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4C0Q
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BU of 4c0q by Molmil
Transportin 3 in complex with Ran(Q69L)GTP
分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Maertens, G, Hare, S, Cherepanov, P.
登録日2013-08-06
公開日2014-01-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural Basis for Nuclear Import of Splicing Factors by Human Transportin 3.
Proc.Natl.Acad.Sci.USA, 111, 2014
4C4P
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BU of 4c4p by Molmil
Crystal Structure of Wild-Type Rab11 Complexed to FIP2
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB11 FAMILY-INTERACTING PROTEIN 2, ...
著者Sultana, A, Khan, A.R.
登録日2013-09-07
公開日2013-09-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Analysis of Fip2 Binding to the Endosome-Localised Rab25 Gtpase
Biochim.Biophys.Acta, 1834, 2013
4CYM
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BU of 4cym by Molmil
Complex of human VARP-ANKRD1 with Rab32-GppCp
分子名称: ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R.
登録日2014-04-13
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
4CZ2
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BU of 4cz2 by Molmil
Complex of human VARP-ANKRD1 with Rab32-GppCp. Selenomet derivative.
分子名称: ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R.
登録日2014-04-16
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
4D0G
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BU of 4d0g by Molmil
Structure of Rab14 in complex with Rab-Coupling Protein (RCP)
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RAB11 FAMILY-INTERACTING PROTEIN 1, ...
著者Lall, P, Khan, A.R.
登録日2014-04-25
公開日2015-05-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Function Analyses of the Interactions between Rab11 and Rab14 Small Gtpases with Their Shared Effector Rab Coupling Protein (Rcp).
J.Biol.Chem., 290, 2015
4D0L
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BU of 4d0l by Molmil
Phosphatidylinositol 4-kinase III beta-PIK93 in a complex with Rab11a- GTP gammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, ...
著者Burke, J.E, Inglis, A.J, Perisic, O, Masson, G.R, McLaughin, S.H, Rutaganira, F, Shokat, K.M, Williams, R.L.
登録日2014-04-29
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.
Science, 344, 2014
4D0M
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Phosphatidylinositol 4-kinase III beta in a complex with Rab11a-GTP- gamma-S and the Rab-binding domain of FIP3
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, ...
著者Burke, J.E, Inglis, A.J, Perisic, O, Masson, G.R, McLaughlin, S.H, Rutaganira, F, Shokat, K.M, Williams, R.L.
登録日2014-04-29
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.
Science, 344, 2014
4D0N
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BU of 4d0n by Molmil
AKAP13 (AKAP-Lbc) RhoGEF domain in complex with RhoA
分子名称: 1,2-ETHANEDIOL, A-KINASE ANCHOR PROTEIN 13, GUANOSINE-5'-DIPHOSPHATE, ...
著者Abdul Azeez, K.R, Shrestha, L, Krojer, T, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A.M, Knapp, S, Klussmann, E, Elkins, J.M.
登録日2014-04-29
公開日2014-05-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex.
Biochem.J., 464, 2014
4DID
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BU of 4did by Molmil
Crystal structure of Salmonella effector N-terminal domain SopB in complex with Cdc42
分子名称: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Inositol phosphate phosphatase sopB, ...
著者Burkinshaw, B.J, Strynadka, N.C.J.
登録日2012-01-30
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3501 Å)
主引用文献Structure of Salmonella Effector Protein SopB N-terminal Domain in Complex with Host Rho GTPase Cdc42.
J.Biol.Chem., 287, 2012
4DKX
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BU of 4dkx by Molmil
Crystal Structure of the Rab 6A'(Q72L)
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-6A
著者Park, H.H, Shin, Y.-C.
登録日2012-02-04
公開日2012-10-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/Mg2+ binding with opened GTP-binding domain
Biochem.Biophys.Res.Commun., 424, 2012
4DLR
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BU of 4dlr by Molmil
H-Ras PEG 400/Ca(OAc)2, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.319 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLS
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BU of 4dls by Molmil
H-Ras Set 1 CaCl2 'Mixed'
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLT
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BU of 4dlt by Molmil
H-Ras Set 2 Ca(OAc)2, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLU
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BU of 4dlu by Molmil
H-Ras Set 1 Ca(OAc)2, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLV
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BU of 4dlv by Molmil
H-Ras Set 2 CaCl2/DTT, ordered off
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.572 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLW
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BU of 4dlw by Molmil
H-Ras Set 2 Ca(OAc)2/DTT, on
分子名称: ACETATE ION, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLX
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BU of 4dlx by Molmil
H-Ras Set 1 CaCl2/DTE, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.731 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLY
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BU of 4dly by Molmil
Set 1 CaCl2/DTT, ordered off
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DLZ
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BU of 4dlz by Molmil
H-Ras Set 2 Ca(OAc)2/DTE, ordered off
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
著者Holzapfel, G, Mattos, C.
登録日2012-02-06
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.662 Å)
主引用文献Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
4DRZ
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BU of 4drz by Molmil
Crystal structure of human RAB14
分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-14
著者Wang, J, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2012-02-17
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human RAB14
to be published
4DSN
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BU of 4dsn by Molmil
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 1,2-ETHANEDIOL, GTPase KRas, isoform 2B, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSO
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BU of 4dso by Molmil
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DST
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BU of 4dst by Molmil
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: 1,2-ETHANEDIOL, 2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine, ACETATE ION, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DSU
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BU of 4dsu by Molmil
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
分子名称: BENZIMIDAZOLE, GTPase KRas, isoform 2B, ...
著者Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W.
登録日2012-02-19
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DVG
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BU of 4dvg by Molmil
Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Diaphanous protein, MAGNESIUM ION, ...
著者Bosch, D.E, Siderovski, D.P.
登録日2012-02-23
公開日2012-11-14
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin.
Biochemistry, 51, 2012

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