1UVZ
 
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1UZR
 | | Crystal Structure of the Class Ib Ribonucleotide Reductase R2F-2 subunit from Mycobacterium tuberculosis | | 分子名称: | CITRIC ACID, FE (III) ION, GLYCEROL, ... | | 著者 | Uppsten, M, Davis, J, Rubin, H, Uhlin, U. | | 登録日 | 2004-03-15 | | 公開日 | 2004-07-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of the Biologically Active Form of Class Ib Ribonucleotide Reductase Small Subunit from Mycobacterium Tuberculosis
FEBS Lett., 569, 2004
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2DK8
 | | Solution structure of rpc34 subunit in RNA polymerase III from mouse | | 分子名称: | DNA-directed RNA polymerase III 39 kDa polypeptide | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-06 | | 公開日 | 2006-10-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of rpc34 subunit in RNA polymerase III from mouse
To be Published
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1UY9
 | | Human Hsp90-alpha with 8-Benzo[1,3]dioxol-,5-ylmethyl-9-butyl-9H-purin-6-ylamine | | 分子名称: | 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-, HEAT SHOCK PROTEIN HSP 90-ALPHA | | 著者 | Wright, L, Barril, X, Dymock, B, Sheridan, L, Surgenor, A, Beswick, M, Drysdale, M, Collier, A, Massey, A, Davies, N, Fink, A, Fromont, C, Aherne, W, Boxall, K, Sharp, S, Workman, P, Hubbard, R.E. | | 登録日 | 2004-03-02 | | 公開日 | 2004-07-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
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1UYG
 | | Human Hsp90-alpha with 8-(2,5-dimethoxy-benzyl)-2-fluoro-9H-purin-6-ylamine | | 分子名称: | 8-(2,5-DIMETHOXY-BENZYL)-2-FLUORO-9H-PURIN-6-YLAMINE, HEAT SHOCK PROTEIN HSP 90-ALPHA | | 著者 | Wright, L, Barril, X, Dymock, B, Sheridan, L, Surgenor, A, Beswick, M, Drysdale, M, Collier, A, Massey, A, Davies, N, Fink, A, Fromont, C, Aherne, W, Boxall, K, Sharp, S, Workman, P, Hubbard, R.E. | | 登録日 | 2004-03-02 | | 公開日 | 2004-07-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
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1QJ5
 | | Crystal structure of 7,8-diaminopelargonic acid synthase | | 分子名称: | 7,8-DIAMINOPELARGONIC ACID SYNTHASE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Kack, H, Sandmark, J, Gibson, K.J, Lindqvist, Y, Schneider, G. | | 登録日 | 1999-06-21 | | 公開日 | 2000-06-22 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Diaminopelargonic Acid Synthase; Evolutionary Relationships between Pyridoxal-5'-Phosphate Dependent Enzymes
J.Mol.Biol., 291, 1999
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2DVJ
 | | phosphorylated Crk-II | | 分子名称: | V-crk sarcoma virus CT10 oncogene homolog, isoform a | | 著者 | Kobashigawa, Y, Inagaki, F. | | 登録日 | 2006-07-31 | | 公開日 | 2007-05-08 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
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1UVP
 | | Structure Of The Complex Of Porcine Pancreatic Elastase In Complex With Cadmium Refined At 1.85 A Resolution (Crystal B) | | 分子名称: | ACETATE ION, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Weiss, M.S, Panjikar, S, Mueller-Dieckmann, C, Tucker, P.A. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | On the Influence of the Incident Photon Energy on the Radiation Damage in Crystalline Biological Samples
J.Synchrotron Radiat., 12, 2005
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2DE0
 | | Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 | | 分子名称: | Alpha-(1,6)-fucosyltransferase | | 著者 | Taniguchi, N, Ihara, H, Nakagawa, A. | | 登録日 | 2006-02-07 | | 公開日 | 2006-12-26 | | 最終更新日 | 2020-03-25 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structure of mammalian {alpha}1,6-fucosyltransferase, FUT8
Glycobiology, 17, 2007
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1UZ4
 | | Common inhibition of beta-glucosidase and beta-mannosidase by isofagomine lactam reflects different conformational intineraries for glucoside and mannoside hydrolysis | | 分子名称: | (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, GLYCEROL, MAN5A, ... | | 著者 | Vincent, F, Davies, G.J. | | 登録日 | 2004-03-04 | | 公開日 | 2004-11-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Common Inhibition of Both Beta-Glucosidases and Beta-Mannosidases by Isofagomine Lactam Reflects Different Conformational Itineraries for Pyranoside Hydrolysis
Chembiochem, 5, 2004
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1OXQ
 | | Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP) | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, AVPIAQKSE (Smac) peptide, Baculoviral IAP repeat-containing protein 7, ... | | 著者 | Franklin, M.C, Kadkhodayan, S, Ackerly, H, Alexandru, D, Distefano, M.D, Elliott, L.O, Flygare, J.A, Vucic, D, Deshayes, K, Fairbrother, W.J. | | 登録日 | 2003-04-03 | | 公開日 | 2003-08-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)
