8R74
 
 | | Galectin-1 in complex with thiogalactoside derivative | | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(2-oxidanyl-1,3-thiazol-4-yl)-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-1 | | 著者 | Hakansson, M, Diehl, C, Peterson, K, Zetterberg, F, Nilsson, U. | | 登録日 | 2023-11-23 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer.
J.Med.Chem., 67, 2024
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3L4A
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5UZM
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3L47
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3L4L
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5UZG
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6XOB
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1HDD
 | | CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS | | 分子名称: | DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*C P*CP*TP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN) | | 著者 | Kissinger, C.R, Liu, B, Martin-Blanco, E, Kornberg, T.B, Pabo, C.O. | | 登録日 | 1991-09-16 | | 公開日 | 1992-01-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 63, 1990
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5VNY
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3N7H
 | | Crystal structure of Odorant Binding Protein 1 from Anopheles gambiae (AgamOBP1) with DEET (N,N-Diethyl-meta-toluamide) and PEG | | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Tsitsanou, K.E, Zographos, S.E. | | 登録日 | 2010-05-27 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents.
Cell.Mol.Life Sci., 69, 2012
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3OGV
 | | Complex structure of beta-galactosidase from Trichoderma reesei with PETG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-phenylethyl 1-thio-beta-D-galactopyranoside, ... | | 著者 | Maksimainen, M, Rouvinen, J. | | 登録日 | 2010-08-17 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structures of Trichoderma reesei beta-galactosidase reveal conformational changes in the active site
J.Struct.Biol., 174, 2011
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7DXH
 | | Cryo-EM structure of PSII intermediate Psb28-PSII complex | | 分子名称: | (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 5-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-HEPTAMETHYLOCTACOSA-2,6,10,14,18,22,26-HEPTAENYL]-2,3-DIMETHYLBENZO-1,4-QUINONE, ... | | 著者 | Sui, S.F, Shen, J.R, Han, G.Y, Xiao, Y.N, Huang, G.Q. | | 登録日 | 2021-01-18 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structural insights into cyanobacterial photosystem II intermediates associated with Psb28 and Tsl0063.
Nat.Plants, 7, 2021
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1HOM
 | | DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | | 分子名称: | ANTENNAPEDIA PROTEIN | | 著者 | Qian, Y.-Q, Billeter, M, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | | 登録日 | 1991-10-08 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 214, 1990
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7DXA
 | | PSII intermediate Psb28-RC47 | | 分子名称: | (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 5-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-HEPTAMETHYLOCTACOSA-2,6,10,14,18,22,26-HEPTAENYL]-2,3-DIMETHYLBENZO-1,4-QUINONE, ... | | 著者 | Sui, S.F, Shen, J.R, Han, G.Y, Xiao, Y.N, Huang, G.Q. | | 登録日 | 2021-01-18 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structural insights into cyanobacterial photosystem II intermediates associated with Psb28 and Tsl0063.
Nat.Plants, 7, 2021
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5W3D
 | | The structure of kinesin-14 wild-type Ncd-ADP dimer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein claret segregational | | 著者 | Park, H.W, Ma, Z, Chacko, J, Jiang, S.M, Robinson, R.C, Endow, S.A. | | 登録日 | 2017-06-07 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
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3PM2
 | | Crystal structure of a novel type of odorant binding protein from Anopheles gambiae belonging to the c+ class | | 分子名称: | Odorant binding protein (AGAP007287-PA) | | 著者 | Spinelli, S, Lagarde, A, Qiao, H, Tegoni, M, Pelosi, P, Cambillau, C. | | 登録日 | 2010-11-16 | | 公開日 | 2011-05-25 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a novel type of odorant-binding protein from Anopheles gambiae, belonging to the C-plus class.
Biochem.J., 437, 2011
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3PZF
 | | 1.75A resolution structure of Serpin-2 from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, An, C, Michel, K. | | 登録日 | 2010-12-14 | | 公開日 | 2011-02-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes.
Proteins, 79, 2011
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5VO5
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9C0O
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9AT8
 | | Fab 77-stabilized MeV F ectodomain fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ... | | 著者 | Zyla, D, Saphire, E.O. | | 登録日 | 2024-02-26 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Science, 384, 2024
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6TUU
 | | Leishmania infantum Rad51 surrogate LiRadA10 in complex with 5,6,7,8-tetrahydro-2-naphthoic acid | | 分子名称: | 5,6,7,8-tetrahydronaphthalene-2-carboxylic acid, CHLORIDE ION, DNA repair and recombination protein RadA, ... | | 著者 | Pantelejevs, T, Hyvonen, M. | | 登録日 | 2020-01-08 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Development of dedicated crystallographic systems for structure-guided drug discovery
To Be Published
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8YE0
 | | Crystal structure of KgpF prenyltransferase | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ... | | 著者 | Hamada, K, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2024-02-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands.
Angew.Chem.Int.Ed.Engl., 2024
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4XGO
 | | Crystal structure of leucine-rich repeat domain of APL1B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Anopheles Plasmodium-responsive Leucine-rich repeat protein 1B, ... | | 著者 | Williams, M, Summers, B, Baxter, R.H.G. | | 登録日 | 2015-01-01 | | 公開日 | 2015-04-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Biophysical Analysis of Anopheles gambiae Leucine-Rich Repeat Proteins APL1A1, APLB and APL1C and Their Interaction with LRIM1.
Plos One, 10, 2015
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6QP7
 | | Drosophila Semaphorin 2a | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Robinson, R.A, Rozbesky, D, Harlos, K, Siebold, C, Jones, E.Y. | | 登録日 | 2019-02-13 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
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4XD0
 | | X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens | | 分子名称: | (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | | 著者 | Thoden, J.B, Woodford, C.R, Holden, H.M. | | 登録日 | 2014-12-18 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens.
Biochemistry, 54, 2015
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