Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6TZE
DownloadVisualize
BU of 6tze by Molmil
Human CstF-64 RRM mutant - D50A
分子名称: Cleavage stimulation factor subunit 2
著者Latham, M.P, Masoumzadeh, E.
登録日2019-08-12
公開日2020-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans.
Nucleic Acids Res., 48, 2020
7S3A
DownloadVisualize
BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
著者Jenkins, J.L, Henderson, S, Kielkopf, C.L.
登録日2021-09-05
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3B
DownloadVisualize
BU of 7s3b by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
著者Jenkins, J.L, Henderson, S, Kielkopf, C.L.
登録日2021-09-05
公開日2022-05-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3C
DownloadVisualize
BU of 7s3c by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
著者Glasser, E, Jenkins, J.L, Kielkopf, C.L.
登録日2021-09-05
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
5ZUH
DownloadVisualize
BU of 5zuh by Molmil
Solution structure of RRM domain of La protein from Trypanosoma brucei
分子名称: RNA binding protein La-like protein
著者Shan, F.Z.
登録日2018-05-07
公開日2019-05-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis.
Febs J., 286, 2019
1CVJ
DownloadVisualize
BU of 1cvj by Molmil
X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA
分子名称: 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', ADENOSINE MONOPHOSPHATE, POLYADENYLATE BINDING PROTEIN 1
著者Deo, R.C, Bonanno, J.B, Sonenberg, N, Burley, S.K.
登録日1999-08-23
公開日1999-10-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition of polyadenylate RNA by the poly(A)-binding protein.
Cell(Cambridge,Mass.), 98, 1999
1D9A
DownloadVisualize
BU of 1d9a by Molmil
SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN (RBD2) OF HU ANTIGEN C (HUC)
分子名称: HU ANTIGEN C
著者Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日1999-10-26
公開日2000-04-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1D8Z
DownloadVisualize
BU of 1d8z by Molmil
SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN (RBD1) OF HU ANTIGEN C (HUC)
分子名称: HU ANTIGEN C
著者Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日1999-10-26
公開日2000-04-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1DZ5
DownloadVisualize
BU of 1dz5 by Molmil
The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
分子名称: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
著者Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G.
登録日2000-02-16
公開日2000-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
1DRZ
DownloadVisualize
BU of 1drz by Molmil
U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
分子名称: MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ...
著者Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A.
登録日1998-09-01
公開日1999-02-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
8RZV
DownloadVisualize
BU of 8rzv by Molmil
Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
著者Dunnett, L, Prischi, F.
登録日2024-02-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
To Be Published
7LHX
DownloadVisualize
BU of 7lhx by Molmil
Human U1A protein with F37M and F77M mutations for improved phasing
分子名称: ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ...
著者Jenkins, J.L, Lippa, G.M, Wedekind, J.E.
登録日2021-01-26
公開日2021-03-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing
Crystals, 11, 2021
2A3J
DownloadVisualize
BU of 2a3j by Molmil
Structure of URNdesign, a complete computational redesign of human U1A protein
分子名称: U1 small nuclear ribonucleoprotein A
著者Varani, G, Dobson, N, Dantas, G, Baker, D.
登録日2005-06-24
公開日2006-06-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein
Structure, 14, 2006
2AYM
DownloadVisualize
BU of 2aym by Molmil
Solution Structure of Drosophila melanogaster SNF RBD2
分子名称: U1 small nuclear ribonucleoprotein A
著者Cui, G, Li, C, Jin, C, Xia, B.
登録日2005-09-07
公開日2007-02-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of Drosophila melanogaster SNF RBD2
To be published
2B0G
DownloadVisualize
BU of 2b0g by Molmil
Solution Structure of Drosophila melanogaster SNF RBD2
分子名称: U1 small nuclear ribonucleoprotein A
著者Cui, G, Li, C, Jin, C, Xia, B.
登録日2005-09-14
公開日2006-12-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of Drosophila melanogaster SNF RBD2
TO BE PUBLISHED
1ZZN
DownloadVisualize
BU of 1zzn by Molmil
Crystal structure of a group I intron/two exon complex that includes all catalytic metal ion ligands.
分子名称: 197-MER, 5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*AP*GP*AP*CP*GP*GP*CP*C)-3', 5'-R(*CP*AP*(5MU))-3', ...
著者Stahley, M.R, Strobel, S.A.
登録日2005-06-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural evidence for a two-metal-ion mechanism of group I intron splicing.
Science, 309, 2005
5SZW
DownloadVisualize
BU of 5szw by Molmil
NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR
分子名称: ELAV-like protein 1
著者Lixa, C, Mujo, A, Jendiroba, K.A, Almeida, F.C.L, Lima, L.M.T.R, Pinheiro, A.S.
登録日2016-08-15
公開日2017-09-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
J. Biomol. NMR, 72, 2018
1L3K
DownloadVisualize
BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
分子名称: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
著者Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
登録日2002-02-27
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
1M5O
DownloadVisualize
BU of 1m5o by Molmil
Transition State Stabilization by a Catalytic RNA
分子名称: CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ...
著者Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R.
登録日2002-07-09
公開日2002-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Transition state stabilization by a catalytic RNA
Science, 298, 2002
5T9P
DownloadVisualize
BU of 5t9p by Molmil
Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate
分子名称: CHLORIDE ION, Ribosome biogenesis protein 15, SULFATE ION
著者Zhang, J, Gonzalez, E.L, Hall, M.T.T.
登録日2016-09-09
公開日2016-11-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate.
Nucleic Acids Res., 45, 2017
1M5P
DownloadVisualize
BU of 1m5p by Molmil
Transition State Stabilization by a Catalytic RNA
分子名称: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ...
著者Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R.
登録日2002-07-09
公開日2002-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Transition state stabilization by a catalytic RNA
Science, 298, 2002
1JMT
DownloadVisualize
BU of 1jmt by Molmil
X-ray Structure of a Core U2AF65/U2AF35 Heterodimer
分子名称: HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K.
登録日2001-07-19
公開日2001-09-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Cell(Cambridge,Mass.), 106, 2001
5TBX
DownloadVisualize
BU of 5tbx by Molmil
hnRNP A18 RNA Recognition Motif
分子名称: ACETATE ION, Cold-inducible RNA-binding protein, NICKEL (II) ION
著者Coburn, K.M, Melville, Z, Aligholizadeh, E, Roth, B.M, Varney, K.M, Weber, D.J.
登録日2016-09-13
公開日2017-04-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.767 Å)
主引用文献Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5TKZ
DownloadVisualize
BU of 5tkz by Molmil
MEC-8 N-terminal RRM bound to tandem GCAC ligand
分子名称: DNA (5'-D(*AP*GP*CP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*TP*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
著者Soufari, H, Mackereth, C.D.
登録日2016-10-10
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.529 Å)
主引用文献Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5UZG
DownloadVisualize
BU of 5uzg by Molmil
Crystal structure of Glorund qRRM1 domain
分子名称: AT27789p, GLYCEROL, SULFATE ION
著者Teramoto, T, Hall, T.M.T.
登録日2017-02-26
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.541 Å)
主引用文献The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition.
Cell Rep, 19, 2017

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon