PDB: 47 件ウェブページステータス検索Chemie searchBIRD

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7AI6	MutS in mismatch bound state 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein MutS 著者 Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. 登録日 2020-09-26 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
7AI7	MutS in Intermediate state 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*TP*TP*AP*GP*CP*TP*TP*AP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*TP*AP*AP*CP*TP*AP*AP*G)-3'), ... 著者 Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. 登録日 2020-09-26 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
7AIC	MutS-MutL in clamp state (kinked clamp domain) 分子名称: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ... 著者 Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. 登録日 2020-09-26 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
7AIB	MutS-MutL in clamp state 分子名称: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ... 著者 Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. 登録日 2020-09-26 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
7AI5	MutS in Scanning state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*AP*AP*TP*TP*CP*GP*CP*CP*CP*TP*AP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*TP*AP*GP*GP*GP*CP*GP*AP*AP*TP*TP*GP*GP*GP*TP*AP*CP*CP*G)-3'), ... 著者 Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. 登録日 2020-09-26 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
2O8C	human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair 分子名称: 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*(6OG)P*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. 登録日 2006-12-12 公開日 2007-06-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
2O8E	human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only 分子名称: 5'-D(*CP*CP*TP*AP*GP*CP*CP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*GP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. 登録日 2006-12-12 公開日 2007-06-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
2O8F	human MutSalpha (MSH2/MSH6) bound to DNA with a single base T insert 分子名称: 5'-D(*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*CP*GP*TP*C)-3', 5'-D(*GP*AP*CP*GP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. 登録日 2006-12-12 公開日 2007-06-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
2O8B	human MutSalpha (MSH2/MSH6) bound to ADP and a G T mispair 分子名称: 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. 登録日 2006-12-12 公開日 2007-06-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
2O8D	human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair 分子名称: 5'-D(*CP*CP*TP*AP*GP*CP*GP*(DU)P*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S. 登録日 2006-12-12 公開日 2007-06-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Human MutSalpha DNA Lesion Recognition Complex. Mol.Cell, 26, 2007
1OH8	THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN UNPAIRED THYMIDINE 分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP* TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*CP*TP*TP*GP*GP*CP* AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K. 登録日 2003-05-23 公開日 2003-08-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates Nucleic Acids Res., 31, 2003
1OH7	THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A G:G MISMATCH 分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*GP*TP*GP*GP *CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K. 登録日 2003-05-23 公開日 2003-08-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates Nucleic Acids Res., 31, 2003
1OH5	THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH A C:A MISMATCH 分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*CP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP *CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP *CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K. 登録日 2003-05-23 公開日 2003-08-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates Nucleic Acids Res., 31, 2003
1OH6	THE CRYSTAL STRUCTURE OF E. COLI MUTS BINDING TO DNA WITH AN A:A MISMATCH 分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*AP*GP *CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP* CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP *GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*AP*TP*GP*GP* CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Natrajan, G, Lamers, M.H, Enzlin, J.H, Winterwerp, H.H.K, Perrakis, A, Sixma, T.K. 登録日 2003-05-23 公開日 2003-08-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of E. Coli DNA Mismatch Repair Enzyme Muts in Complex with Different Mismatches: A Common Recognition Mode for Diverse Substrates Nucleic Acids Res., 31, 2003
8OM5	DNA-free open form of MutSbeta 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-31 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 DNA-free open form of MutSbeta To Be Published
8OMQ	DNA-unbound MutSbeta-ATP complex (straight clamp form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-31 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 DNA-unbound MutSbeta-ATP complex (straight clamp form) To Be Published
8OMO	DNA-unbound MutSbeta-ATP complex (bent clamp form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-31 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 DNA-unbound MutSbeta-ATP complex (bent clamp form) To Be Published
8OLX	MutSbeta bound to (CAG)2 DNA (canonical form) 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein Msh2, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-30 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 MutSbeta bound to (CAG)2 DNA (canonical form) To Be Published
8OMA	MutSbeta bound to 61bp homoduplex DNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-31 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 MutSbeta bound to 61bp homoduplex DNA To Be Published
8OM9	MutSbeta bound to (CAG)2 DNA (open form) 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... 著者 Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. 登録日 2023-03-31 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 MutSbeta bound to (CAG)2 DNA (open form) To Be Published
1NG9	E.coli MutS R697A: an ATPase-asymmetry mutant 分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP*GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... 著者 Lamers, M.H, Winterwerp, H.H.K, Sixma, T.K. 登録日 2002-12-17 公開日 2003-02-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The alternating ATPase domains of MutS control DNA mismatch repair Embo J., 22, 2003
1NNE	Crystal Structure of the MutS-ADPBeF3-DNA complex 分子名称: 1,2-ETHANEDIOL, 5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(P*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3', ... 著者 Alani, E, Lee, J.Y, Schofield, M.J, Kijas, A.W, Hsieh, P, Yang, W. 登録日 2003-01-13 公開日 2003-05-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair J.Biol.Chem., 278, 2003

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