PDB: 1396 件ウェブページステータス検索Chemie searchBIRD

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3V51	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor RM-1-176 分子名称: 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-15 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
3V5P	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1288 分子名称: 3-(4-methoxy-3-methylphenyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
3V5T	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1299 分子名称: 1-[(2S)-2-(dimethylamino)-3-methylbutyl]-3-(6-ethoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
6DMU	PI(4,5)P2 bound full-length rbTRPV5 分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2018-06-05 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9, 2018
3UPZ	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumpless BKI analog UW1243 分子名称: 1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-11-18 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
3HKO	Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40 分子名称: Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands, GLYCEROL, MAGNESIUM ION, ... 著者 Wernimont, A.K, Hutchinson, A, Wasney, G, Vedadi, M, MacKenzie, F, Kozieradzki, I, Cossar, D, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Botchkarev, A, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC) 登録日 2009-05-25 公開日 2009-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40 To be Published
7URW	Tetradecameric hub domain of CaMKII beta 分子名称: Calcium/calmodulin-dependent protein kinase type II subunit beta 著者 Ozden, C, Samkutty, A, Stratton, M.M, Garman, S.C. 登録日 2022-04-22 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Tetradecameric hub domain of CaMKII beta To Be Published
7URZ	Hexadecameric hub domain of CaMKII beta 分子名称: Calcium/calmodulin-dependent protein kinase type II subunit beta 著者 Ozden, C, Samkutty, A, Stratton, M.M, Garman, S.C. 登録日 2022-04-22 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Hexadecameric hub domain of CaMKII beta To Be Published
8J07	96nm repeat of human respiratory doublet microtubule and associated axonemal complexes 分子名称: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ... 著者 Gui, M, Brown, A. 登録日 2023-04-09 公開日 2023-07-26 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature, 618, 2023
7TZC	A drug and ATP binding site in type 1 ryanodine receptor 分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R. 登録日 2022-02-15 公開日 2022-05-18 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 A drug and ATP binding site in type 1 ryanodine receptor. Structure, 30, 2022
5C1V	CRYSTAL STRUCTURE ANALYSIS OF CATALYTIC SUBUNIT OF HUMAN CALCINEURIN 分子名称: FE (III) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, ... 著者 Guasch, A, Fita, I, Perez-Luque, R, Aparicio, D, Aranguren-Ibanez, A, Perez-Riba, M. 登録日 2015-06-15 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization. Plos One, 10, 2015
2YAA	Crystal structure of the autoinhibited form of mouse DAPK2 in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DEATH-ASSOCIATED PROTEIN KINASE 2, ... 著者 Patel, A.K, Kursula, P. 登録日 2011-02-18 公開日 2011-04-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Dimeric Autoinhibited Conformation of Dapk2, a Pro-Apoptotic Protein Kinase. J.Mol.Biol., 409, 2011
2YA9	Crystal structure of the autoinhibited form of mouse DAPK2 分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, CALCIUM ION, DEATH-ASSOCIATED PROTEIN KINASE 2 著者 Patel, A.K, Kursula, P. 登録日 2011-02-18 公開日 2011-04-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Dimeric Autoinhibited Conformation of Dapk2, a Pro-Apoptotic Protein Kinase. J.Mol.Biol., 409, 2011
2XUU	Crystal structure of a DAP-kinase 1 mutant 分子名称: ADENOSINE-5'-DIPHOSPHATE, DEATH-ASSOCIATED PROTEIN KINASE 1, MAGNESIUM ION, ... 著者 de Diego, I, Kuper, J, Lehmann, F, Wilmanns, M. 登録日 2010-10-21 公開日 2011-11-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity. Chem.Biol., 21, 2014
2YAB	Crystal structure of the autoinhibited form of mouse DAPK2 in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, CALCIUM ION, DEATH-ASSOCIATED PROTEIN KINASE 2, ... 著者 Patel, A.K, Kursula, P. 登録日 2011-02-18 公開日 2011-04-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Dimeric Autoinhibited Conformation of Dapk2, a Pro-Apoptotic Protein Kinase. J.Mol.Biol., 409, 2011
1QX2	X-ray Structure of Calcium-loaded Calbindomodulin (A Calbindin D9k Re-engineered to Undergo a Conformational Opening) at 1.44 A Resolution 分子名称: CALCIUM ION, Vitamin D-dependent calcium-binding protein, intestinal, ... 著者 Bunick, C.G, Nelson, M.R, Mangahas, S, Mizoue, L.S, Bunick, G.J, Chazin, W.J. 登録日 2003-09-04 公開日 2004-05-25 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Designing Sequence to Control Protein Function in an EF-Hand Protein J.Am.Chem.Soc., 126, 2004
1SJJ	Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin 分子名称: actinin 著者 Liu, J, Taylor, D.W, Taylor, K.A. 登録日 2004-03-03 公開日 2004-03-23 最終更新日 2024-02-14 実験手法 ELECTRON CRYSTALLOGRAPHY (20 Å) 主引用文献 A 3-D Reconstruction of Smooth Muscle alpha-Actinin by CryoEm Reveals Two Different Conformations at the Actin-binding Region. J.Mol.Biol., 338, 2004
3F3Z	Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804 分子名称: 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one, Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, GLYCEROL 著者 Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Cossar, D, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC) 登録日 2008-10-31 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804 To be Published
5JQA	CaM:RM20 complex 分子名称: CALCIUM ION, Calmodulin, Myosin light chain kinase, ... 著者 Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. 登録日 2016-05-04 公開日 2017-10-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 CaM:RM20 complex To be Published
6NID	Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain in complex with Neurexin-1 peptide 分子名称: 1,2-ETHANEDIOL, Neurexin-1, Peripheral plasma membrane protein CASK 著者 Sun, Y.J, Gakhar, L, Fuentes, E.J. 登録日 2018-12-27 公開日 2020-01-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 CASK PDZ domain specificity To be published
7SQC	Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii 分子名称: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ... 著者 Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R. 登録日 2021-11-05 公開日 2022-04-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ciliary central apparatus structure reveals mechanisms of microtubule patterning. Nat.Struct.Mol.Biol., 29, 2022
6NH9	Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain 分子名称: Peripheral plasma membrane protein CASK 著者 Sun, Y.J, Gakhar, L, Fuentes, E.J. 登録日 2018-12-21 公開日 2019-12-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 CASK PDZ domain specificity To be published
6C1D	High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. 登録日 2018-01-04 公開日 2018-01-31 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3LIJ	Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP 分子名称: CALCIUM ION, Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, MAGNESIUM ION, ... 著者 Qiu, W, Hutchinson, A, Wernimont, A, Walker, J.R, Sullivan, H, Lin, Y.-H, Mackenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) 登録日 2010-01-25 公開日 2010-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP To be Published
4PJJ	MYOSIN VI (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state - long soaking with PO4 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... 著者 Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. 登録日 2014-05-12 公開日 2015-04-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015

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