4BPW
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![BU of 4bpw by Molmil](/molmil-images/mine/4bpw) | Crystal structure of human primase bound to UTP | 分子名称: | DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ... | 著者 | Kilkenny, M.L, Perera, R.L, Pellegrini, L. | 登録日 | 2013-05-28 | 公開日 | 2013-09-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering Proc.Natl.Acad.Sci.USA, 110, 2013
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4C7N
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![BU of 4c7n by Molmil](/molmil-images/mine/4c7n) | Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of MITF | 分子名称: | MERCURY (II) ION, MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR, SYNTHETIC ALPHA-HELIX, ... | 著者 | Wohlwend, D, Gerhardt, S, Kuekenshoener, T, Einsle, O. | 登録日 | 2013-09-23 | 公開日 | 2014-04-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Improving Coiled Coil Stability While Maintaining Specificity by a Bacterial Hitchhiker Selection System. J.Struct.Biol., 186, 2014
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4C3D
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![BU of 4c3d by Molmil](/molmil-images/mine/4c3d) | HRSV M2-1, P422 crystal form | 分子名称: | CADMIUM ION, MATRIX M2-1 | 著者 | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | 登録日 | 2013-08-22 | 公開日 | 2014-01-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation. Proc.Natl.Acad.Sci.USA, 111, 2014
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4C3B
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![BU of 4c3b by Molmil](/molmil-images/mine/4c3b) | HRSV M2-1, P21 crystal form | 分子名称: | MATRIX PROTEIN 2-1, ZINC ION | 著者 | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | 登録日 | 2013-08-22 | 公開日 | 2014-01-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CNC
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![BU of 4cnc by Molmil](/molmil-images/mine/4cnc) | Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | 著者 | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | 登録日 | 2014-01-21 | 公開日 | 2014-02-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4CNM
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![BU of 4cnm by Molmil](/molmil-images/mine/4cnm) | Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | 著者 | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | 登録日 | 2014-01-23 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4CPB
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![BU of 4cpb by Molmil](/molmil-images/mine/4cpb) | CRYSTAL STRUCTURE OF LECA IN COMPLEX WITH A DIVALENT GALACTOSIDE AT 1. 57 ANGSTROM IN MAGNESIUM | 分子名称: | (4S)-N-ethyl-4-{[N-methyl-3-(1-{2-[(4-sulfanylbenzoyl)amino]ethyl}-1H-1,2,3-triazol-4-yl)-L-alanyl]amino}-L-prolinamide, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Topin, J, Varrot, A, Imberty, A, Wissinger, N. | 登録日 | 2014-02-04 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | A Leca Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion by Pseudomonas Aeruginosa. Angew.Chem.Int.Ed.Engl., 53, 2014
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4CPZ
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![BU of 4cpz by Molmil](/molmil-images/mine/4cpz) | Structure of the Neuraminidase from the B/Lyon/CHU/15.216/2011 virus in complex with Zanamivir | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | 登録日 | 2014-02-09 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses. J.Infect.Dis., 210, 2014
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4CYJ
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![BU of 4cyj by Molmil](/molmil-images/mine/4cyj) | Chaetomium thermophilum Pan2:Pan3 complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ... | 著者 | Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A. | 登録日 | 2014-04-11 | 公開日 | 2014-06-11 | 最終更新日 | 2014-07-30 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation Embo J., 33, 2014
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4CUR
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![BU of 4cur by Molmil](/molmil-images/mine/4cur) | Crystal structure of human BAZ2B in complex with fragment-3 N09555 | 分子名称: | 1,2-ETHANEDIOL, 2-(hydroxymethyl)-6-methylpyridin-3-ol, BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B | 著者 | Bradley, A.R, Liu, Y, Krojer, T, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, von Delft, F. | 登録日 | 2014-03-21 | 公開日 | 2014-04-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | 主引用文献 | Crystal Structure of Human Baz2B in Complex with Fragment-3 N09553 To be Published
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4CA1
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![BU of 4ca1 by Molmil](/molmil-images/mine/4ca1) | Crystal structure of Siah1 at 1.58 A resolution. | 分子名称: | CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE SIAH1, GLYCEROL, ... | 著者 | Rimsa, V, Eadsforth, T.C, Hunter, W.N. | 登録日 | 2013-10-04 | 公開日 | 2013-10-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Two High-Resolution Structures of the Human E3 Ubiquitin Ligase Siah1. Acta Crystallogr.,Sect.F, 96, 2013
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4CAI
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![BU of 4cai by Molmil](/molmil-images/mine/4cai) | Structure of inner DysF domain of human dysferlin | 分子名称: | DYSFERLIN, PHOSPHATE ION | 著者 | Sula, A, Cole, A.R, Yeats, C, Orengo, C, Keep, N.H. | 登録日 | 2013-10-08 | 公開日 | 2014-01-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures of the Human Dysferlin Inner Dysf Domain Bmc Struct.Biol., 14, 2014
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4CCA
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![BU of 4cca by Molmil](/molmil-images/mine/4cca) | Structure of human Munc18-2 | 分子名称: | CHLORIDE ION, SYNTAXIN-BINDING PROTEIN 2 | 著者 | Hackmann, Y, Graham, S.C, Ehl, S, Hoening, S, Lehmberg, K, Arico, M, Owen, D.J, Griffiths, G.G. | 登録日 | 2013-10-21 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Syntaxin Binding Mechanism and Disease-Causing Mutations in Munc18-2 Proc.Natl.Acad.Sci.USA, 110, 2013
