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1IGY
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STRUCTURE OF IMMUNOGLOBULIN
分子名称: IGG1 INTACT ANTIBODY MAB61.1.3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Harris, L.J, McPherson, A.
登録日1997-10-09
公開日1998-04-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic structure of an intact IgG1 monoclonal antibody.
J.Mol.Biol., 275, 1998
3UBX
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Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex
分子名称: (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yu, E.D, Zajonc, D.M.
登録日2011-10-25
公開日2011-11-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.
J.Biol.Chem., 287, 2012
3UYR
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Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-06
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UO1
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Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-11-16
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
4FQQ
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Crystal Structure of Germline Antibody PGT121-GL Fab
分子名称: Fab heavy chain, Fab light chain, SODIUM ION
著者Scharf, L, Bjorkman, P.J.
登録日2012-06-25
公開日2012-11-14
最終更新日2021-05-19
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4O5L
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Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4OQT
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LINGO-1/Li81 Fab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ...
著者Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S.
登録日2014-02-10
公開日2014-05-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy.
J.Pharmacol.Exp.Ther., 350, 2014
2GAZ
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Mycobacterial lipoglycan presentation by CD1d
分子名称: (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ...
著者Zajonc, D.M.
登録日2006-03-09
公開日2006-09-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d.
J.Immunol., 177, 2006
2G2R
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Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
分子名称: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
著者Debler, E.W, Wilson, I.A.
登録日2006-02-16
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
2G60
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Structure of anti-FLAG M2 Fab domain
分子名称: anti-FLAG M2 Fab heavy chain, anti-FLAG M2 Fab light chain
著者Roosild, T.P.
登録日2006-02-23
公開日2006-09-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.
Acta Crystallogr.,Sect.F, 62, 2006
2G5B
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Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ...
著者Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W.
登録日2006-02-22
公開日2006-07-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
7XT6
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Structure of a membrane protein M3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain, ...
著者Ma, X, Zhu, Y, Chen, Y, Huang, Z.
登録日2022-05-16
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Cryo-EM structures of two human B cell receptor isotypes.
Science, 377, 2022
7XXL
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RBD in complex with Fab14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab14 heavy chain, Fab14 light chain, ...
著者Lin, J.Q, Tan, Y.J.E, Wu, B, Lescar, J.
登録日2022-05-30
公開日2022-09-14
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Nat Commun, 13, 2022
1MCH
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PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1M7I
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE
分子名称: alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-methyl 6-deoxy-alpha-L-rhamnopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-19
公開日2003-07-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1MCB
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PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
分子名称: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH
著者Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W.
登録日1993-02-25
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Principles and pitfalls in designing site-directed peptide ligands.
Proteins, 16, 1993
1MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE
著者Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
登録日1997-02-26
公開日1997-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
6KXS
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Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Li, Y, Wang, G, Xiao, J.
登録日2019-09-12
公開日2020-02-05
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into immunoglobulin M.
Science, 367, 2020
8SGM
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.50000215 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
8SGB
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.80001545 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
4UDT
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T cell receptor (TRAV22,TRBV7-9) structure
分子名称: GLYCEROL, PROTEIN TRBV7-9, T-CELL RECEPTOR BETA-2 CHAIN C REGION, ...
著者Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K.
登録日2014-12-11
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of Staphylococcal Enterotoxin E in Complex with Tcr Defines the Role of Tcr Loop Positioning in Superantigen Recognition.
Plos One, 10, 2015
7B0B
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Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ...
著者Borenstein-Katz, A, Diskin, R.
登録日2020-11-19
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.
Immunity, 56, 2023
3GML
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Structure of mouse CD1d in complex with C6Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMP
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Structure of mouse CD1d in complex with PBS-25
分子名称: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMN
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Structure of mouse CD1d in complex with C10Ph
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
著者Schiefner, A, Wilson, I.A.
登録日2009-03-14
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009

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