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3QQC
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Crystal structure of archaeal Spt4/5 bound to the RNAP clamp domain
分子名称: DNA-directed RNA polymerase subunit b, DNA-directed RNA polymerase subunit a', DNA-directed RNA polymerase subunit A'', ...
著者Martinez-Rucobo, F.W.
登録日2011-02-15
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity.
Embo J., 30, 2011
2WHO
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BU of 2who by Molmil
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR
分子名称: 2-(3-bromophenyl)-6-[(2-hydroxyethyl)amino]-1h-benzo[de]isoquinoline-1,3(2h)-dione, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Di Marco, S.
登録日2009-05-05
公開日2009-08-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.
J. Med. Chem., 52, 2009
5OHO
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BU of 5oho by Molmil
Crystal structure of the KOWx-KOW4 domain of human DSIF
分子名称: CHLORIDE ION, GLYCEROL, Transcription elongation factor SPT5
著者Bernecky, C, Plitzko, J.M, Cramer, P.
登録日2017-07-17
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.
Nat. Struct. Mol. Biol., 24, 2017
4YGX
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BU of 4ygx by Molmil
Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide
分子名称: LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide
著者Mayfield, J.E, Zhang, Y.
登録日2015-02-26
公開日2015-09-16
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
2EC0
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BU of 2ec0 by Molmil
RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP
分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2007-02-09
公開日2007-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
5OHQ
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BU of 5ohq by Molmil
Crystal structure of the KOW6-KOW7 domain of human DSIF
分子名称: CHLORIDE ION, SODIUM ION, Transcription elongation factor SPT5
著者Bernecky, C, Plitzko, J.M, Cramer, P.
登録日2017-07-17
公開日2017-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.098 Å)
主引用文献Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.
Nat. Struct. Mol. Biol., 24, 2017
3AYH
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BU of 3ayh by Molmil
Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit rpc8, DNA-directed RNA polymerase III subunit rpc9, SULFATE ION
著者Ehara, H, Sekine, S, Yokoyama, S.
登録日2011-05-06
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III
Protein Sci., 20, 2011
6XKB
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BU of 6xkb by Molmil
Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD
分子名称: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION
著者Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2020-06-26
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
7JV7
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BU of 7jv7 by Molmil
Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex
分子名称: CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ...
著者Xie, Y, Ren, Y.
登録日2020-08-20
公開日2021-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.850553 Å)
主引用文献Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
1H38
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BU of 1h38 by Molmil
Structure of a T7 RNA polymerase elongation complex at 2.9A resolution
分子名称: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ...
著者Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S.
登録日2002-08-24
公開日2002-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution
Nature, 420, 2002
6IRV
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BU of 6irv by Molmil
Crystal structure of the human cap-specific adenosine methyltransferase
分子名称: Phosphorylated CTD-interacting factor 1
著者Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2018-11-14
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
6IRW
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BU of 6irw by Molmil
Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH
分子名称: Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE
著者Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2018-11-14
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
2XI7
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BU of 2xi7 by Molmil
N-terminal endonuclease domain of La Crosse virus L-protein
分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L
著者Reguera, J, Weber, F, Cusack, S.
登録日2010-06-28
公開日2010-10-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
Plos Pathog., 6, 2010
1HQM
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BU of 1hqm by Molmil
CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K.
登録日2000-12-18
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
2XI5
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BU of 2xi5 by Molmil
N-terminal endonuclease domain of La Crosse virus L-protein
分子名称: MANGANESE (II) ION, RNA POLYMERASE L
著者Reguera, J, Weber, F, Cusack, S.
登録日2010-06-28
公開日2010-10-06
最終更新日2012-07-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
Plos Pathog., 6, 2010
5MDT
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BU of 5mdt by Molmil
Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe.
分子名称: Rpb7-binding protein seb1
著者Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J.
登録日2016-11-13
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
1NB7
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BU of 1nb7 by Molmil
HC-J4 RNA polymerase complexed with short RNA template strand
分子名称: 5'-R(*UP*UP*UP*U)-3', MANGANESE (II) ION, polyprotein
著者O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J.
登録日2002-12-02
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation.
J.Mol.Biol., 326, 2003
2PPB
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BU of 2ppb by Molmil
Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ...
著者Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R.
登録日2007-04-28
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
8T1I
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BU of 8t1i by Molmil
Atomic model of the mammalian Mediator complex with MED26 subunit
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
著者Zhao, H, Asturias, F.
登録日2023-06-02
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (4.68 Å)
主引用文献An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
To Be Published
2O5J
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BU of 2o5j by Molmil
Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate analog
分子名称: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ...
著者Vassylyev, D.G, Vassylyeva, M.N.
登録日2006-12-06
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for substrate loading in bacterial RNA polymerase.
Nature, 448, 2007
3P8B
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BU of 3p8b by Molmil
X-ray crystal structure of Pyrococcus furiosus transcription elongation factor Spt4/5
分子名称: BETA-MERCAPTOETHANOL, DNA-directed RNA polymerase, subunit e'', ...
著者Murakami, K.S, Klein, B.J.
登録日2010-10-13
公開日2011-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献RNA polymerase and transcription elongation factor Spt4/5 complex structure.
Proc.Natl.Acad.Sci.USA, 108, 2011
1NB6
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BU of 1nb6 by Molmil
HC-J4 RNA polymerase complexed with UTP
分子名称: MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, polyprotein
著者O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J.
登録日2002-12-02
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation.
J.Mol.Biol., 326, 2003
2O5I
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BU of 2o5i by Molmil
Crystal structure of the T. thermophilus RNA polymerase elongation complex
分子名称: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ...
著者Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N.
登録日2006-12-06
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for transcription elongation by bacterial RNA polymerase.
Nature, 448, 2007
7VW5
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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-11-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
1S0V
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BU of 1s0v by Molmil
Structural basis for substrate selection by T7 RNA polymerase
分子名称: 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ...
著者Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-01-05
公開日2004-02-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for substrate selection by t7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004

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