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4V6K
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BU of 4v6k by Molmil
Structural insights into cognate vs. near-cognate discrimination during decoding.
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-01-07
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.25 Å)
主引用文献Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
6QHT
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BU of 6qht by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 376 ms
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
7LGW
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BU of 7lgw by Molmil
Structure of human Prestin in nanodisc in the presence of NaCl
分子名称: CHLORIDE ION, CHOLESTEROL, DECANE, ...
著者Ge, J, Gouaux, E.
登録日2021-01-21
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
6QI2
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BU of 6qi2 by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 13536 ms
分子名称: Fluoroacetate dehalogenase, GLYCOLIC ACID
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
4UYU
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BU of 4uyu by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IODIDE ION, ...
著者Zebisch, M, Jones, E.Y.
登録日2014-09-03
公開日2015-02-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
5VOD
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BU of 5vod by Molmil
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Malito, E, Chandramouli, S.
登録日2017-05-02
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Structural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Sci Immunol, 2, 2017
7LH2
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BU of 7lh2 by Molmil
Structure of human prestin in the presence of sodium salicylate and sodium sulfate
分子名称: 2-HYDROXYBENZOIC ACID, CHOLESTEROL, Prestin
著者Ge, J, Gouaux, E.
登録日2021-01-21
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Molecular mechanism of prestin electromotive signal amplification.
Cell, 184, 2021
4V6L
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BU of 4v6l by Molmil
Structural insights into cognate vs. near-cognate discrimination during decoding.
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
登録日2011-01-07
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (13.2 Å)
主引用文献Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
5DGC
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BU of 5dgc by Molmil
Reaction of phosphorylated CheY with imidazole 2 of 3
分子名称: BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, Chemotaxis protein CheY, ...
著者Page, S, Silversmith, R.E, Bourret, R.B, Collins, E.J.
登録日2015-08-27
公開日2016-03-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Imidazole as a Small Molecule Analogue in Two-Component Signal Transduction.
Biochemistry, 54, 2015
5VDA
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BU of 5vda by Molmil
Crystal structure of human WEE1 kinase domain in complex with RAC-IV-101, a MK1775 analogue
分子名称: 1,2-ETHANEDIOL, 1-{6-[(1S)-1-hydroxyethyl]pyridin-2-yl}-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ...
著者Zhu, J.-Y, Schonbrunn, E.
登録日2017-04-01
公開日2018-04-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of Wee family kinase inhibition by small molecules
to be published
2XER
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BU of 2xer by Molmil
Human PatL1 C-terminal domain (loop variant with sulfates)
分子名称: PAT1 HOMOLOG 1, SULFATE ION
著者Tritschler, F, Weichenrieder, O.
登録日2010-05-17
公開日2010-06-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
6QHP
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BU of 6qhp by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 2256 ms covalent intermediate 1
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
6QHX
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BU of 6qhx by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 6156 ms
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
4UZ7
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BU of 4uz7 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A
分子名称: CHLORIDE ION, PROTEIN NOTUM HOMOLOG
著者Zebisch, M, Jones, E.Y.
登録日2014-09-04
公開日2015-02-25
最終更新日2015-03-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
2XK1
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BU of 2xk1 by Molmil
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor
分子名称: COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, ...
著者Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2010-07-07
公開日2011-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
5VER
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BU of 5ver by Molmil
MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2Z
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
登録日2017-04-05
公開日2017-11-29
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
5VED
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BU of 5ved by Molmil
PAK4 kinase domain in complex with Staurosporine
分子名称: STAUROSPORINE, Serine/threonine-protein kinase PAK 4
著者Zhang, E.Y, Ha, B.H, Boggon, T.J.
登録日2017-04-04
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献PAK4 crystal structures suggest unusual kinase conformational movements.
Biochim. Biophys. Acta, 1866, 2018
5D18
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BU of 5d18 by Molmil
Crystal structure of Mycobacterium tuberculosis Rv0302, form I
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, SODIUM ION, ...
著者Chou, T.-H, Delmar, J, Su, C.-C, Yu, E.
登録日2015-08-04
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.
Protein Sci., 2015
7M20
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BU of 7m20 by Molmil
18-mer HeLa-tubulin rings in complex with Cryptophycin 1
分子名称: Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Eren, E.
登録日2021-03-15
公開日2021-09-08
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
5CUH
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BU of 5cuh by Molmil
Crystal structure MMP-9 complexes with a constrained hydroxamate based inhibitor LT4
分子名称: (4S)-3-{[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonyl}-N-hydroxy-1,3-thiazolidine-4-carboxamide, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Tepshi, L, Vera, L, Nuti, E, Rosalia, L, Rossello, A, Stura, E.A.
登録日2015-07-24
公開日2016-02-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Discovery of a new selective inhibitor of A Disintegrin And Metalloprotease 10 (ADAM-10) able to reduce the shedding of NKG2D ligands in Hodgkin's lymphoma cell models.
Eur.J.Med.Chem., 111, 2016
5CW1
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BU of 5cw1 by Molmil
Proteinase K complexed with 4-iodopyrazole
分子名称: 4-IODOPYRAZOLE, IODIDE ION, Proteinase K, ...
著者Bauman, J.D, Arnold, E.
登録日2015-07-27
公開日2015-12-30
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Rapid experimental SAD phasing and hot spot identification with halogenated fragments
Iucrj, 3, 2016
5VHW
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BU of 5vhw by Molmil
GluA2-0xGSG1L bound to ZK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
登録日2017-04-13
公開日2017-05-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
6QHU
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BU of 6qhu by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 100 ms
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
6QI1
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BU of 6qi1 by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 12312 ms
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
4O4J
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BU of 4o4j by Molmil
Tubulin-Peloruside A complex
分子名称: CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Prota, A.E, Bargsten, K, Northcote, P.T, Marsh, M, Altmann, K.H, Miller, J.H, Diaz, J.F, Steinmetz, M.O.
登録日2013-12-18
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of microtubule stabilization by laulimalide and peloruside A.
Angew.Chem.Int.Ed.Engl., 53, 2014

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