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9C0B
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E.coli GroEL + PBZ1587 inhibitor
分子名称: 60 kDa chaperonin, N-(2-{4-[4-(aminomethyl)benzene-1-sulfonamido]phenyl}-1,3-benzoxazol-5-yl)-5-chlorothiophene-2-sulfonamide
著者Watson, E.R, Lander, G.C.
登録日2024-05-25
公開日2024-08-07
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target.
J.Am.Chem.Soc., 146, 2024
6TMU
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Crystal structure of the chaperonin gp146 from the bacteriophage EL 2 (Pseudomonas aeruginosa) in presence of ATP-BeFx, crystal form II
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Bracher, A, Paul, S.S, Wang, H, Wischnewski, N, Hartl, F.U, Hayer-Hartl, M.
登録日2019-12-05
公開日2020-04-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献Structure and conformational cycle of a bacteriophage-encoded chaperonin.
Plos One, 15, 2020
6TMX
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Structure of the chaperonin gp146 from the bacteriophage EL (Pseudomonas aeruginosa) in complex with ATPgammaS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, POTASSIUM ION, ...
著者Bracher, A, Wang, H, Paul, S.S, Wischnewski, N, Hartl, F.U, Hayer-Hartl, M.
登録日2019-12-05
公開日2020-04-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structure and conformational cycle of a bacteriophage-encoded chaperonin.
Plos One, 15, 2020
9C0D
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E.Faecium GroEL
分子名称: Chaperonin GroEL
著者Watson, E.R, Lander, G.C.
登録日2024-05-25
公開日2024-08-07
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target.
J.Am.Chem.Soc., 146, 2024
9C0C
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BU of 9c0c by Molmil
E.coli GroEL apoenzyme
分子名称: 60 kDa chaperonin
著者Watson, E.R, Lander, G.C.
登録日2024-05-25
公開日2024-08-07
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target.
J.Am.Chem.Soc., 146, 2024
4XCG
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Crystal structure of a hexadecameric TF55 complex from S. solfataricus, crystal form I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Thermosome subunit alpha, Thermosome subunit beta
著者Stewart, A.G, Smits, C, Chaston, J.J, Stock, D.
登録日2014-12-18
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.737 Å)
主引用文献Structural and Functional Insights into the Evolution and Stress Adaptation of Type II Chaperonins.
Structure, 24, 2016
6TMW
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Structure of the chaperonin gp146 from the bacteriophage EL (Pseudomonas aeruginosa) in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative GroEL-like chaperonine protein
著者Bracher, A, Wang, H, Paul, S.S, Wischnewski, N, Hartl, F.U, Hayer-Hartl, M.
登録日2019-12-05
公開日2020-04-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.91 Å)
主引用文献Structure and conformational cycle of a bacteriophage-encoded chaperonin.
Plos One, 15, 2020
4XCD
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Crystal structure of an octadecameric TF55 complex from S. solfataricus
分子名称: ADENOSINE-5'-DIPHOSPHATE, Thermosome subunit beta
著者Chaston, J.J, Stewart, A.G, Smits, C, Stock, D.
登録日2014-12-17
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献Structural and Functional Insights into the Evolution and Stress Adaptation of Type II Chaperonins.
Structure, 24, 2016
4WSC
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Crystal structure of a GroELK105A mutant
分子名称: 60 kDa chaperonin
著者Lorimer, G.H, Ye, X, Fei, X, Yang, D, Corsepius, N, LaRonde, N.A.
登録日2014-10-26
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal structure of a GroELK105A mutant
To Be Published
4XCI
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Crystal structure of a hexadecameric TF55 complex from S. solfataricus, crystal form II
分子名称: Thermosome subunit alpha, Thermosome subunit beta
著者Stewart, A.G, Chaston, J.J, Smits, C, Stock, D.
登録日2014-12-18
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.0023 Å)
主引用文献Structural and Functional Insights into the Evolution and Stress Adaptation of Type II Chaperonins.
Structure, 24, 2016
3C9V
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BU of 3c9v by Molmil
C7 Symmetrized Structure of Unliganded GroEL at 4.7 Angstrom Resolution from CryoEM
分子名称: 60 kDa chaperonin
著者Ludtke, S.J, Baker, M.L, Chen, D.H, Song, J.L, Chuang, D, Chiu, W.
登録日2008-02-18
公開日2008-09-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献De Novo Backbone Trace of GroEL from Single Particle Electron Cryomicroscopy.
Structure, 16, 2008
3CAU
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BU of 3cau by Molmil
D7 symmetrized structure of unliganded GroEL at 4.2 Angstrom resolution by cryoEM
分子名称: 60 kDa chaperonin
著者Ludtke, S.J, Baker, M.L, Chen, D.H, Song, J.L, Chuang, D, Chiu, W.
