PDB: 909 件ウェブページステータス検索Chemie searchBIRD

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2N7C	Solution structure of Plasmodium falciparum SR1-RRM1 in complex with ACAUCA RNA 分子名称: RNA_(5'-R(*AP*CP*AP*UP*CP*A)-3'), putative splicing factor 著者 Ganguly, A.K, Verma, G, Bhavesh, N.S. 登録日 2015-09-08 公開日 2016-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The N-terminal RNA Recognition Motif of PfSR1 Confers Semi-specificity for Pyrimidines during RNA Recognition. J. Mol. Biol., 431, 2019
2O3D	Structure of human SF2/ASF RNA recognition motif 2 (RRM2) 分子名称: Splicing factor, arginine/serine-rich 1 著者 Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A. 登録日 2006-12-01 公開日 2007-10-16 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structural and functional analysis of RNA and TAP binding to SF2/ASF. Embo Rep., 8, 2007
2PE8	Crystal structure of the UHM domain of human SPF45 (free form) 分子名称: Splicing factor 45 著者 Corsini, L, Basquin, J, Hothorn, M, Sattler, M. 登録日 2007-04-02 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
2OSQ	NMR Structure of RRM-1 of Yeast NPL3 Protein 分子名称: Nucleolar protein 3 著者 Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. 登録日 2007-02-06 公開日 2007-12-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J.Mol.Biol., 375, 2008
2OIH	Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ 分子名称: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A 著者 Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. 登録日 2007-01-11 公開日 2007-03-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
2OJ3	Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) 分子名称: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... 著者 Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. 登録日 2007-01-12 公開日 2007-03-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
2NZ4	Structural investigation of the GlmS ribozyme bound to its catalytic cofactor 分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GlmS ribozyme, MAGNESIUM ION, ... 著者 Cochrane, J.C. 登録日 2006-11-22 公開日 2007-01-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Structural Investigation of the GlmS Ribozyme Bound to Its Catalytic Cofactor Chem.Biol., 14, 2007
2PEH	Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 分子名称: Splicing factor 3B subunit 1, Splicing factor 45 著者 Corsini, L, Basquin, J, Hothorn, M, Sattler, M. 登録日 2007-04-03 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
2QFJ	Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE 分子名称: DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor 著者 Crichlow, G.V, Yang, Y, Fan, C, Lolis, E, Braddock, D. 登録日 2007-06-27 公開日 2008-03-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition EMBO J., 27, 2007
2OSR	NMR Structure of RRM-2 of Yeast NPL3 Protein 分子名称: Nucleolar protein 3 著者 Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. 登録日 2007-02-06 公開日 2007-12-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J.Mol.Biol., 375, 2008
2MY3	Snu17p-Pml1p structure intermediate during RES complex assembly 分子名称: Pre-mRNA leakage protein 1, U2 snRNP component IST3 著者 Wysoczanski, P, Becker, S, Zweckstetter, M. 登録日 2015-01-19 公開日 2015-08-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structures of intermediates during RES complex assembly. Sci Rep, 5, 2015
2N82	solution structure of the complex of microRNA 20b pre-element with Rbfox RRM 分子名称: RNA (5'-R(*GP*GP*UP*AP*GP*UP*UP*UP*UP*GP*GP*CP*AP*UP*GP*AP*CP*UP*CP*UP*AP*CP*C)-3'), RNA binding protein fox-1 homolog 1 著者 Yang, F, Chen, Y, Varani, G. 登録日 2015-09-30 公開日 2016-04-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer. Nucleic Acids Res., 44, 2016
9F4E	UP1 in complex with Z1152242726 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(6-methoxypyridin-3-yl)-N'-thiophen-2-ylurea 著者 Dunnett, L, Prischi, F. 登録日 2024-04-27 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4D	UP1 in complex with Z1203107138 分子名称: 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-27 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4F	UP1 in complex with Z86417414 分子名称: 2-fluoranyl-~{N}-(1,3,4-thiadiazol-2-yl)benzamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-27 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4T	UP1 in complex with EN300-805013 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(4-methoxyphenyl)glycinamide 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4K	UP1 in complex with ZINC72259689 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(cyclobutylmethyl)-1,3-dimethyl-pyrazole-4-carboxamide 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4R	UP1 in complex with Z802821712 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-ethyl-6-methylpyridazin-3-amine 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4X	UP1 in complex with Z1220452176 分子名称: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Q	UP1 in complex with Z641239276 分子名称: 5-(2-phenylethylamino)pyrimidine-2,4-diol, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F54	UP1 in complex with EN300-197154 分子名称: 1-methyl-3-[(3R)-piperidin-3-yl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Y	UP1 in complex with Z90120418 分子名称: 1-(3,4,5-trimethoxyphenyl)methanamine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4G	UP1 in complex with Z1373445602 分子名称: 4-(3-fluoranylpyridin-2-yl)-1-methyl-piperazin-2-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-27 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4J	UP1 in complex with Z416341642 分子名称: (2R)-N,2-dimethyl-N-(propan-2-yl)morpholine-4-sulfonamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4P	UP1 in complex with Z1217960891 分子名称: (3S)-3-(3-fluorophenoxy)-1-methylpyrrolidin-2-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published

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