1TQH
 
 | | Covalent Reaction intermediate Revealed in Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est30 | | 分子名称: | Carboxylesterase precursor, PROPYL ACETATE, SULFATE ION | | 著者 | Liu, P, Wang, Y.F, Ewis, H.E, Abdelal, A.T, Lu, C.D, Harrison, R.W, Weber, I.T. | | 登録日 | 2004-06-17 | | 公開日 | 2004-09-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Covalent reaction intermediate revealed in crystal structure of the Geobacillus stearothermophilus carboxylesterase Est30.
J.Mol.Biol., 342, 2004
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5D6T
 | | Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, SPHERULIN-4, ... | | 著者 | Bamford, N.C, Little, D.J, Howell, P.L. | | 登録日 | 2015-08-12 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.
J.Biol.Chem., 290, 2015
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7THH
 | | SUD-C and Ubl2 domains of SARS CoV-2 Nsp3 protein | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Osipiuk, J, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-01-11 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | SUD-C and Ubl2 domains of SARS CoV-2 Nsp3 protein
to be published
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4RAX
 | | A regulatory domain of an ion channel | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Ge, J, Yang, M. | | 登録日 | 2014-09-11 | | 公開日 | 2015-09-23 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Architecture of the mammalian mechanosensitive Piezo1 channel.
Nature, 527, 2015
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4QQD
 | | Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule | | 分子名称: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, E3 ubiquitin-protein ligase UHRF1, UNKNOWN ATOM OR ION | | 著者 | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2014-06-27 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
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6S6N
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6S6M
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6VEE
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6VED
 | | Solution structure of the TTD and linker region of UHRF1 | | 分子名称: | E3 ubiquitin-protein ligase UHRF1 | | 著者 | Lemak, A, Houliston, S, Duan, S, Ong, M.S, Arrowsmith, C.H. | | 登録日 | 2019-12-31 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
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2KAF
 | | Solution structure of the SARS-unique domain-C from the nonstructural protein 3 (nsp3) of the severe acute respiratory syndrome coronavirus | | 分子名称: | Non-structural protein 3 | | 著者 | Johnson, M.A, Mohanty, B, Pedrini, B, Serrano, P, Chatterjee, A, Herrmann, T, Joseph, J, Saikatendu, K, Wilson, I.A, Buchmeier, M.J, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | 登録日 | 2008-11-05 | | 公開日 | 2008-11-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding.
J.Mol.Biol., 400, 2010
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2KLU
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2K9B
 | | Structure and membrane interactions of the antibiotic peptide dermadistinctin K by multidimensional solution and oriented 15N and 31P solid-state NMR spectroscopy | | 分子名称: | Dermadistinctin-K | | 著者 | Moraes, C.M, Verly, R.M, Resende, J.M, Aisenbrey, C, Bemquerer, M.P, Pilo-Veloso, D, Valente, A, Almeida, F.C.L, Bechinger, B. | | 登録日 | 2008-10-07 | | 公開日 | 2009-04-14 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and membrane interactions of the antibiotic peptide dermadistinctin K by multidimensional solution and oriented 15N and 31P solid-state NMR spectroscopy.
Biophys.J., 96, 2009
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2KJ4
 | | Solution structure of the complex of VEK-30 and plasminogen kringle 2 | | 分子名称: | VEK-30, plasminogen | | 著者 | Wang, M, Zajicek, J, Prorok, M, Castellin, F.J. | | 登録日 | 2009-05-21 | | 公開日 | 2009-10-20 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the complex of VEK-30 and plasminogen kringle 2.
J.Struct.Biol., 169, 2010
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2KMZ
 | | NMR Structure of hFn14 | | 分子名称: | Tumor necrosis factor receptor superfamily member 12A | | 著者 | Pellegrini, M, Willen, L, Perroud, M, Krushinskie, D, Strauch, K, Cuervo, H, Sun, Y, Day, E.S, Schneider, P, Zheng, T.S. | | 登録日 | 2009-08-10 | | 公開日 | 2011-06-29 | | 最終更新日 | 2013-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
Febs J., 280, 2013
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2L0K
 | | NMR solution structure of a transcription factor SpoIIID in complex with DNA | | 分子名称: | Stage III sporulation protein D | | 著者 | Chen, B, Himes, P, Lu, Z, Liu, A, Yan, H, Kroos, L. | | 登録日 | 2010-07-08 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Novel Mode of DNA Binding by Bacterial Transcription Factor SpoIIID
To be Published
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5G59
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7L4W
 | | Crystal structure of human monoacylglycerol lipase in complex with compound 2d | | 分子名称: | (2s,4R)-2-{4-[(2-chloro-4-fluorophenoxy)methyl]piperidine-1-carbonyl}-7-oxa-5-azaspiro[3.4]octan-6-one, Monoglyceride lipase | | 著者 | Qin, L, Gay, S.C, Lane, W, Skene, R.J. | | 登録日 | 2020-12-21 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety.
J.Med.Chem., 64, 2021
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7L4U
 | | Crystal structure of human monoacylglycerol lipase in complex with compound 1h | | 分子名称: | (5S)-5-(3-{4-[(2-chloro-4-fluorophenoxy)methyl]piperidin-1-yl}-3-oxopropyl)pyrrolidin-2-one, CHLORIDE ION, Monoglyceride lipase | | 著者 | Qin, L, Lane, W, Skene, R.J, Dougan, D. | | 登録日 | 2020-12-21 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety.
J.Med.Chem., 64, 2021
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7L4T
 | | Crystal structure of human monoacylglycerol lipase in complex with compound 1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-{4-[(2-chloro-4-fluorophenoxy)methyl]piperidine-1-carbonyl}-2H-1,4-benzoxazin-3(4H)-one, ACETATE ION, ... | | 著者 | Qin, L, Gay, S.C, Lane, W, Skene, R.J. | | 登録日 | 2020-12-21 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety.
J.Med.Chem., 64, 2021
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7L50
 | | Crystal structure of human monoacylglycerol lipase in complex with compound 4f | | 分子名称: | (2s,4R)-2-{3-[(3-chloro-4-methylphenyl)methoxy]azetidine-1-carbonyl}-7-oxa-5-azaspiro[3.4]octan-6-one, ACETATE ION, Monoglyceride lipase | | 著者 | Qin, L, Lane, W, Skene, R.J. | | 登録日 | 2020-12-21 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety.
J.Med.Chem., 64, 2021
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5G5M
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1WBR
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5HLJ
 | | Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus | | 分子名称: | VP24 | | 著者 | Sun, L.F, Su, Y.T, Zhao, Y.H, Fu, Z.Q, Wu, Y.K. | | 登録日 | 2016-01-15 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | | 主引用文献 | Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus
Sci Rep, 6, 2016
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5IAY
 | | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Spacer | | 著者 | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | | 登録日 | 2016-02-22 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
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5G5C
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