PDB: 2849 件ウェブページステータス検索Chemie searchBIRD

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6ALE	A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model 分子名称: (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-2, ... 著者 Nam, Y.W, Zhang, M. 登録日 2017-08-07 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model. Sci Rep, 8, 2018
1C2U	SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32 分子名称: SYNTHETIC PEPTIDE ANALOGUE OF SHK TOXIN 著者 Pennington, M.W, Lanigan, M.D, Kalman, K, Manhir, V.M, Rauer, H, McVaugh, C.T, Behm, D, Donaldson, D, Chandy, K.G, Kem, W.R, Norton, R.S. 登録日 1999-07-27 公開日 1999-11-10 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin. Biochemistry, 38, 1999
5EBW	KcsA with G77ester mutation 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-19 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
5EC2	KcsA with V76ester+G77dA mutations 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-20 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
5EC1	KcsA with V76ester mutation 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-20 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
5EBL	KcsA T75G in the Conductive State 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-19 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
5EBM	KcsA T75G mutant in the nonconductive state 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-19 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
8EP1	Eag Kv channel with voltage sensor in the down conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EOW	Eag Kv channel with voltage sensor in the up conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EP0	Eag Kv channel with voltage sensor in the intermediate conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
1BIG	SCORPION TOXIN BMTX1 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES 分子名称: TOXIN BMTX1 著者 Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H. 登録日 1998-06-16 公開日 1999-01-13 最終更新日 2019-12-25 実験手法 SOLUTION NMR 主引用文献 Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels. Biochemistry, 37, 1998
1V7F	Solution structure of phrixotoxin 1 分子名称: Phrixotoxin 1 著者 Chagot, B, Escoubas, P, Villegas, E, Bernard, C, Ferrat, G, Corzo, G, Lazdunski, M, Darbon, H. 登録日 2003-12-16 公開日 2004-11-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus Protein Sci., 13, 2004
2AHY	Na+ complex of the NaK Channel 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y. 登録日 2005-07-28 公開日 2006-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Atomic structure of a Na+- and K+-conducting channel. Nature, 440, 2006
2PTA	PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES 分子名称: PANDINUS TOXIN K-ALPHA 著者 Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J. 登録日 1996-11-26 公開日 1997-12-10 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels. Biochemistry, 36, 1997
2BMT	SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES 分子名称: TOXIN BMTX2 著者 Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H. 登録日 1998-06-16 公開日 1999-01-13 最終更新日 2019-12-25 実験手法 SOLUTION NMR 主引用文献 Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels. Biochemistry, 37, 1998
3LDC	High resolution open MthK pore structure crystallized in 100 mM K+ 分子名称: Calcium-gated potassium channel mthK, POTASSIUM ION 著者 Ye, S. 登録日 2010-01-12 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore. Nat.Struct.Mol.Biol., 17, 2010
3LDD	High resolution open MthK pore structure crystallized in 100 mM K+ and further soaked in 99 mM Na+/1 mM K+. 分子名称: Calcium-gated potassium channel mthK, POTASSIUM ION 著者 Ye, S. 登録日 2010-01-12 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore. Nat.Struct.Mol.Biol., 17, 2010
2Q68	Crystal Structure of Nak channel D66A, S70E double mutants 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Alam, A, Shi, N, Jiang, Y. 登録日 2007-06-04 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
1S6C	Crystal structure of the complex between KChIP1 and Kv4.2 N1-30 分子名称: CALCIUM ION, Kv4 potassium channel-interacting protein KChIP1b, Potassium voltage-gated channel subfamily D member 2 著者 Zhou, W, Qian, Y, Kunjilwar, K, Pfaffinger, P.J, Choe, S. 登録日 2004-01-23 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels. Neuron, 41, 2004
2Q67	Crystal Structure of Nak channel D66A mutant 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Alam, A, Shi, N, Jiang, Y. 登録日 2007-06-04 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
3JYC	Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 Angstrom resolution 分子名称: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION 著者 Tao, X. 登録日 2009-09-21 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution. Science, 326, 2009
3BEH	Structure of a Bacterial Cyclic Nucleotide Regulated Ion Channel 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Mll3241 protein, POTASSIUM ION 著者 Clayton, G.M, Morais-Cabral, J.H. 登録日 2007-11-18 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc.Natl.Acad.Sci.USA, 105, 2008
2Q69	Crystal Structure of Nak channel D66N mutant 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Alam, A, Shi, N, Jiang, Y. 登録日 2007-06-04 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q6A	Crystal Structure of Nak channel D66E mutant 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Alam, A, Shi, N, Jiang, Y. 登録日 2007-06-04 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insight into Ca2+ specificity in tetrameric cation channels. Proc.Natl.Acad.Sci.Usa, 104, 2007
3OUF	Structure of a K+ selective NaK mutant 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein 著者 Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y. 登録日 2010-09-14 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proc.Natl.Acad.Sci.USA, 108, 2011

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