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5KFB
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BU of 5kfb by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFM
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BU of 5kfm by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
分子名称: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFW
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BU of 5kfw by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFI
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BU of 5kfi by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 120s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFT
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BU of 5kft by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 40s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG5
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BU of 5kg5 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
4EJS
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BU of 4ejs by Molmil
Structure of yeast elongator subcomplex Elp456
分子名称: Elongator complex protein 4, Elongator complex protein 5, Elongator complex protein 6
著者Lin, Z, Zhao, W, Long, J, Shen, Y.
登録日2012-04-07
公開日2012-05-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.606 Å)
主引用文献Crystal structure of elongator subcomplex Elp4-6
J.Biol.Chem., 287, 2012
2R07
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BU of 2r07 by Molmil
STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(5-(6-CHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2R04
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BU of 2r04 by Molmil
STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2R06
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BU of 2r06 by Molmil
STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
2DB9
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BU of 2db9 by Molmil
Solution structure of the plus-3 domain of human KIAA0252 protein
分子名称: Paf1/RNA polymerase II complex component
著者Yoneyama, M, Kigawa, T, Tochio, N, Nameki, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-15
公開日2006-06-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the plus-3 domain of human KIAA0252 protein
To be Published
1EAH
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BU of 1eah by Molmil
PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973
分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4
著者Lentz, K, Arnold, E.
登録日1997-07-22
公開日1998-09-16
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes.
Structure, 5, 1997
2M14
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BU of 2m14 by Molmil
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and Rad4
分子名称: DNA repair protein RAD4, RNA polymerase II transcription factor B subunit 1
著者Lafrance-Vanasse, J, Arseneault, G, Cappadocia, L, Legault, P, Omichinski, J.G.
登録日2012-11-16
公開日2013-01-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER.
Nucleic Acids Res., 41, 2013
4ATG
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BU of 4atg by Molmil
TAF6 C-terminal domain from Antonospora locustae
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, TAF6
著者Romier, C.
登録日2012-05-07
公開日2012-06-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献TFIID Taf6-Taf9 Complex Formation Involves the Heat Repeat-Containing C-Terminal Domain of Taf6 and is Modulated by Taf5 Protein.
J.Biol.Chem., 287, 2012
6THL
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BU of 6thl by Molmil
Crystal structure of the complex between RTT106 and BCD1
分子名称: Box C/D snoRNA protein 1, Rtt106p
著者Charron, C, Bragantini, B, Manival, X, Charpentier, B.
登録日2019-11-20
公開日2020-12-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity.
Nat Commun, 12, 2021
2KWT
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BU of 2kwt by Molmil
Solution structure of NS2 [27-59]
分子名称: Protease NS2-3
著者Montserret, R, Bartenschlager, R, Penin, F.
登録日2010-04-19
公開日2011-03-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.
Plos Pathog., 6, 2010
2KWZ
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BU of 2kwz by Molmil
Solution structure of NS2 [60-99]
分子名称: Protease NS2-3
著者Montserret, R, Bartenschlager, R, Penin, F.
登録日2010-04-22
公開日2011-03-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.
Plos Pathog., 6, 2010
2EYQ
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BU of 2eyq by Molmil
Crystal structure of Escherichia coli transcription-repair coupling factor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Transcription-repair coupling factor
著者Deaconescu, A.M, Darst, S.A.
登録日2005-11-09
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for bacterial transcription-coupled DNA repair.
Cell(Cambridge,Mass.), 124, 2006
1R08
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BU of 1r08 by Molmil
STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES
分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-(HYDROXYETHYL OXYMETHYLENEOXYMETHYL) ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Badger, J, Smith, T.J, Rossmann, M.G.
登録日1988-10-03
公開日1990-01-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses.
Proteins, 6, 1989
3GJW
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BU of 3gjw by Molmil
PARP complexed with A968427
分子名称: 7-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one, Poly [ADP-ribose] polymerase 1
著者Park, C.H.
登録日2009-03-09
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)
Bioorg.Med.Chem.Lett., 19, 2009
6ALY
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BU of 6aly by Molmil
Solution structure of yeast Med15 ABD2 residues 277-368
分子名称: Mediator of RNA polymerase II transcription subunit 15
著者Tuttle, L.M, Pacheco, D, Warfield, L, Hahn, S, Klevit, R.E.
登録日2017-08-08
公開日2018-03-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Cell Rep, 22, 2018
5JW9
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BU of 5jw9 by Molmil
The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide
分子名称: AF4/FMR2 family member 4, RNA polymerase II elongation factor ELL2
著者Qi, S, Hurley, J.H.
登録日2016-05-11
公開日2017-02-08
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.
Nat Commun, 8, 2017
2B2N
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BU of 2b2n by Molmil
Structure of transcription-repair coupling factor
分子名称: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SODIUM ION, SULFATE ION, ...
著者Assenmacher, N, Wenig, K, Lammens, A, Hopfner, K.-P.
登録日2005-09-19
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs
J.Mol.Biol., 355, 2006
5XUQ
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BU of 5xuq by Molmil
Crystal structure of VDR-LBD complexed with an antagonist, 2-methylidene-19,26,27-trinor-22-(S)-butyl-1-hydroxy-25-oxo-25-(1H-pyrrol-2-yl)- vitamin D3
分子名称: (4~{S})-4-[(1~{R})-1-[(1~{R},3~{a}~{S},4~{E},7~{a}~{R})-7~{a}-methyl-4-[2-[(3~{R},5~{R})-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-1-yl]ethyl]-1-(1~{H}-pyrrol-2-yl)octan-1-one, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
著者Kato, A, Itoh, T, Yamamoto, K.
登録日2017-06-24
公開日2018-06-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of Potent Vitamin D Receptor Antagonist
To Be Published
5XZF
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BU of 5xzf by Molmil
Vitamin D receptor with a synthetic ligand ADRO1
分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,6S)-6-(1-adamantyl)-6-oxidanyl-hex-4-yn-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, FORMIC ACID, Mediator of RNA polymerase II transcription subunit 1, ...
著者Otero, R, Numoto, N, Ikura, T, Yamada, S, Mourino, A, Makishima, M, Ito, N.
登録日2017-07-12
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献25 S-Adamantyl-23-yne-26,27-dinor-1 alpha ,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex.
J. Med. Chem., 61, 2018

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件を2024-09-04に公開中

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