5N65
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![BU of 5n65 by Molmil](/molmil-images/mine/5n65) | Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9h | 分子名称: | 2-phenyl-~{N}4-(2-thiophen-2-ylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 | 著者 | Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. | 登録日 | 2017-02-14 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
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5N64
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![BU of 5n64 by Molmil](/molmil-images/mine/5n64) | Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9g | 分子名称: | 2-phenyl-~{N}4-(thiophen-2-ylmethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 | 著者 | Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. | 登録日 | 2017-02-14 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
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3O7M
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![BU of 3o7m by Molmil](/molmil-images/mine/3o7m) | 1.98 Angstrom resolution crystal structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-2) from Bacillus anthracis str. 'Ames Ancestor' | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, Hypoxanthine phosphoribosyltransferase, ... | 著者 | Halavaty, A.S, Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-07-30 | 公開日 | 2010-09-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | 1.98 Angstrom resolution crystal structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-2) from Bacillus anthracis str. 'Ames Ancestor' TO BE PUBLISHED
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5MZ3
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![BU of 5mz3 by Molmil](/molmil-images/mine/5mz3) | P38 ALPHA MUTANT C162S IN COMPLEX WITH CMPD2 [N-(4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(trifluoromethyl)benzamide] | 分子名称: | Mitogen-activated protein kinase 14, ~{N}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide | 著者 | Cowan-Jacob, S.W, Scheufler, C. | 登録日 | 2017-01-30 | 公開日 | 2017-11-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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3O1N
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![BU of 3o1n by Molmil](/molmil-images/mine/3o1n) | 1.03 Angstrom Crystal Structure of Q236A Mutant Type I Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium | 分子名称: | 3-dehydroquinate dehydratase, CHLORIDE ION, MAGNESIUM ION | 著者 | Light, S.H, Minasov, G, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-07-21 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding. Biochemistry, 50, 2011
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3NQR
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![BU of 3nqr by Molmil](/molmil-images/mine/3nqr) | A putative CBS domain-containing protein from Salmonella typhimurium LT2 | 分子名称: | ADENOSINE MONOPHOSPHATE, Magnesium and cobalt efflux protein corC | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Shuvalova, L, Cui, H, Joachimiak, A, Anderson, F.W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-06-29 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A putative CBS domain-containing protein from Salmonella typhimurium LT2. To be Published
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5N66
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![BU of 5n66 by Molmil](/molmil-images/mine/5n66) | Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9j | 分子名称: | 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 14, ~{N}4-[[4-(cyclopropylmethyl)furan-2-yl]methyl]-2-phenyl-quinazoline-4,7-diamine | 著者 | Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. | 登録日 | 2017-02-14 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
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3NVT
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![BU of 3nvt by Molmil](/molmil-images/mine/3nvt) | 1.95 Angstrom crystal structure of a bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase (aroA) from Listeria monocytogenes EGD-e | 分子名称: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, ACETATE ION, MANGANESE (II) ION | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Shuvalova, L, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-07-08 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain. Protein Sci., 21, 2012
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3OEX
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![BU of 3oex by Molmil](/molmil-images/mine/3oex) | Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium with close loop conformation. | 分子名称: | 3-dehydroquinate dehydratase, CHLORIDE ION | 著者 | Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-13 | 公開日 | 2010-09-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding. Biochemistry, 50, 2011
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3OET
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![BU of 3oet by Molmil](/molmil-images/mine/3oet) | D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD | 分子名称: | Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Edwards, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-13 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD To be Published
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3OKF
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![BU of 3okf by Molmil](/molmil-images/mine/3okf) | 2.5 Angstrom Resolution Crystal Structure of 3-Dehydroquinate Synthase (aroB) from Vibrio cholerae | 分子名称: | 3-dehydroquinate synthase, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-24 | 公開日 | 2010-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 2.5 Angstrom Resolution Crystal Structure of 3-Dehydroquinate Synthase (aroB) from Vibrio cholerae. TO BE PUBLISHED
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3OYT
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![BU of 3oyt by Molmil](/molmil-images/mine/3oyt) | 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 | 分子名称: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase I, DI(HYDROXYETHYL)ETHER, ... | 著者 | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-23 | 公開日 | 2011-01-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 To be Published
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3OT5
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![BU of 3ot5 by Molmil](/molmil-images/mine/3ot5) | 2.2 Angstrom Resolution Crystal Structure of putative UDP-N-acetylglucosamine 2-epimerase from Listeria monocytogenes | 分子名称: | DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, UDP-N-acetylglucosamine 2-epimerase | 著者 | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-10 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | 2.2 Angstrom Resolution Crystal Structure of putative UDP-N-acetylglucosamine 2-epimerase from Listeria monocytogenes. TO BE PUBLISHED
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3OUT
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![BU of 3out by Molmil](/molmil-images/mine/3out) | Crystal structure of glutamate racemase from Francisella tularensis subsp. tularensis SCHU S4 in complex with D-glutamate. | 分子名称: | D-GLUTAMIC ACID, Glutamate racemase | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Kudriska, M, Edwards, A, Savchenko, A, Anderson, F.W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-15 | 公開日 | 2010-09-29 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of glutamate racemase from Francisella tularensis subsp. tularensis SCHU S4 in complex with D-glutamate. To be Published
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3P52
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![BU of 3p52 by Molmil](/molmil-images/mine/3p52) | NH3-dependent NAD synthetase from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with the nitrate ion | 分子名称: | NH(3)-dependent NAD(+) synthetase, NITRATE ION | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Skarina, T, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-10-07 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | NH3-dependent NAD synthetase from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with the nitrate ion To be Published
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3PAJ
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![BU of 3paj by Molmil](/molmil-images/mine/3paj) | 2.00 Angstrom resolution crystal structure of a quinolinate phosphoribosyltransferase from Vibrio cholerae O1 biovar eltor str. N16961 | 分子名称: | MAGNESIUM ION, Nicotinate-nucleotide pyrophosphorylase, carboxylating | 著者 | Halavaty, A.S, Minasov, G, Winsor, J, Dubrovska, I, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-10-19 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2.00 Angstrom resolution crystal structure of a quinolinate phosphoribosyltransferase from Vibrio cholerae O1 biovar eltor str. N16961 To be Published
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5N68
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![BU of 5n68 by Molmil](/molmil-images/mine/5n68) | Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9m | 分子名称: | 2-(4-morpholin-4-ylphenyl)-~{N}4-(2-phenylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 | 著者 | Buehrmann, M, Mueller, M.P, Rauh, D. | 登録日 | 2017-02-14 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
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5N63
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![BU of 5n63 by Molmil](/molmil-images/mine/5n63) | Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9c | 分子名称: | Mitogen-activated protein kinase 14, ~{N}4-[(4-fluorophenyl)methyl]-2-phenyl-quinazoline-4,7-diamine | 著者 | Buehrmann, M, Mueller, M.P, Rauh, D. | 登録日 | 2017-02-14 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
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3OTR
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![BU of 3otr by Molmil](/molmil-images/mine/3otr) | 2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii | 分子名称: | CHLORIDE ION, Enolase, SULFATE ION | 著者 | Minasov, G, Ruan, J, Shuvalova, L, Halavaty, A, Ngo, H, Tomavo, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-13 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions. Acta Crystallogr.,Sect.D, 71, 2015
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3OO2
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![BU of 3oo2 by Molmil](/molmil-images/mine/3oo2) | 2.37 Angstrom resolution crystal structure of an alanine racemase (alr) from Staphylococcus aureus subsp. aureus COL | 分子名称: | Alanine racemase 1, BETA-MERCAPTOETHANOL, PHOSPHATE ION, ... | 著者 | Halavaty, A.S, Shuvalova, L, Minasov, G, Winsor, J, Dubrovska, I, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-30 | 公開日 | 2010-10-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | 2.37 Angstrom resolution crystal structure of an alanine racemase (alr) from Staphylococcus aureus subsp. aureus COL TO BE PUBLISHED
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3OPQ
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![BU of 3opq by Molmil](/molmil-images/mine/3opq) | Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure. | 分子名称: | CHLORIDE ION, FORMIC ACID, FRUCTOSE -6-PHOSPHATE, ... | 著者 | Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-01 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure. To be Published
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3MJD
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![BU of 3mjd by Molmil](/molmil-images/mine/3mjd) | 1.9 Angstrom Crystal Structure of Orotate Phosphoribosyltransferase (pyrE) Francisella tularensis. | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Orotate phosphoribosyltransferase | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-04-12 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 1.9 Angstrom Crystal Structure of Orotate Phosphoribosyltransferase (pyrE) Francisella tularensis. TO BE PUBLISHED
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5N67
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![BU of 5n67 by Molmil](/molmil-images/mine/5n67) | |
3MAH
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![BU of 3mah by Molmil](/molmil-images/mine/3mah) | A putative c-terminal regulatory domain of aspartate kinase from porphyromonas gingivalis w83. | 分子名称: | Aspartokinase, SULFATE ION | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Moy, S, Joachimiak, A, Anderson, F.W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-03-23 | 公開日 | 2010-04-14 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A Putative C-Terminal Regulatory Domain of Aspartate Kinase from Porphyromonas Gingivalis W83. To be Published
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3MVN
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![BU of 3mvn by Molmil](/molmil-images/mine/3mvn) | Crystal structure of a domain from a putative UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-medo-diaminopimelate ligase from Haemophilus ducreyi 35000HP | 分子名称: | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-medo-diaminopimelate ligase | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, F.W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-05-04 | 公開日 | 2010-06-16 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a domain from a putative UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-medo-diaminopimelate ligase from Haemophilus ducreyi 35000HP To be Published
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