PDB: 1001 件ウェブページステータス検索Chemie searchBIRD

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7YPZ	Zafirlukast in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-08-05 公開日 2023-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
2WG5	Proteasome-Activating Nucleotidase (PAN) N-domain (57-134) from Archaeoglobus fulgidus fused to GCN4 分子名称: GENERAL CONTROL PROTEIN GCN4, PROTEASOME-ACTIVATING NUCLEOTIDASE 著者 Hartmann, M.D, Djuranovic, S, Ursinus, A, Zeth, K, Lupas, A.N. 登録日 2009-04-15 公開日 2009-04-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal Atpases. Mol.Cell, 34, 2009
5UWU	Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GLYCEROL, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWQ	Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.278 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWJ	Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.221 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWR	Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1 分子名称: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWP	Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.054 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWO	Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.347 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWH	Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWT	Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.342 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWS	Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWW	Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1 分子名称: Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
5UWI	Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.143 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017
6DJL	Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A 分子名称: Ras-related protein Rab-11A, SH3 domain-binding protein 5 著者 Burke, J.E, Jenkins, M.L, Boulanger, M.J. 登録日 2018-05-25 公開日 2018-09-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.10001159 Å) 主引用文献 Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5. Nat Commun, 9, 2018
2PT7	Crystal structure of Cag VirB11 (HP0525) and an inhibitory protein (HP1451) 分子名称: Cag-alfa, Hypothetical protein 著者 Hare, S, Fischer, W, Williams, R, Terradot, L, Bayliss, R, Haas, R, Waksman, G. 登録日 2007-05-08 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase. Embo J., 26, 2007
8VOF	GI targeted CpPI4K inhibitor 分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2 of Phosphatidylinositol 4-kinase beta,Isoform 2 of Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Knapp, M.S, Cuellar, C, Mamo, M. 登録日 2024-01-15 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Rational design of GI targeted parasiticidal agent to treat pediatric enteric cryptosporidiosis To Be Published
6X2M	Crystal Structure of unliganded CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
7Q3H	Pentameric ligand-gated ion channel, DeCLIC at pH 7 with 10 mM EDTA 分子名称: Neur_chan_LBD domain-containing protein 著者 Lycksell, M, Rovsnik, U, Hanke, A, Howard, R.J, Lindahl, E. 登録日 2021-10-27 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7Q3G	Pentameric ligand-gated ion channel, DeCLIC at pH 7 with 10 mM Ca2+ 分子名称: CALCIUM ION, Neur_chan_LBD domain-containing protein 著者 Licksell, M, Rovsnik, U, Hanke, A, Howard, R.J, Lindahl, E. 登録日 2021-10-27 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel. Proc.Natl.Acad.Sci.USA, 119, 2022
6YU1	CLK3 bound with beta-carboline KH-CARB13 (Cpd 3) 分子名称: (4~{S})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile, 1,2-ETHANEDIOL, Dual specificity protein kinase CLK3, ... 著者 Schroeder, M, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-04-25 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. J.Med.Chem., 63, 2020
1QF2	THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-GLY-(5-PHENYLPROLINE). PARAMETERS FOR ZN-MONODENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, PROTEIN (THERMOLYSIN), ... 著者 Gaucher, J.-F, Selkti, M, Tiraboschi, G, Prange, T, Roques, B.P, Tomas, A, Fournie-Zaluski, M.C. 登録日 1999-04-06 公開日 1999-12-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases. Biochemistry, 38, 1999
9FTJ	Closed and disordered conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA 分子名称: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein 著者 Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. 登録日 2024-06-24 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel To Be Published
6BGE	HELICOBACTER PYLORI ATPASE, HP0525, IN COMPLEX WITH 1G2 COMPOUND 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[(pyridin-2-yl)oxy]benzoic acid, GLYCEROL, ... 著者 Arya, T, Casu, B, Baron, C. 登録日 2017-10-27 公開日 2018-10-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 CagAlpha in complex with hexamer inhibitor To Be Published
9FTI	Open conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA 分子名称: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein 著者 Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. 登録日 2024-06-24 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel To Be Published
9FTG	Closed conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10 mM Ca2+ 分子名称: CALCIUM ION, Neurotransmitter-gated ion-channel ligand-binding domain-containing protein 著者 Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. 登録日 2024-06-24 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel To Be Published

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