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4C0M
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![BU of 4c0m by Molmil](/molmil-images/mine/4c0m) | Crystal Structure of the N terminal domain of wild type TRIF (TIR- domain-containing adapter-inducing interferon-beta) | 分子名称: | TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 | 著者 | Ullah, M.O, Ve, T, Mangan, M, Alaidarous, M, Sweet, M.J, Mansell, A, Kobe, B. | 登録日 | 2013-08-05 | 公開日 | 2013-12-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Tlr Signalling Adaptor Trif/Ticam-1 Has an N-Terminal Helical Domain with Structural Similarity to Ifit Proteins Acta Crystallogr.,Sect.D, 69, 2013
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4C3S
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![BU of 4c3s by Molmil](/molmil-images/mine/4c3s) | Structure of a propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment | 分子名称: | ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | 著者 | Marles-Wright, J, Crawshaw, A, Ang, T.F, Altenbach, K. | 登録日 | 2013-08-27 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Insight Into Coenzyme a Cofactor Binding and the Mechanism of Acyl-Transfer in an Acylating Aldehyde Dehydrogenase from Clostridium Phytofermentans. Sci.Rep., 6, 2016
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4C9X
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![BU of 4c9x by Molmil](/molmil-images/mine/4c9x) | Crystal structure of NUDT1 (MTH1) with S-crizotinib | 分子名称: | 3-[(1S)-1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY]-5-(1-PIPERIDIN-4-YLPYRAZOL-4-YL)PYRIDIN-2-AMINE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, CHLORIDE ION, ... | 著者 | Elkins, J.M, Salah, E, Huber, K, Superti-Furga, G, Abdul Azeez, K.R, Krojer, T, von Delft, F, Bountra, C, Edwards, A, Knapp, S. | 登録日 | 2013-10-03 | 公開日 | 2014-04-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Stereospecific Targeting of Mth1 by (S)-Crizotinib as an Anticancer Strategy. Nature, 508, 2014
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4C3C
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![BU of 4c3c by Molmil](/molmil-images/mine/4c3c) | Thaumatin refined against hatrx data for time-point 1 | 分子名称: | L(+)-TARTARIC ACID, THAUMATIN-1 | 著者 | Yorke, B.A, Beddard, G.S, Owen, R.L, Pearson, A.R. | 登録日 | 2013-08-22 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Time-Resolved Crystallography Using the Hadamard Transform. Nat.Methods, 11, 2014
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4C41
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![BU of 4c41 by Molmil](/molmil-images/mine/4c41) | |
4C9Q
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![BU of 4c9q by Molmil](/molmil-images/mine/4c9q) | Structure of yeast mitochondrial ADP/ATP carrier isoform 3 inhibited by carboxyatractyloside (P21 crystal form) | 分子名称: | ADP, ATP CARRIER PROTEIN 3, CARDIOLIPIN, ... | 著者 | Ruprecht, J.J, Hellawell, A.M, Harding, M, Crichton, P.G, McCoy, A.J, Kunji, E.R.S. | 登録日 | 2013-10-02 | 公開日 | 2014-01-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of Yeast Mitochondrial Adp/ATP Carriers Support a Domain-Based Alternating-Access Transport Mechanism Proc.Natl.Acad.Sci.USA, 111, 2014
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4CBO
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![BU of 4cbo by Molmil](/molmil-images/mine/4cbo) | |
8P0J
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![BU of 8p0j by Molmil](/molmil-images/mine/8p0j) | |
5Q0E
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![BU of 5q0e by Molmil](/molmil-images/mine/5q0e) | FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(4S,8S)-8-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-4-methyl-2-oxo-1,3,4,5,6,7,8,10-octahydro-2H-12,9-(azeno)-1,10-benzodiazacyclotetradecin-15-yl]carbamate | 分子名称: | 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ... | 著者 | Sheriff, S. | 登録日 | 2017-05-01 | 公開日 | 2017-07-12 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency. Bioorg. Med. Chem. Lett., 27, 2017
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4CZ1
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![BU of 4cz1 by Molmil](/molmil-images/mine/4cz1) | Crystal structure of kynurenine formamidase from Bacillus anthracis complexed with 2-aminoacetophenone. | 分子名称: | 2-aminoacetophenone, KYNURENINE FORMAMIDASE, MAGNESIUM ION, ... | 著者 | Diaz-Saez, L, Srikannathasan, V, Zoltner, M, Hunter, W.N. | 登録日 | 2014-04-16 | 公開日 | 2014-04-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structure of Bacterial Kynurenine Formamidase Reveals a Crowded Binuclear-Zinc Catalytic Site Primed to Generate a Potent Nucleophile. Biochem.J., 462, 2014
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4CZZ
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![BU of 4czz by Molmil](/molmil-images/mine/4czz) | Histone demethylase LSD1(KDM1A)-CoREST3 Complex | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 3 | 著者 | Barrios, A.P, Gomez, A.V, Saez, J.E, Ciossani, G, Toffolo, E, Battaglioli, E, Mattevi, A, Andres, M.E. | 登録日 | 2014-04-23 | 公開日 | 2014-06-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Differential Properties of Transcriptional Complexes Formed by the Corest Family. Mol.Cell.Biol., 34, 2014
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4D0S
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![BU of 4d0s by Molmil](/molmil-images/mine/4d0s) | Mtb InhA complex with Pyradizinone compound 14 | 分子名称: | 1-{4-[(acetylamino)methyl]phenyl}-4-(4-chlorophenoxy)-6-oxo-1,6-dihydropyridazine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ... | 著者 | Read, J.A, Breed, J, Madhavapeddi, P, Lange, S. | 登録日 | 2014-04-29 | 公開日 | 2015-05-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Pyridazinones: A Novel Scaffold with Excellent Physicochemical Properties and Safety Profile for a Clinically Validated Target of Mycobacterium Tuberculosis To be Published
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