PDB: 121 件ウェブページステータス検索Chemie searchBIRD

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2R3V	The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism 分子名称: Mevalonate kinase 著者 Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. 登録日 2007-08-30 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
1PIE	Crystal Structure of Lactococcus lactis Galactokinase Complexed with Galactose 分子名称: Galactokinase, PHOSPHATE ION, alpha-D-galactopyranose 著者 Thoden, J.B, Holden, H.M. 登録日 2003-05-30 公開日 2003-09-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular Structure of Galactokinase J.Biol.Chem., 278, 2003
5GME	Crystal structure of Sulfolobus solfataricus Diphosphomevalonate decarboxylase in complex with ADP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Unno, H, Hemmi, H, Hattori, A. 登録日 2016-07-13 公開日 2016-12-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase J. Biol. Chem., 292, 2017
3F0N	Mus Musculus Mevalonate Pyrophosphate Decarboxylase 分子名称: MEVALONATE PYROPHOSPHATE DECARBOXYLASE, PHOSPHATE ION 著者 Walker, J.R, Davis, T, Vesterberg, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-10-25 公開日 2008-11-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Mus Musculus Mevalonate Pyrophosphate Decarboxylase To be Published
4Z7C	Diphosphomevalonate decarboxylase from the Sulfolobus solfataricus, space group h32 分子名称: Diphosphomevalonate decarboxylase, GLYCEROL, PHOSPHATE ION, ... 著者 Unno, H, Hattori, A, Hemmi, H. 登録日 2015-04-07 公開日 2015-09-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus J.Bacteriol., 197, 2015
3D4J	Crystal structure of Human mevalonate diphosphate decarboxylase 分子名称: Diphosphomevalonate decarboxylase, SULFATE ION 著者 Voynova, N.E, Fu, Z, Battaile, K, Herdendorf, T.J, Kim, J.-J.P, Miziorko, H.M. 登録日 2008-05-14 公開日 2008-12-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. Arch.Biochem.Biophys., 480, 2008
8TFO	Structure of MKvar 分子名称: (R)-MEVALONATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Peat, T.S, Newman, J, Esquirol, L, Nebl, T, Scott, C, Vickers, C, Sainsbury, F. 登録日 2023-07-11 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Characterization of novel mevalonate kinases from the tardigrade Ramazzottius varieornatus and the psychrophilic archaeon Methanococcoides burtonii. Acta Crystallogr D Struct Biol, 80, 2024
8TEB	Structure of MKbur 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Peat, T.S, Newman, J, Esquirol, L, Nebl, T, Scott, C, Vickers, C, Sainsbury, F. 登録日 2023-07-06 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of novel mevalonate kinases from the tardigrade Ramazzottius varieornatus and the psychrophilic archaeon Methanococcoides burtonii. Acta Crystallogr D Struct Biol, 80, 2024
3V2U	Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Galactose/lactose metabolism regulatory protein GAL80, ... 著者 Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. 登録日 2011-12-12 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes Dev., 26, 2012
4Z7Y	diphosphomevalonate decarboxylase from the Sulfolobus solfataricus, space group P21 分子名称: Diphosphomevalonate decarboxylase, SULFATE ION 著者 Hattori, A, Unno, H, Hemmi, H. 登録日 2015-04-08 公開日 2015-09-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus J.Bacteriol., 197, 2015
3V5R	Crystal structure of the unliganded form of Gal3p 分子名称: Protein GAL3, SULFATE ION 著者 Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. 登録日 2011-12-16 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes Dev., 26, 2012
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2A2D	X-ray structure of human n-acetyl galactosamine kinase complexed with Mn-AMPPNP and n-acetyl glactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, N-acetylgalactosamine kinase, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
4UTG	Burkholderia pseudomallei heptokinase WcbL,AMPPNP (ATP analogue) complex. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-21 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
4UT4	Burkholderia pseudomallei heptokinase WcbL, D-mannose complex. 分子名称: CHLORIDE ION, PUTATIVE SUGAR KINASE, alpha-D-mannopyranose 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-18 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
4USM	WcbL complex with glycerol bound to sugar site 分子名称: CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-10 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
1UEK	Crystal structure of 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase 分子名称: 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase 著者 Wada, T, Kuramitsu, S, Yokoyama, S, Tame, J.R.H, Park, S.Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-05-17 公開日 2003-06-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis. J.Biol.Chem., 278, 2003
1K47	Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK) 分子名称: phosphomevalonate kinase 著者 Romanowski, M.J, Bonanno, J.B, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2001-10-05 公開日 2002-05-08 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily. Proteins, 47, 2002
1KKH	Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase 分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase 著者 Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C. 登録日 2001-12-08 公開日 2002-03-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily. J.Biol.Chem., 277, 2002
1KVK	The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase 著者 Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J. 登録日 2002-01-26 公開日 2002-03-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease J.Biol.Chem., 277, 2002
6TEP	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
6TER	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with Galactose 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
6TEQ	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-alpha-D-galactopyranose, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
1S4E	Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium 分子名称: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... 著者 Hartley, A, Glynn, S.E, Barynin, V, Baker, P.J, Sedelnikova, S.E, Verhees, C, de Geus, D, van der Oost, J, Timson, D.J, Reece, R.J, Rice, D.W. 登録日 2004-01-16 公開日 2004-04-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase J.Mol.Biol., 337, 2004
1VIS	Crystal structure of mevalonate kinase 分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate kinase 著者 Structural GenomiX 登録日 2003-12-01 公開日 2003-12-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005

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