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4YE9
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The crystal structure of the G45V mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE8
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The crystal structure of the Y57H mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
5BNZ
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Crystal structure of Glutamine-tRNA ligase /Glutaminyl-tRNA synthetase (GlnRS) from Pseudomonas aeruginosa
分子名称: CHLORIDE ION, Glutamine--tRNA ligase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-05-26
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Glutamine-tRNA ligase /Glutaminyl-tRNA synthetase (GlnRS) from Pseudomonas aeruginosa
to be published
3AFH
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Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with a glutamyl-AMP analog
分子名称: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE
著者Ito, T, Yokoyama, S.
登録日2010-03-01
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima
Acta Crystallogr.,Sect.D, 66, 2010
3AII
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Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ...
著者Nureki, O, Ishitani, R.
登録日2010-05-14
公開日2010-08-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation
Nucleic Acids Res., 2010
3AKZ
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Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with tRNAGln and a glutamyl-AMP analog
分子名称: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, tRNAGln
著者Ito, T, Yokoyama, S.
登録日2010-07-19
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.
Nature, 467, 2010
3AL0
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Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.
分子名称: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit A, Glutamyl-tRNA(Gln) amidotransferase subunit C,Linker,Glutamate--tRNA ligase 2, ...
著者Ito, T, Yokoyama, S.
登録日2010-07-19
公開日2010-09-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.368 Å)
主引用文献Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.
Nature, 467, 2010
1J09
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Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP and Glu
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTAMIC ACID, Glutamyl-tRNA synthetase, ...
著者Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-11-12
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
1N75
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Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION
著者Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-11-12
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
1N78
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Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP.
分子名称: GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ...
著者Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-11-13
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
1N77
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Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ...
著者Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-11-13
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
4G6Z
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Crystal structure of a glutamyl-tRNA synthetase GluRS from Burkholderia thailandensis bound to L-glutamate
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLUTAMIC ACID, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-07-19
公開日2012-08-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
Sci Rep, 7, 2017
4GRI
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Crystal structure of a glutamyl-tRNA synthetase GluRS from Borrelia burgdorferi bound to glutamic acid and zinc
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate--tRNA ligase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-08-24
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
Sci Rep, 7, 2017
4H3S
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The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, BROMIDE ION, ...
著者Snell, E.H, Grant, T.D.
登録日2012-09-14
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Structure of Yeast Glutaminyl-tRNA Synthetase and Modeling of Its Interaction with tRNA.
J.Mol.Biol., 425, 2013
2CV0
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BU of 2cv0 by Molmil
Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and L-glutamate
分子名称: GLUTAMIC ACID, MAGNESIUM ION, glutamyl-tRNA synthetase, ...
著者Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-31
公開日2006-09-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
2CV2
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Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and an enzyme inhibitor, Glu-AMS
分子名称: CHLORIDE ION, MAGNESIUM ION, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ...
著者Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-31
公開日2006-09-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
2CV1
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Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex
分子名称: (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-31
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex
To be Published
2CUZ
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Glutamyl-tRNA synthetase from Thermus thermophilus in complex with L-glutamate
分子名称: GLUTAMIC ACID, Glutamyl-tRNA synthetase
著者Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-31
公開日2006-09-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
2CFO
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Non-Discriminating Glutamyl-tRNA Synthetase from Thermosynechococcus elongatus in Complex with Glu
分子名称: GLUTAMIC ACID, GLUTAMYL-TRNA SYNTHETASE
著者Schulze, J.O, Nickel, D, Schubert, W.-D, Jahn, D, Heinz, D.W.
登録日2006-02-22
公開日2006-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of a Non-Discriminating Glutamyl- tRNA Synthetase.
J.Mol.Biol., 361, 2006
4JXX
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Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG) and ATP from novel cryostabilization conditions
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-03-28
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JXZ
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Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-03-28
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JYZ
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Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (72-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-04-01
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
2DXI
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2.2 A crystal structure of glutamyl-tRNA synthetase from Thermus thermophilus complexed with tRNA(Glu), ATP, and L-glutamol
分子名称: (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-28
公開日2006-10-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
1O0C
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CRYSTAL STRUCTURE OF L-GLUTAMATE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE
分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMIC ACID, Glutaminyl tRNA, ...
著者Bullock, T.L, Perona, J.J.
登録日2003-02-20
公開日2003-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants
J.Mol.Biol., 328, 2003
1NYL
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Unliganded glutaminyl-tRNA synthetase
分子名称: Glutaminyl-tRNA synthetase
著者Sherlin, L.D, Perona, J.P.
登録日2003-02-12
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献tRNA-Dependent Active Site Assembly in a Class I Aminoacyl-tRNA Synthetase.
Structure, 11, 2003

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