Biochemistry, 42, 2003
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1OVM
 | | Crystal structure of Indolepyruvate decarboxylase from Enterobacter cloacae | | 分子名称: | Indole-3-pyruvate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | | 著者 | Schutz, A, Sandalova, T, Ricagno, S, Hubner, G, Konig, S, Schneider, G. | | 登録日 | 2003-03-27 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid
Eur.J.Biochem., 270, 2003
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2ESW
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1USD
 | | human VASP tetramerisation domain L352M | | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | | 著者 | Kuhnel, K, Jarchau, T, Wolf, E, Schlichting, I, Walter, U, Wittinghofer, A, Strelkov, S.V. | | 登録日 | 2003-11-21 | | 公開日 | 2004-11-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Vasp Tetramerization Domain is a Right-Handed Coiled Coil Based on a 15-Residue Repeat
Proc.Natl.Acad.Sci.USA, 101, 2004
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1P6L
 | | Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | 著者 | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | | 登録日 | 2003-04-29 | | 公開日 | 2004-01-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
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1P8A
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1VEA
 | | Crystal Structure of HutP, an RNA binding antitermination protein | | 分子名称: | Hut operon positive regulatory protein, N-(2-NAPHTHYL)HISTIDINAMIDE | | 著者 | Kumarevel, T.S, Fujimoto, Z, Karthe, P, Oda, M, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-03-29 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Activated HutP; An RNA Binding Protein that Regulates Transcription of the hut Operon in Bacillus subtilis
Structure, 12, 2004
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2FEQ
 | | orally active thrombin inhibitors | | 分子名称: | Decapeptide Hirudin Analogue, N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({4-[(E)-AMINO(IMINO)METHYL]-1,3-THIAZOL-2-YL}METHYL)-L-PROLINAMIDE, Thrombin heavy chain, ... | | 著者 | Mack, H, Baucke, D, Hornberger, W, Lange, U.E.W, Hoeffken, H.W. | | 登録日 | 2005-12-16 | | 公開日 | 2006-08-08 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Orally active thrombin inhibitors. Part 1: optimization of the P1-moiety
Bioorg.Med.Chem.Lett., 16, 2006
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1OYH
 | | Crystal Structure of P13 Alanine Variant of Antithrombin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... | | 著者 | Johnson, D.J.D, Huntington, J.A. | | 登録日 | 2003-04-04 | | 公開日 | 2004-04-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | The influence of hinge region residue Glu-381 on antithrombin allostery and metastability
J.Biol.Chem., 279, 2004
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1TIH
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2F0Y
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1QH3
 | | HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE | | 分子名称: | ACETATE ION, CACODYLATE ION, CHLORIDE ION, ... | | 著者 | Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B. | | 登録日 | 1999-05-10 | | 公開日 | 1999-09-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
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2D5Z
 | | Crystal structure of T-state human hemoglobin complexed with three L35 molecules | | 分子名称: | 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID, Hemoglobin alpha subunit, Hemoglobin beta subunit, ... | | 著者 | Yokoyama, T, Neya, S, Tsuneshige, A, Yonetani, T, Park, S.Y, Tame, J.R. | | 登録日 | 2005-11-08 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35
J.Mol.Biol., 356, 2006
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2D34
 | | FORMALDEHYDE CROSS-LINKS DAUNORUBICIN AND DNA EFFICIENTLY: HPLC AND X-RAY DIFFRACTION STUDIES | | 分子名称: | 5'-D(*CP*GP*TP*(A35)P*CP*G)-3', DAUNOMYCIN, MAGNESIUM ION | | 著者 | Wang, A.H.-J, Gao, Y.-G, Liaw, Y.-C, Li, Y.-K. | | 登録日 | 1991-05-23 | | 公開日 | 1992-04-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
Biochemistry, 30, 1991
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1QTU
 | | SOLUTION STRUCTURE OF THE ONCOPROTEIN P13MTCP1 | | 分子名称: | PROTEIN (PRODUCT OF THE MTCP1 ONCOGENE) | | 著者 | Guignard, L, Padilla, A, Mispelter, J, Yang, Y.-S, Stern, M.-H, Lhoste, J.-M, Roumestand, C. | | 登録日 | 1999-06-29 | | 公開日 | 2001-01-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data.
J.Biomol.NMR, 17, 2000
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