登録日2008-02-20
公開日2008-09-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献De Novo Backbone Trace of GroEL from Single Particle Electron Cryomicroscopy.
Structure, 16, 2008
4WGL
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Crystal structure of a GroEL D83A/R197A double mutant
分子名称: 60 kDa chaperonin
著者Yang, D, Fei, X, LaRonde, N.A, Beckett, D, Lund, P.A, Lorimer, G.H.
登録日2014-09-19
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Crystal structure of a GroEL D83A/R197A double mutant
To Be Published
1SRV
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BU of 1srv by Molmil
THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336
分子名称: PROTEIN (GROEL (HSP60 CLASS))
著者Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A.
登録日1999-03-02
公開日1999-03-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Taking MAD to the extreme: ultrafast protein structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
3AQ1
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Open state monomer of a group II chaperonin from methanococcoides burtonii
分子名称: Thermosome subunit
著者Harrop, S.J, Pilak, O, Siddiqui, K.S, De Francisci, D, Burg, D, Williams, T.J, Cavicchioli, R, Curmi, P.M.
登録日2010-10-24
公開日2011-09-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.746 Å)
主引用文献Chaperonins from an Antarctic archaeon are predominantly monomeric: crystal structure of an open state monomer.
ENVIRON.MICROBIOL., 13, 2011
1XCK
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BU of 1xck by Molmil
Crystal structure of apo GroEL
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 60 kDa chaperonin, DI(HYDROXYETHYL)ETHER, ...
著者Bartolucci, C, Lamba, D, Grazulis, S, Manakova, E, Heumann, H.
登録日2004-09-02
公開日2005-10-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Crystal structure of wild-type chaperonin GroEL
J.Mol.Biol., 354, 2005
1KP8
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BU of 1kp8 by Molmil
Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, POTASSIUM ION, ...
著者Wang, J.
登録日2001-12-30
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution
J.Mol.Biol., 327, 2003
5W74
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BU of 5w74 by Molmil
Crystal Structure of the Group II Chaperonin from Methanococcus Maripaludis D386ADeltaLid Mutant in the Open, ADP-Bound State
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperonin, MAGNESIUM ION
著者Dalton, K.M, Lopez, T, Liu, C, Ralston, C.Y, Pereira, J.H, Chartron, J.W, McAndrew, R.P, Douglas, N.R, Adams, P.D, Pande, V.S, Frydman, J.
登録日2017-06-19
公開日2018-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献The Conformational Cycle of the Group II Chaperonin Termini
To Be Published
4V81
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The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, SULFATE ION, ...
著者Dekker, C, Roe, S.M, McCormack, E.A, Beuron, F, Pearl, L.H, Willison, K.R.
登録日2010-10-17
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins.
Embo J., 30, 2011
7NVL
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BU of 7nvl by Molmil
Human TRiC complex in closed state with nanobody bound (Consensus Map)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC)
登録日2021-03-15
公開日2022-03-02
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
7NVO
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Human TRiC complex in open state with nanobody bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W.
登録日2021-03-15
公開日2022-03-02
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
4V94
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Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J.
登録日2012-01-11
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Structure, 20, 2012
4V43
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Structural and mechanistic basis for allostery in the bacterial chaperonin GroEL
分子名称: GROEL PROTEIN
著者Wang, J.
登録日2002-01-02
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献A GroEL/GroES complex structure revisited: the structure-based mechanism of ATP hydrolysis
To be Published
3RUW
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Crystal structure of Cpn-rls in complex with ADP-AlFx from Methanococcus maripaludis
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Chaperonin, ...
著者Pereira, J.H, Ralston, C.Y, Douglas, N.R, Kumar, R, McAndrew, R.P, Knee, K.M, King, J.A, Frydman, J, Adams, P.D.
登録日2011-05-05
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Mechanism of nucleotide sensing in group II chaperonins.
Embo J., 31, 2012
5W79
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Crystal Structure of the Group II Chaperonin from Methanococcus Maripaludis, Cysteine-less mutant in the Apo State
分子名称: Chaperonin, SULFATE ION
著者Dalton, K.M, Lopez, T, Liu, C, Ralston, C.Y, Pereira, J.H, Chartron, J.W, McAndrew, R.P, Douglas, N.R, Adams, P.D, Pande, V.S, Frydman, J.
登録日2017-06-19
公開日2018-06-20
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (3.122 Å)
主引用文献The Conformational Cycle of the Group II Chaperonin Termini
To Be Published

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