PDB: 8627 件ウェブページステータス検索Chemie searchBIRD

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3QQC	Crystal structure of archaeal Spt4/5 bound to the RNAP clamp domain 分子名称: DNA-directed RNA polymerase subunit b, DNA-directed RNA polymerase subunit a', DNA-directed RNA polymerase subunit A'', ... 著者 Martinez-Rucobo, F.W. 登録日 2011-02-15 公開日 2011-03-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. Embo J., 30, 2011
2WHO	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR 分子名称: 2-(3-bromophenyl)-6-[(2-hydroxyethyl)amino]-1h-benzo[de]isoquinoline-1,3(2h)-dione, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Di Marco, S. 登録日 2009-05-05 公開日 2009-08-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors. J. Med. Chem., 52, 2009
5OHO	Crystal structure of the KOWx-KOW4 domain of human DSIF 分子名称: CHLORIDE ION, GLYCEROL, Transcription elongation factor SPT5 著者 Bernecky, C, Plitzko, J.M, Cramer, P. 登録日 2017-07-17 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
4YGX	Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide 分子名称: LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide 著者 Mayfield, J.E, Zhang, Y. 登録日 2015-02-26 公開日 2015-09-16 最終更新日 2015-10-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
2EC0	RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-02-09 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
5OHQ	Crystal structure of the KOW6-KOW7 domain of human DSIF 分子名称: CHLORIDE ION, SODIUM ION, Transcription elongation factor SPT5 著者 Bernecky, C, Plitzko, J.M, Cramer, P. 登録日 2017-07-17 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.098 Å) 主引用文献 Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
3AYH	Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III 分子名称: DNA-directed RNA polymerase III subunit rpc8, DNA-directed RNA polymerase III subunit rpc9, SULFATE ION 著者 Ehara, H, Sekine, S, Yokoyama, S. 登録日 2011-05-06 公開日 2011-07-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.193 Å) 主引用文献 Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III Protein Sci., 20, 2011
6XKB	Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD 分子名称: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION 著者 Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2020-06-26 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4. Febs Lett., 596, 2022
7JV7	Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex 分子名称: CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ... 著者 Xie, Y, Ren, Y. 登録日 2020-08-20 公開日 2021-01-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.850553 Å) 主引用文献 Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
1H38	Structure of a T7 RNA polymerase elongation complex at 2.9A resolution 分子名称: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... 著者 Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. 登録日 2002-08-24 公開日 2002-11-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
6IRV	Crystal structure of the human cap-specific adenosine methyltransferase 分子名称: Phosphorylated CTD-interacting factor 1 著者 Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2018-11-14 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
6IRW	Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH 分子名称: Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE 著者 Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2018-11-14 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
2XI7	N-terminal endonuclease domain of La Crosse virus L-protein 分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L 著者 Reguera, J, Weber, F, Cusack, S. 登録日 2010-06-28 公開日 2010-10-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
1HQM	CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Minakhin, L, Bhagat, S, Brunning, A, Campbell, E.A, Darst, S.A, Ebright, R.H, Severinov, K. 登録日 2000-12-18 公開日 2001-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Proc.Natl.Acad.Sci.USA, 98, 2001
2XI5	N-terminal endonuclease domain of La Crosse virus L-protein 分子名称: MANGANESE (II) ION, RNA POLYMERASE L 著者 Reguera, J, Weber, F, Cusack, S. 登録日 2010-06-28 公開日 2010-10-06 最終更新日 2012-07-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
5MDT	Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe. 分子名称: Rpb7-binding protein seb1 著者 Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J. 登録日 2016-11-13 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
1NB7	HC-J4 RNA polymerase complexed with short RNA template strand 分子名称: 5'-R(*UP*UP*UP*U)-3', MANGANESE (II) ION, polyprotein 著者 O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. 登録日 2002-12-02 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
2PPB	Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ... 著者 Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R. 登録日 2007-04-28 公開日 2007-07-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
8T1I	Atomic model of the mammalian Mediator complex with MED26 subunit 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-02 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.68 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II To Be Published
2O5J	Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate analog 分子名称: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... 著者 Vassylyev, D.G, Vassylyeva, M.N. 登録日 2006-12-06 公開日 2007-07-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
3P8B	X-ray crystal structure of Pyrococcus furiosus transcription elongation factor Spt4/5 分子名称: BETA-MERCAPTOETHANOL, DNA-directed RNA polymerase, subunit e'', ... 著者 Murakami, K.S, Klein, B.J. 登録日 2010-10-13 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 RNA polymerase and transcription elongation factor Spt4/5 complex structure. Proc.Natl.Acad.Sci.USA, 108, 2011
1NB6	HC-J4 RNA polymerase complexed with UTP 分子名称: MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, polyprotein 著者 O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. 登録日 2002-12-02 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
2O5I	Crystal structure of the T. thermophilus RNA polymerase elongation complex 分子名称: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... 著者 Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N. 登録日 2006-12-06 公開日 2007-07-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for transcription elongation by bacterial RNA polymerase. Nature, 448, 2007
7VW5	Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-11-09 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
1S0V	Structural basis for substrate selection by T7 RNA polymerase 分子名称: 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... 著者 Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-01-05 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate selection by t7 RNA polymerase. Cell(Cambridge,Mass.), 116, 2004

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