1EVT
 
 | | CRYSTAL STRUCTURE OF FGF1 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 1 (FGFR1) | | 分子名称: | PROTEIN (FIBROBLAST GROWTH FACTOR 1), PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 1), SULFATE ION | | 著者 | Plotnikov, A.N, Hubbard, S.R, Schlessinger, J, Mohammadi, M. | | 登録日 | 2000-04-20 | | 公開日 | 2000-05-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101, 2000
|
|
1FMM
 | | SOLUTION STRUCTURE OF NFGF-1 | | 分子名称: | ACIDIC FIBROBLAST GROWTH FACTOR | | 著者 | Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. | | 登録日 | 2000-08-18 | | 公開日 | 2001-08-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens.
J.Biol.Chem., 277, 2002
|
|
1FQ9
 | | CRYSTAL STRUCTURE OF A TERNARY FGF2-FGFR1-HEPARIN COMPLEX | | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, FIBROBLAST GROWTH FACTOR 2, ... | | 著者 | Schlessinger, J, Plotnikov, A.N, Ibrahimi, O.A, Eliseenkova, A.V, Yeh, B.K, Yayon, A, Linhardt, R.J, Mohammadi, M. | | 登録日 | 2000-09-04 | | 公開日 | 2000-09-27 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
Mol.Cell, 6, 2000
|
|
1G82
 | | STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FIBROBLAST GROWTH FACTOR 9, ... | | 著者 | Hecht, H.J, Adar, R, Hofmann, B, Bogin, O, Weich, H, Yayon, A. | | 登録日 | 2000-11-16 | | 公開日 | 2001-03-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces.
Acta Crystallogr.,Sect.D, 57, 2001
|
|
1IHK
 | | CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 (FGF9) | | 分子名称: | GLIA-ACTIVATING FACTOR, PHOSPHATE ION | | 著者 | Plotnikov, A.N, Eliseenkova, A.V, Ibrahimi, O.A, Lemmon, M.A, Mohammadi, M. | | 登録日 | 2001-04-19 | | 公開日 | 2001-05-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition.
J.Biol.Chem., 276, 2001
|
|
1II4
 | | CRYSTAL STRUCTURE OF SER252TRP APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2 | | 分子名称: | FIBROBLAST GROWTH FACTOR RECEPTOR 2, HEPARIN-BINDING GROWTH FACTOR 2 | | 著者 | Ibrahimi, O.A, Eliseenkova, A.V, Plotnikov, A.N, Ornitz, D.M, Mohammadi, M. | | 登録日 | 2001-04-20 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1IIL
 | | CRYSTAL STRUCTURE OF PRO253ARG APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2 | | 分子名称: | FIBROBLAST GROWTH FACTOR RECEPTOR 2, HEPARIN-BINDING GROWTH FACTOR 2 | | 著者 | Ibrahimi, O.A, Eliseenkova, A.V, Plotnikov, A.N, Ornitz, D.M, Mohammadi, M. | | 登録日 | 2001-04-23 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1IJT
 | | Crystal Structure of Fibroblast Growth Factor 4 (FGF4) | | 分子名称: | SULFATE ION, fibroblast growth factor 4 | | 著者 | Bellosta, P, Plotnikov, A.N, Eliseenkova, A.V, Basilico, C, Mohammadi, M. | | 登録日 | 2001-04-29 | | 公開日 | 2001-08-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis.
Mol.Cell.Biol., 21, 2001
|
|
1JQZ
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. | | 分子名称: | FORMIC ACID, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-09 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JT4
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L) | | 分子名称: | FORMIC ACID, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JT7
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L) | | 分子名称: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JT5
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L) | | 分子名称: | SULFATE ION, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JTC
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F) | | 分子名称: | FORMIC ACID, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JT3
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) | | 分子名称: | SULFATE ION, acidic fibroblast growth factor | | 著者 | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
|
|
1JY0
 | |
1K5U
 | |
1K5V
 | |
1M16
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V). | | 分子名称: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | | 著者 | Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M. | | 登録日 | 2002-06-17 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
|
|
1NUN
 | | Crystal Structure Analysis of the FGF10-FGFR2b Complex | | 分子名称: | Fibroblast growth factor-10, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... | | 著者 | Yeh, B.K, Igarashi, M, Eliseenkova, A.V, Plotnikov, A.N, Sher, I, Ron, D, Aaronson, S.A, Mohammadi, M. | | 登録日 | 2003-01-31 | | 公開日 | 2003-02-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis by which alternative splicing confers
specificity in fibroblast growth factor receptors.
Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1NZK
 | | Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor | | 分子名称: | Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION | | 著者 | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | | 登録日 | 2003-02-18 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
|
|
1HKN
 | | A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate | | 分子名称: | 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 | | 著者 | Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2003-03-10 | | 公開日 | 2004-03-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
|
|
1P63
 | | Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) | | 分子名称: | ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION | | 著者 | Brych, S.R, Kim, J, Logan, T.M, Blaber, M. | | 登録日 | 2003-04-28 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Accommodation of a highly symmetric core within a symmetric protein
superfold
Protein Sci., 12, 2003
|
|
1PWA
 | | Crystal structure of Fibroblast Growth Factor 19 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | | 著者 | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | | 登録日 | 2003-07-01 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
|
|
1PZZ
 | | Crystal structure of FGF-1, V51N mutant | | 分子名称: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | 著者 | Kim, J, Blaber, M. | | 登録日 | 2003-07-14 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
|
|
1Q04
 | | Crystal structure of FGF-1, S50E/V51N | | 分子名称: | FORMIC ACID, Heparin-binding growth factor 1 | | 著者 | Kim, J, Blaber, M. | | 登録日 | 2003-07-15 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
|
|
