
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site bound to nucleotide analog AMPCPP at A-site | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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1MNA
 | | Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.0 | | 分子名称: | polyketide synthase IV | | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | | 登録日 | 2002-09-05 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
Biochemistry, 41, 2002
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9G29
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site with the C-terminal of A12 in the funnel | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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7ROM
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9G24
 | | Yeast RNA polymerase I elongation complex stalled by an apurinic site bound to nucleotide analog AMPCPP at E-site | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ... | | 著者 | Santos-Aledo, A, Plaza-Pegueroles, A, Ruiz, F.M, Fernandez-Tornero, C. | | 登録日 | 2024-07-10 | | 公開日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions.
Nat Commun, 16, 2025
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9GBY
 | | Crystal structure of Pseudomonas aeruginosa IspD | | 分子名称: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, POTASSIUM ION | | 著者 | Borel, F, D'Auria, L. | | 登録日 | 2024-07-31 | | 公開日 | 2025-06-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Fragment Discovery by X-Ray Crystallographic Screening Targeting the CTP Binding Site of Pseudomonas Aeruginosa IspD.
Angew.Chem.Int.Ed.Engl., 64, 2025
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1LX6
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7RHP
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1MNQ
 | | Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.4 | | 分子名称: | polyketide synthase IV | | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | | 登録日 | 2002-09-05 | | 公開日 | 2003-02-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
Biochemistry, 41, 2002
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1MO8
 | | ATPase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Sodium/Potassium-Transporting ATPase alpha-1 | | 著者 | Hilge, M, Siegal, G, Vuister, G.W, Guentert, P, Gloor, S.M, Abrahams, J.P. | | 登録日 | 2002-09-08 | | 公開日 | 2003-06-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase
Nat.Struct.Biol., 10, 2003
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9GTP
 | | Cryo-EM structure of a contractile injection system in Streptomyces coelicolor, the baseplate complex in extended state applied 6-fold symmetry. | | 分子名称: | Baseplate protein J-like domain-containing protein, IraD/Gp25-like domain-containing protein, LysM domain-containing protein, ... | | 著者 | Casu, B, Sallmen, J.W, Haas, P.E, Afanasyev, P, Xu, J, Schlimpert, S, Pilhofer, M. | | 登録日 | 2024-09-18 | | 公開日 | 2025-06-18 | | 最終更新日 | 2025-07-16 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA.
Elife, 14, 2025
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1MQ7
 | | CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | | 著者 | Sawaya, M.R, Chan, S, Segelke, B.W, Lekin, T, Heike, K, Cho, U.S, Naranjo, C, Perry, L.J, Yeates, T.O, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-09-13 | | 公開日 | 2002-10-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
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