4MY4
 
 | | Crystal structure of phosphoglycerate mutase from Staphylococcus aureus. | | 分子名称: | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, MANGANESE (II) ION | | 著者 | Roychowdhury, A, Kundu, A, Gujar, A, Bose, M, Das, A.K. | | 登録日 | 2013-09-27 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
Febs J., 282, 2015
|
|
4Y6G
 | | Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and beta-site. | | 分子名称: | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | | 著者 | Hilario, E, Caulkins, B.G, Young, R.P, Dunn, M.F, Mueller, L.J, Fan, L. | | 登録日 | 2015-02-13 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water.
Biochim.Biophys.Acta, 1864, 2016
|
|
3V16
 | | An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, CHLORIDE ION | | 著者 | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | | 登録日 | 2011-12-09 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop
Biochemistry, 51, 2012
|
|
4YRO
 | |
2JDL
 | | Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin | | 分子名称: | ACIDIC RIBOSOMAL PROTEIN P2, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN | | 著者 | Too, P.H, Mak, A.N, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C. | | 登録日 | 2007-01-11 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome.
Nucleic Acids Res., 37, 2009
|
|
4YRL
 | |
7JS4
 | |
4YP0
 | |
4YRJ
 | | Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 4-chlorobenzene-1,2-diamine (Chem 256) | | 分子名称: | 1,2-ETHANEDIOL, 4-chlorobenzene-1,2-diamine, DIMETHYL SULFOXIDE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-03-15 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
|
|
4YRE
 | |
8A2H
 | | human STING in complex with 2',3'-cyclic-GMP-7-deazaphenyl-AMP | | 分子名称: | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanyl-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, Stimulator of interferon genes protein | | 著者 | Smola, M, Vavrina, Z, Boura, E, Brynda, J. | | 登録日 | 2022-06-03 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
J.Med.Chem., 65, 2022
|
|
4YRF
 | | Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 5-bromopyridin-2(1H)-one (Chem 148) | | 分子名称: | 1,2-ETHANEDIOL, 5-bromopyridin-2(1H)-one, DIMETHYL SULFOXIDE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-03-15 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
4YRN
 | |
2GC1
 | |
8ADT
 | | Rational design of a calcium-independent trypsin variant | | 分子名称: | Serine protease 1 | | 著者 | Simon, A.H, Liebscher, S, Kattner, A, Kattner, C, Bordusa, F. | | 登録日 | 2022-07-11 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Rational Design of a Calcium-Independent Trypsin Variant
Catalysts, 12, 2022
|
|
4YIT
 | |
8AWG
 | | small molecule stabilizer for ERalpha and 14-3-3 (1074202) | | 分子名称: | 14-3-3 protein sigma, 2-chloranyl-~{N}-[[1-[2-(4-chloranylphenoxy)-2-methyl-propanoyl]piperidin-4-yl]methyl]ethanamide, Estrogen receptor, ... | | 著者 | Konstantinidou, M, Visser, E.J, Vandenboorn, E.M.F, Sheng, C, Jaishankar, P, Overmans, M.J.A.M, Dutta, S, Neitz, J, Renslo, A, Ottmann, C, Brunsveld, L, Arkin, M. | | 登録日 | 2022-08-29 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3 sigma /ER alpha Protein-Protein Interaction from Nonselective Fragments.
J.Am.Chem.Soc., 145, 2023
|
|
4LHI
 | |
7LBU
 | | Crystal structure of the Propionibacterium acnes surface sialidase | | 分子名称: | ACETATE ION, Exo-alpha-sialidase, PHOSPHATE ION | | 著者 | Yu, A.C.Y, Volkers, G, Strynadka, N.C.J. | | 登録日 | 2021-01-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Glycobiology, 32, 2022
|
|
7LBV
 | | Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Exo-alpha-sialidase, PHOSPHATE ION | | 著者 | Yu, A.C.Y, Volkers, G, Strynadka, N.C.J. | | 登録日 | 2021-01-09 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Glycobiology, 32, 2022
|
|
1VA4
 | | Pseudomonas fluorescens aryl esterase | | 分子名称: | Arylesterase, GLYCEROL | | 著者 | Cheeseman, J.D, Tocilj, A, Park, S, Schrag, J.D, Kazlauskas, R.J. | | 登録日 | 2004-02-11 | | 公開日 | 2004-07-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | | 主引用文献 | Structure of an aryl esterase from Pseudomonas fluorescens.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
4YPF
 | |
4YRT
 | |
4YRG
 | |
4YRQ
 | |
